spironolactone has been researched along with Orphan Diseases in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Orphan Diseases: Rare diseases that have not been well studied.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sedhom, R | 1 |
| Hu, S | 1 |
| Ohri, A | 1 |
| Infantino, D | 1 |
| Lubitz, S | 1 |
| Park, PG | 1 |
| Karet Frankl, FE | 1 |
2 other studies available for spironolactone and Orphan Diseases
| Article | Year |
|---|---|
Symptomatic Cushing's syndrome and hyperandrogenemia in a steroid cell ovarian neoplasm: a case report.
Topics: Aged; Antineoplastic Agents, Hormonal; Cushing Syndrome; Disease Progression; Fatal Outcome; Female; | 2016 |
Gitelman syndrome.
Topics: Disease Management; General Practitioners; Gitelman Syndrome; Humans; Hypokalemia; Interprofessional | 2012 |