spironolactone has been researched along with Metabolic Diseases in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marzolla, V | 1 |
| Feraco, A | 1 |
| Limana, F | 1 |
| Kolkhof, P | 1 |
| Armani, A | 1 |
| Caprio, M | 1 |
| Thomas, M | 1 |
| Vidal, A | 1 |
| Bhattacharya, SK | 1 |
| Ahokas, RA | 1 |
| Sun, Y | 1 |
| Gerling, IC | 1 |
| Weber, KT | 1 |
| Dave-Sharma, S | 1 |
| Wilson, RC | 1 |
| Harbison, MD | 1 |
| Newfield, R | 1 |
| Azar, MR | 1 |
| Krozowski, ZS | 1 |
| Funder, JW | 1 |
| Shackleton, CH | 1 |
| Bradlow, HL | 1 |
| Wei, JQ | 1 |
| Hertecant, J | 1 |
| Moran, A | 1 |
| Neiberger, RE | 1 |
| Balfe, JW | 1 |
| Fattah, A | 1 |
| Daneman, D | 1 |
| Akkurt, HI | 1 |
| De Santis, C | 1 |
| New, MI | 1 |
| Maebashi, M | 1 |
| Yoshinaga, K | 1 |
| Miura, K | 1 |
| Goto, K | 1 |
| Katsushima, I | 1 |
4 other studies available for spironolactone and Metabolic Diseases
| Article | Year |
|---|---|
Class-specific responses of brown adipose tissue to steroidal and nonsteroidal mineralocorticoid receptor antagonists.
Topics: Adipose Tissue, Brown; Animals; Disease Models, Animal; Gene Expression Profiling; Insulin Resistanc | 2022 |
Zinc dyshomeostasis in rats with aldosteronism. Response to spironolactone.
Topics: Aldosterone; Animals; Coronary Vessels; Disease Models, Animal; Feces; Fibrosis; Homeostasis; Hypera | 2007 |
Examination of genotype and phenotype relationships in 14 patients with apparent mineralocorticoid excess.
Topics: Adolescent; Child; Child, Preschool; Female; Genes, Recessive; Genotype; Growth Disorders; Humans; H | 1998 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz | 1969 |