spironolactone has been researched along with Oliguria in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Oliguria: Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To test the hypothesis that aldosterone can cause hypertension in a manner that does not involve renal sodium retention, we administered eplerenone, a specific aldosterone antagonist, to oligo-anuric chronic hemodialysis patients who had HTN." | 3.77 | Effect of eplerenone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric chronic hemodialysis patients - a pilot study. ( Lifschitz, M; Neykin, D; Shavit, L; Slotki, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shavit, L | 1 |
| Neykin, D | 1 |
| Lifschitz, M | 1 |
| Slotki, I | 1 |
| Gross, E | 1 |
| Rothstein, M | 1 |
| Dombek, S | 1 |
| Juknis, HI | 1 |
| Schohn, DC | 1 |
| Jahn, HA | 1 |
| Pelletier, BC | 1 |
1 trial available for spironolactone and Oliguria
| Article | Year |
|---|---|
Effect of spironolactone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric hemodialysis patients.
Topics: Adult; Aldosterone; Antihypertensive Agents; Anuria; Blood Pressure; Body Weight; Cross-Over Studies | 2005 |
2 other studies available for spironolactone and Oliguria
| Article | Year |
|---|---|
Effect of eplerenone on blood pressure and the renin-angiotensin-aldosterone system in oligo-anuric chronic hemodialysis patients - a pilot study.
Topics: Aged; Anuria; Blood Pressure; Eplerenone; Female; Humans; Hypertension; Male; Middle Aged; Mineraloc | 2011 |
Dose-related cardiovascular effects of spironolactone.
Topics: Adult; Dose-Response Relationship, Drug; Hemodynamics; Humans; Male; Middle Aged; Oliguria; Renal Di | 1993 |