spironolactone has been researched along with Local Neoplasm Recurrence in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile." | 7.96 | Spironolactone use does not increase the risk of female breast cancer recurrence: A retrospective analysis. ( Bovonratwet, P; Friedman, AJ; Gu, A; Moawad, G; Silverberg, JI; Wei, C, 2020) |
| "Retrospective analysis of 63 women with hyperandrogenic skin symptoms due to polycystic ovary syndrome (PCOS), treated with spironolactone for at least 6 months as first-line treatment." | 4.31 | Long-Lasting Effects of Spironolactone after its Withdrawal in Patients with Hyperandrogenic Skin Disorders. ( Andrisani, A; Armanini, D; Barbot, M; Beggiao, F; Belloni Fortina, A; Bordin, L; Ceccato, F; Donà, G; Keiko Vedolin, C; Orlando, G; Ragazzi, E; Sabbadin, C; Scaroni, C, 2023) |
| "Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile." | 3.96 | Spironolactone use does not increase the risk of female breast cancer recurrence: A retrospective analysis. ( Bovonratwet, P; Friedman, AJ; Gu, A; Moawad, G; Silverberg, JI; Wei, C, 2020) |
| "The spironolactone is a diuretic of potassium savings." | 1.36 | [PSA and spironolactone]. ( Coulange, C; Delaporte, V; Deturmeny, J; Lechevallier, E; Maurin, C; Rybikowski, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sabbadin, C | 1 |
| Beggiao, F | 1 |
| Keiko Vedolin, C | 1 |
| Orlando, G | 1 |
| Ragazzi, E | 1 |
| Ceccato, F | 1 |
| Barbot, M | 1 |
| Bordin, L | 1 |
| Donà, G | 1 |
| Andrisani, A | 1 |
| Belloni Fortina, A | 1 |
| Scaroni, C | 1 |
| Armanini, D | 1 |
| Wei, C | 1 |
| Bovonratwet, P | 1 |
| Gu, A | 1 |
| Moawad, G | 1 |
| Silverberg, JI | 1 |
| Friedman, AJ | 1 |
| Heymann, WR | 1 |
| Rybikowski, S | 1 |
| Maurin, C | 1 |
| Deturmeny, J | 1 |
| Delaporte, V | 1 |
| Lechevallier, E | 1 |
| Coulange, C | 1 |
| Carmona-Bayonas, A | 1 |
| Soler, IO | 1 |
| Gómez, FI | 1 |
| Billalabeitia, EG | 1 |
| Saura, HP | 1 |
| Tafalla, MS | 1 |
| Díaz, MP | 1 |
| Stephens, RL | 1 |
| Hoogstraten, B | 1 |
| Haas, C | 1 |
| Clark, G | 1 |
1 trial available for spironolactone and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Pancreatic cancer treated with carmustine, fluorouracil, and spironolactone: a randomized study.
Topics: Adult; Carmustine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Middle Aged; Neopl | 1978 |
5 other studies available for spironolactone and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Long-Lasting Effects of Spironolactone after its Withdrawal in Patients with Hyperandrogenic Skin Disorders.
Topics: Female; Hirsutism; Humans; Neoplasm Recurrence, Local; Polycystic Ovary Syndrome; Quality of Life; R | 2023 |
Spironolactone use does not increase the risk of female breast cancer recurrence: A retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Alopecia; Breast Neoplasms; Databases, Factual; Female; Humans; Midd | 2020 |
Spironolactone and breast cancer: Fear not!
Topics: Breast Neoplasms; Fear; Female; Hirsutism; Humans; Neoplasm Recurrence, Local; Retrospective Studies | 2020 |
[PSA and spironolactone].
Topics: Aged; Androgen Antagonists; Humans; Male; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Pro | 2010 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang | 2007 |