spironolactone has been researched along with Muscle Relaxation in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with aldosterone also significantly extended the mean (SEM) time required to reach 50% relaxation of a noradrenaline-induced contraction, of 9." | 1.35 | Effect of aldosterone on isolated human penile corpus cavernosum tissue. ( Anzai, H; Kagawa, J; Kanayama, HO; Kawanishi, Y; Kishimoto, T; Kojima, K; Muguruma, H; Numata, A; Sugiyama, H; Tanimoto, S; Yamanaka, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pojoga, LH | 1 |
| Adamová, Z | 1 |
| Kumar, A | 1 |
| Stennett, AK | 1 |
| Romero, JR | 1 |
| Adler, GK | 1 |
| Williams, GH | 1 |
| Khalil, RA | 1 |
| Muguruma, H | 1 |
| Kawanishi, Y | 1 |
| Sugiyama, H | 1 |
| Kagawa, J | 1 |
| Tanimoto, S | 1 |
| Yamanaka, M | 1 |
| Kojima, K | 1 |
| Anzai, H | 1 |
| Numata, A | 1 |
| Kishimoto, T | 1 |
| Kanayama, HO | 1 |
| Sorrentino, R | 1 |
| Autore, G | 1 |
| Cirino, G | 1 |
| d'Emmanuele de Villa Bianca, R | 1 |
| Calignano, A | 1 |
| Vanasia, M | 1 |
| Alfieri, C | 1 |
| Sorrentino, L | 1 |
| Pinto, A | 1 |
3 other studies available for spironolactone and Muscle Relaxation
| Article | Year |
|---|---|
Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice.
Topics: Acetylcholine; Aldosterone; Animals; Caveolin 1; Eplerenone; Male; Mice; Mice, Knockout; Mineralocor | 2010 |
Effect of aldosterone on isolated human penile corpus cavernosum tissue.
Topics: Adult; Aged; Aldosterone; Humans; In Vitro Techniques; Male; Middle Aged; Mineralocorticoid Receptor | 2008 |
Effect of spironolactone and its metabolites on contractile property of isolated rat aorta rings.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Canrenoic Acid; Canrenone; In Vitro Techniques; | 2000 |