spironolactone has been researched along with Nephrosis in 10 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty Caucasian patients with diabetic nephropathy and nephrotic range albuminuria (>2500 mg/24 h) despite recommended antihypertensive treatment completed this double-masked, randomized crossover trial." | 6.72 | Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. ( Boomsma, F; Juhl, TR; Parving, HH; Rossing, K; Rossing, P; Schjoedt, KJ; Tarnow, L, 2006) |
| "Twenty Caucasian patients with diabetic nephropathy and nephrotic range albuminuria (>2500 mg/24 h) despite recommended antihypertensive treatment completed this double-masked, randomized crossover trial." | 2.72 | Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. ( Boomsma, F; Juhl, TR; Parving, HH; Rossing, K; Rossing, P; Schjoedt, KJ; Tarnow, L, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GILSANZ, V | 1 |
| BARRIO, E | 1 |
| CEBRIAN, L | 1 |
| ESTELLA, J | 1 |
| LOCKWOOD, CH | 1 |
| NICHOLLS, DM | 1 |
| LEWIS, JA | 1 |
| TROOP, VL | 1 |
| ANIBALDI, A | 2 |
| BOSCHERINI, B | 2 |
| PAIELLA, R | 1 |
| PATANE, E | 1 |
| PEDULLA, T | 1 |
| POLIANTSEVA, LR | 1 |
| ERMOLENKO, VM | 1 |
| SHETH, UK | 1 |
| VAIDYA, A | 1 |
| KHOKHANI, RC | 1 |
| SHAH, MJ | 1 |
| GOLINELLI, G | 1 |
| MELLI, A | 1 |
| Schjoedt, KJ | 1 |
| Rossing, K | 1 |
| Juhl, TR | 1 |
| Boomsma, F | 1 |
| Tarnow, L | 1 |
| Rossing, P | 1 |
| Parving, HH | 1 |
| Carey, RM | 1 |
| Wooster, LD | 1 |
| Hook, EW | 1 |
| Köhler, JA | 1 |
1 trial available for spironolactone and Nephrosis
| Article | Year |
|---|---|
Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy.
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitor | 2006 |
9 other studies available for spironolactone and Nephrosis
| Article | Year |
|---|---|
[PERITONEAL DIALYSIS (D.P.): ITS EFFICIENCY IN IRREDUCIBLE EDEMAS AFTER FAILURE OF OTHER TREATMENTS].
Topics: Amyloidosis; Bronchiectasis; Dialysis; Edema; Empyema; Heart Failure; Liver Cirrhosis; Nephrosis; Pe | 1963 |
THE DIURETIC EFFECT OF TRIAMTERENE.
Topics: Blood Chemical Analysis; Coronary Disease; Creatine; Creatinine; Diuretics; Heart Failure; Hypertens | 1964 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE ANTAGONISTS IN THE THERAPY OF INFANTILE NEPHROTIC EDEMA. II. STUDY OF OSMOLAR CLEARANCES AND FREE WATER].
Topics: Child; Diuresis; Edema; Glomerulonephritis; Humans; Hydrochlorothiazide; Ketones; Kidney Function Te | 1963 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE IN THE THERAPY OF NEPHROTIC EDEMA. I. CLINICAL RESULTS AND STUDY OF WATER AND SALT METABOLISM IN 3 CASES].
Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Edema; Glomerulonephritis; Humans; Hydrochlorothiaz | 1963 |
[ALDOSTERONE AND SPIROLACTONES IN THE CLINICAL TREATMENT OF INTERNAL DISEASES (REVIEW OF THE LITERATURE AND ANALYSIS OF PERSONAL CASES)].
Topics: Albuminuria; Aldosterone; Blood; Cardiovascular Diseases; Drug Therapy; Humans; Hyperaldosteronism; | 1963 |
CLINICAL ASSESSMENT OF DIURETICS.
Topics: Acetazolamide; Body Weight; Diuretics; Drug Therapy; Edema; Heart Failure; Liver Cirrhosis; Nephrosi | 1964 |
[POTENTIATION OF MERCURIAL DIURETICS WITH PROGESTERONE].
Topics: Chemistry, Pharmaceutical; Diuretics; Edema; Heart Failure; Liver Cirrhosis; Mineralocorticoid Recep | 1964 |
Idiopathic edema.
Topics: Adult; Age Factors; Aldosterone; Edema; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrosta | 1974 |
[The patient with edema].
Topics: Adolescent; Adult; Dietary Proteins; Diuretics; Edema; Electrocardiography; Female; Heart Failure; H | 1969 |