spironolactone has been researched along with Libman-Sacks Disease in 9 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day." | 7.74 | Hydroxychloroquine-induced hyperpigmentation: the staining pattern. ( Ferringer, T; Lountzis, NI; Puri, PK; Tyler, W, 2008) |
| " However, our recommendation against the use of combined oral contraceptive pills and in favor of spironolactone for the treatment of acne, in the setting of LE, received a satisfactory grading (grade A)." | 5.05 | The Safe Management of Acne Vulgaris in Lupus Erythematosus: A Systematic Review with Evidence-Based Treatment Recommendations. ( Forouzandeh, M; Maderal, AD, 2020) |
| "We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day." | 3.74 | Hydroxychloroquine-induced hyperpigmentation: the staining pattern. ( Ferringer, T; Lountzis, NI; Puri, PK; Tyler, W, 2008) |
| "These features were consistent with the Gitelman syndrome." | 1.56 | Systemic lupus erythematosus complicated by a Gitelman-like syndrome in an 8-year-old girl. ( Barathidasan, GS; Dhandapany, G; Ganesh, RN; Karunakar, P; Krishnamurthy, S; Rajendran, R; Ramamoorthy, JG; Ramya, K, 2020) |
| "A case of systemic lupus erythematosus (SLE) associated with fever, heart failure, and left ventricular (LV) aneurysm is reported." | 1.29 | Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus. ( Caldarulo, M; Frustaci, A; Gentiloni, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Forouzandeh, M | 1 |
| Maderal, AD | 1 |
| Barathidasan, GS | 1 |
| Krishnamurthy, S | 1 |
| Karunakar, P | 1 |
| Rajendran, R | 1 |
| Ramya, K | 1 |
| Dhandapany, G | 1 |
| Ramamoorthy, JG | 1 |
| Ganesh, RN | 1 |
| Puri, PK | 1 |
| Lountzis, NI | 1 |
| Tyler, W | 1 |
| Ferringer, T | 1 |
| Katayama, A | 1 |
| Otsuka, F | 1 |
| Tanabe, K | 1 |
| Tsukamoto, N | 1 |
| Yamanaka, R | 1 |
| Matsumoto, Y | 1 |
| Nasu, Y | 1 |
| Makino, H | 1 |
| SMITH, FG | 1 |
| LITMAN, N | 1 |
| LATTA, H | 1 |
| Frustaci, A | 1 |
| Gentiloni, N | 1 |
| Caldarulo, M | 1 |
| Uddin, MS | 1 |
| Lynfield, YL | 1 |
| Grosberg, SJ | 1 |
| Stiefler, R | 1 |
| Berbis, P | 1 |
| Vernay-Vaisse, C | 1 |
| Privat, Y | 1 |
| Neuberg, R | 1 |
1 review available for spironolactone and Libman-Sacks Disease
| Article | Year |
|---|---|
The Safe Management of Acne Vulgaris in Lupus Erythematosus: A Systematic Review with Evidence-Based Treatment Recommendations.
Topics: Acne Vulgaris; Contraceptives, Oral, Combined; Dermatologic Agents; Humans; Lupus Erythematosus, Sys | 2020 |
8 other studies available for spironolactone and Libman-Sacks Disease
| Article | Year |
|---|---|
Systemic lupus erythematosus complicated by a Gitelman-like syndrome in an 8-year-old girl.
Topics: Alkalosis; Child; Cyclophosphamide; Drug Therapy, Combination; Female; Gitelman Syndrome; Humans; Hy | 2020 |
Hydroxychloroquine-induced hyperpigmentation: the staining pattern.
Topics: Aged; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents | 2008 |
Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Angiomyolipoma; Antihyperten | 2011 |
LUPUS GLOMERULONEPHRITIS. THE EFFECT OF LARGE DOSES OF CORTICOSTEROIDS ON RENAL FUNCTION AND RENAL LESIONS IN TWO CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Cortisone; Drug Therapy; Glomerulonephritis; Guanethidine; Hydr | 1965 |
Acute myocarditis and left ventricular aneurysm as presentations of systemic lupus erythematosus.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Cardiac Output, Low; Diuretics; Endocarditis; Fever; | 1996 |
Cutaneous reaction to spironolactone resembling lupus erythematosus.
Topics: Diagnosis, Differential; Drug Eruptions; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; S | 1979 |
[Subacute cutaneous lupus observed during treatment with thiazide diuretics].
Topics: Aged; Benzothiadiazines; Diuretics; Drug Combinations; Female; Humans; Lupus Erythematosus, Systemic | 1986 |
Immunosuppression and plasmocytoma of the cervix.
Topics: Adult; Azathioprine; Diabetes Complications; Female; Furosemide; Humans; Immunosuppression Therapy; | 1974 |