spironolactone has been researched along with Memory Disorders in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albernaz-Mariano, KA | 1 |
| Demarchi Munhoz, C | 1 |
| Achterberg, EJ | 1 |
| Trezza, V | 1 |
| Vanderschuren, LJ | 1 |
| Maćkowiak, M | 1 |
| Grzegorzewska, M | 1 |
| Budziszewska, B | 1 |
| Chocyk, A | 1 |
| Hess, G | 1 |
| Wedzony, K | 1 |
| Cornelisse, S | 1 |
| Joëls, M | 1 |
| Smeets, T | 1 |
| Khaksari, M | 1 |
| Rashidy-Pour, A | 1 |
| Vafaei, AA | 1 |
1 trial available for spironolactone and Memory Disorders
| Article | Year |
|---|---|
A randomized trial on mineralocorticoid receptor blockade in men: effects on stress responses, selective attention, and memory.
Topics: Adolescent; Adult; Attention; Cognition Disorders; Double-Blind Method; Humans; Hypothalamo-Hypophys | 2011 |
4 other studies available for spironolactone and Memory Disorders
| Article | Year |
|---|---|
The infralimbic mineralocorticoid blockage prevents the stress-induced impairment of aversive memory extinction in rats.
Topics: Animals; Corticosterone; Fear; Glucocorticoids; Male; Memory Disorders; Mineralocorticoids; Rats; Ra | 2022 |
Glucocorticoid receptor antagonism disrupts the reconsolidation of social reward-related memories in rats.
Topics: Analysis of Variance; Animals; Cannabinoid Receptor Antagonists; Conditioning, Operant; Dizocilpine | 2014 |
Cocaine decreases the expression of PSA-NCAM protein and attenuates long-term potentiation via glucocorticoid receptors in the rat dentate gyrus.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cocaine; Cocaine-Related Disorders; Cort | 2008 |
Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats.
Topics: Animals; Anisomycin; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Drug Admini | 2007 |