spironolactone has been researched along with Neutropenia in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to assess the ability of spironolactone to reduce potassium requirements and to prevent hypokalemia in neutropenic patients on AmB treatment." | 9.10 | Spironolactone: is it a novel drug for the prevention of amphotericin B-related hypokalemia in cancer patients? ( Avcu, F; Beyan, C; Cetin, T; Kaptan, K; Nazaroglu, NK; Ural, AU; Yalcin, A, 2002) |
| " This study was designed to assess the ability of spironolactone to reduce potassium requirements and to prevent hypokalemia in neutropenic patients on AmB treatment." | 5.10 | Spironolactone: is it a novel drug for the prevention of amphotericin B-related hypokalemia in cancer patients? ( Avcu, F; Beyan, C; Cetin, T; Kaptan, K; Nazaroglu, NK; Ural, AU; Yalcin, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ural, AU | 2 |
| Avcu, F | 1 |
| Cetin, T | 1 |
| Beyan, C | 1 |
| Kaptan, K | 1 |
| Nazaroglu, NK | 1 |
| Yalcin, A | 1 |
1 trial available for spironolactone and Neutropenia
| Article | Year |
|---|---|
Spironolactone: is it a novel drug for the prevention of amphotericin B-related hypokalemia in cancer patients?
Topics: Amphotericin B; Antifungal Agents; Humans; Hypokalemia; Kidney Function Tests; Mineralocorticoid Rec | 2002 |
1 other study available for spironolactone and Neutropenia
| Article | Year |
|---|---|
Comment: spironolactone prevents amphotericin B-induced hypokalemia in neutropenic patients.
Topics: Amphotericin B; Drug Interactions; Humans; Hypokalemia; Mineralocorticoid Receptor Antagonists; Neut | 2000 |