spironolactone has been researched along with Oligomenorrhea in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Oligomenorrhea: Abnormally infrequent menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate and compare the effects of spironolactone and spironolactone plus metformin treatments on body mass index (BMI), hirsutism score, hormone levels, and insulin resistance in women with polycystic ovary syndrome (PCOS)." | 9.22 | Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome. ( Acmaz, B; Diri, H; Karaburgu, S; Karaca, Z; Kelestimur, F; Tanriverdi, F; Unluhizarci, K, 2016) |
| "The aim of this study was to evaluate and compare the effects of spironolactone and spironolactone plus metformin treatments on body mass index (BMI), hirsutism score, hormone levels, and insulin resistance in women with polycystic ovary syndrome (PCOS)." | 5.22 | Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome. ( Acmaz, B; Diri, H; Karaburgu, S; Karaca, Z; Kelestimur, F; Tanriverdi, F; Unluhizarci, K, 2016) |
| "Low-dose spironolactone improves hirsutism in a majority of hirsute women, irrespective of age, severity or duration of hirsutism, menstrual status, or serum hormone levels." | 3.68 | Predictors of clinical response in hirsute women treated with spironolactone. ( Crosby, PD; Rittmaster, RS, 1991) |
| "Thirteen anovulatory oligomenorrheic, hyperandrogenic, and normoprolactinemic women were treated with spironolactone (aldactone) throughout six consecutive menstrual cycles in a dosage of 100 to 150 mg/day." | 1.26 | Induction of ovulation with spironolactone (Aldactone) in anovulatory oligomenorrheic and hyperandrogenic women. ( Diamant, YZ; Evron, S; Shapiro, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ibáñez, L | 1 |
| Del Río, L | 1 |
| Díaz, M | 1 |
| Sebastiani, G | 1 |
| Pozo, ÓJ | 1 |
| López-Bermejo, A | 1 |
| de Zegher, F | 1 |
| Diri, H | 1 |
| Karaburgu, S | 1 |
| Acmaz, B | 1 |
| Unluhizarci, K | 1 |
| Tanriverdi, F | 1 |
| Karaca, Z | 1 |
| Kelestimur, F | 1 |
| Evron, S | 1 |
| Shapiro, G | 1 |
| Diamant, YZ | 1 |
| Crosby, PD | 1 |
| Rittmaster, RS | 1 |
| Siegberg, R | 1 |
| Ylöstalo, P | 1 |
| Laatikainen, T | 1 |
| Pelkonen, R | 1 |
| Stenman, UH | 1 |
3 trials available for spironolactone and Oligomenorrhea
| Article | Year |
|---|---|
Normalizing Ovulation Rate by Preferential Reduction of Hepato-Visceral Fat in Adolescent Girls With Polycystic Ovary Syndrome.
Topics: Adolescent; Body Mass Index; Contraceptives, Oral, Combined; Drug Combinations; Ethinyl Estradiol; F | 2017 |
Comparison of spironolactone and spironolactone plus metformin in the treatment of polycystic ovary syndrome.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Dehydroepiandrosterone Sulfate; Drug Therapy, Com | 2016 |
Endocrine and clinical effects of spironolactone in female hyperandrogenism.
Topics: Adult; Amenorrhea; Androgens; Double-Blind Method; Endocrine System Diseases; Female; Gonadotropins, | 1987 |
2 other studies available for spironolactone and Oligomenorrhea
| Article | Year |
|---|---|
Induction of ovulation with spironolactone (Aldactone) in anovulatory oligomenorrheic and hyperandrogenic women.
Topics: 17-Ketosteroids; Androgens; Anovulation; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Lu | 1981 |
Predictors of clinical response in hirsute women treated with spironolactone.
Topics: Adolescent; Adult; Age Factors; Body Mass Index; Child; Contraceptives, Oral; Dehydroepiandrosterone | 1991 |