spironolactone has been researched along with Kidney Stones in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We believe that primary hyperaldosteronism was a major pathogenetic factor in the formation of renal calculi since the increased urinary excretion of Ca++ and uric acid noted at onset declined following a short-term spironolactone administration and remission from renal calculi has persisted following initial nephrolithotomy and continued spironolactone therapy, which also corrected hypertension and hypokalemia, a hallmark of this disorder." | 1.29 | Renal calculi in primary hyperaldosteronism. ( Kabadi, UM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kabadi, UM | 1 |
| Müller-Berghaus, J | 1 |
| Homoki, J | 1 |
| Michalk, DV | 1 |
| Querfeld, U | 1 |
2 other studies available for spironolactone and Kidney Stones
| Article | Year |
|---|---|
Renal calculi in primary hyperaldosteronism.
Topics: Humans; Hyperaldosteronism; Kidney Calculi; Male; Middle Aged; Nephrostomy, Percutaneous; Spironolac | 1995 |
Diagnosis and treatment of a child with the syndrome of apparent mineralocorticoid excess type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Failure to Thrive; Female; Fetal Growth Retardation; Humans; | 1996 |