spironolactone has been researched along with Osteoarthritis of Knee in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mcmurdo, ME | 1 |
| Sumukadas, D | 1 |
| Donnan, PT | 1 |
| Cvoro, V | 1 |
| Rauchhaus, P | 1 |
| Argo, I | 1 |
| Waldie, H | 1 |
| Littleford, R | 1 |
| Struthers, AD | 1 |
| Witham, MD | 1 |
| Elsaman, AM | 1 |
| Radwan, AR | 1 |
| Mohammed, WI | 1 |
| Ohrndorf, S | 1 |
1 trial available for spironolactone and Osteoarthritis of Knee
| Article | Year |
|---|---|
Spironolactone for People Age 70 Years and Older With Osteoarthritic Knee Pain: A Proof-of-Concept Trial.
Topics: Aged; Aged, 80 and over; Arthralgia; Double-Blind Method; Female; Humans; Intention to Treat Analysi | 2016 |
1 other study available for spironolactone and Osteoarthritis of Knee
| Article | Year |
|---|---|
Low-dose Spironolactone: Treatment for Osteoarthritis-related Knee Effusion. A Prospective Clinical and Sonographic-based Study.
Topics: Adult; Anti-Inflammatory Agents; Cryotherapy; Exudates and Transudates; Female; Humans; Ibuprofen; K | 2016 |