Page last updated: 2024-11-07

spironolactone and Nausea

spironolactone has been researched along with Nausea in 7 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"Eplerenone is a highly selective aldosterone blocker, which is under development for the treatment of hypertension and heart failure."9.10Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension. ( Duprez, D; Krause, S; Kuse-Hamilton, J; Roniker, B; St Hillaire, R; Weber, MA; White, WB, 2003)
"Thirty-five consecutive patients with acne were treated with spironolactone 100 mg/day, 16 days each month for 3 months."7.73Effects and side-effects of spironolactone therapy in women with acne. ( Gorgulu, A; Piskin, S; Yemisci, A, 2005)
"Eplerenone is a highly selective aldosterone blocker, which is under development for the treatment of hypertension and heart failure."5.10Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension. ( Duprez, D; Krause, S; Kuse-Hamilton, J; Roniker, B; St Hillaire, R; Weber, MA; White, WB, 2003)
"Thirty-five consecutive patients with acne were treated with spironolactone 100 mg/day, 16 days each month for 3 months."3.73Effects and side-effects of spironolactone therapy in women with acne. ( Gorgulu, A; Piskin, S; Yemisci, A, 2005)
"In conclusion, hypokalemia is extremely common in patients presenting with VT/VF, much more so than in patients with CHF alone."1.56Electrolyte Abnormalities in Patients Presenting With Ventricular Arrhythmia (from the LYTE-VT Study). ( Basil, A; Cooper, JM; Gangireddy, C; Greenberg, RM; Laslett, DB; Whitman, IR; Yesenosky, GA, 2020)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Laslett, DB1
Cooper, JM1
Greenberg, RM1
Yesenosky, GA1
Basil, A1
Gangireddy, C1
Whitman, IR1
White, WB1
Duprez, D1
St Hillaire, R1
Krause, S1
Roniker, B1
Kuse-Hamilton, J1
Weber, MA1
Yemisci, A1
Gorgulu, A1
Piskin, S1
Wortsman, J1
Soler, NG1
Gayral, MN1
Millet, D1
Netter, A1
Lvoff, R1
Wilcken, DE1
Greenblatt, DJ1
Koch-Weser, J1

Trials

1 trial available for spironolactone and Nausea

ArticleYear
Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:5

    Topics: Aged; Albuminuria; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channe

2003

Other Studies

6 other studies available for spironolactone and Nausea

ArticleYear
Electrolyte Abnormalities in Patients Presenting With Ventricular Arrhythmia (from the LYTE-VT Study).
    The American journal of cardiology, 2020, 08-15, Volume: 129

    Topics: Aged; Cardiomyopathies; Case-Control Studies; Diarrhea; Diuretics; Female; Heart Failure; Humans; Hy

2020
Effects and side-effects of spironolactone therapy in women with acne.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2005, Volume: 19, Issue:2

    Topics: Acne Vulgaris; Adult; Androgen Receptor Antagonists; Case-Control Studies; Dehydroepiandrosterone Su

2005
Mitotane. Spironolactone antagonism in Cushing's syndrome.
    JAMA, 1977, Dec-05, Volume: 238, Issue:23

    Topics: Aged; Cushing Syndrome; Diarrhea; Female; Humans; Hypokalemia; Mitotane; Nausea; Spironolactone

1977
[Ovarian hyperstimulation syndrome. Notes on the physiopathology and treatment apropos of 3 cases].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1975, Volume: 4, Issue:2

    Topics: Adult; Ascites; Capillary Permeability; Chorionic Gonadotropin; Female; Gonadotropins, Pituitary; Hu

1975
Glucagon in heart failure and in cardiogenic shock. Experience in 50 patients.
    Circulation, 1972, Volume: 45, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Body Weight; Digital

1972
Adverse reactions to spironolactone. A report from the Boston Collaborative Drug Surveillance Program.
    JAMA, 1973, Jul-02, Volume: 225, Issue:1

    Topics: Adult; Aged; Blood Urea Nitrogen; Coma; Dehydration; Diarrhea; Female; Gynecomastia; Headache; Heart

1973