spironolactone has been researched along with Peptic Ulcer in 10 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, A | 1 |
| Autelitano, M | 1 |
| Bisanti, L | 1 |
| Trewby, PN | 1 |
| Tomkins, AM | 1 |
| Edmonds, CJ | 1 |
| Hoffmeister, W | 1 |
| Hoffmeister, AW | 1 |
| Selye, H | 2 |
| Mécs, I | 1 |
| Kremer, D | 1 |
| Fraser, R | 1 |
| Brown, JJ | 1 |
| Lever, AF | 1 |
| Davies, DL | 1 |
| Robertson, JI | 1 |
| Gerstein, AR | 1 |
| Franklin, SS | 1 |
| Kleeman, CR | 1 |
| Maxwell, MH | 1 |
| Gold, EM | 1 |
| Kjeldsen, K | 1 |
| Sand, H | 1 |
1 review available for spironolactone and Peptic Ulcer
| Article | Year |
|---|---|
Drug-induced peptic ulcer and upper gastrointestinal bleeding.
Topics: Adrenal Cortex Hormones; Alcoholism; Animals; Aspirin; Diuretics; Emepronium; Female; Gastrointestin | 1980 |
9 other studies available for spironolactone and Peptic Ulcer
| Article | Year |
|---|---|
Spironolactone and gastrointestinal bleeding: a population based study.
Topics: Aged; Aged, 80 and over; Bias; Cohort Studies; Diuretics; Dose-Response Relationship, Drug; Female; | 2008 |
Electrical potential difference, sodium absorption and potassium secretion by the human rectum during carbenoxolone therapy.
Topics: Adult; Aged; Amiloride; Bendroflumethiazide; Carbenoxolone; Dialysis; Electrophysiology; Humans; Hyd | 1975 |
[Experimental study on the prevention of steroid-induced gastric ulcer].
Topics: Aldosterone; Animals; Antacids; Cellulose; Desoxycorticosterone; Female; Gastric Juice; Gastrointest | 1971 |
Blockade of catatoxic steroid actions by metyrapone.
Topics: Adrenocorticotropic Hormone; Animals; Digitoxin; Female; Indomethacin; Metyrapone; Peptic Ulcer; Rat | 1970 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Fe | 1973 |
Editorial: Drugs for gastric ulceration.
Topics: Bismuth; Cholestyramine Resin; Diethylstilbestrol; Diuresis; Dose-Response Relationship, Drug; Glycy | 1974 |
Prevention of indomethacin-induced intestinal ulcers by spironolactone and norbolethone.
Topics: Anabolic Agents; Animals; Digestive System; Female; Indomethacin; Peptic Ulcer; Peritonitis; Rats; S | 1969 |
Potassium losing pyelonephritis. Response to spironolactone.
Topics: Aged; Diet Therapy; Humans; Hyperaldosteronism; Hypokalemia; Male; Peptic Ulcer; Potassium; Potassiu | 1969 |
[Mineral-corticoid activity of licorice].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Glycyrrhiza; Humans; Male; Middle Aged; Myocardial Infar | 1965 |