spironolactone has been researched along with MS (Multiple Sclerosis) in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simon, O | 2 |
| Mertin, J | 4 |
| Brass, B | 1 |
| Koczorek, KR | 1 |
| Backmund, H | 1 |
| Schmiedek, P | 1 |
| Winnewisser, M | 1 |
| Theml, H | 1 |
| Begemann, H | 1 |
4 other studies available for spironolactone and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
[EEG changes following spirolactone treatment (author's transl)].
Topics: Aldosterone; Brain Edema; Canrenoic Acid; Electroencephalography; Encephalitis; Female; Humans; Male | 1978 |
[Pilot study on the efficacy of high doses of aldosterone and spirolactone derivatives in the treatment of multiple sclerosis].
Topics: Adult; Aldosterone; Blood Pressure Determination; Body Weight; Chronic Disease; Electrocardiography; | 1972 |
Disturbances of electrical activity of the brain induced by the spirolactone derivative potassium canrenoate.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Animals; Brain; Brain Edema; Cortical Synchroniza | 1973 |
[PHA-stimulation of blood lymphocytes in patients with multiple sclerosis during combined therapy with aldosterone and spirolactone derivatives].
Topics: Aldosterone; DNA; Humans; Lectins; Lymphocyte Activation; Multiple Sclerosis; Radioisotopes; Spirono | 1973 |