spironolactone has been researched along with Liver Cirrhosis, Biliary in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatic hydrothorax is defined as a pleural effusion in patients with liver cirrhosis without primary cardiac, pulmonary or pleural disease." | 1.39 | A 62-year-old female patient with left-sided pleural effusion. ( Alhaji, M; Sadikot, RT, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alhaji, M | 1 |
| Sadikot, RT | 1 |
| Eaves, ER | 1 |
| Korman, MG | 1 |
| Solymoss, B | 1 |
| Zsigmond, G | 1 |
3 other studies available for spironolactone and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
A 62-year-old female patient with left-sided pleural effusion.
Topics: Biopsy; Drug Therapy, Combination; Female; Furosemide; Humans; Hydrothorax; Liver Cirrhosis, Biliary | 2013 |
Cholestyramine induced hyperchloremic metabolic acidosis.
Topics: Acidosis; Aged; Chlorides; Cholestyramine Resin; Female; Humans; Hydrogen-Ion Concentration; Liver C | 1984 |
Effect of microsomal enzyme inducers on the liver changes produced by common bile-duct ligature.
Topics: Animals; Bilirubin; Common Bile Duct; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme | 1974 |