spironolactone has been researched along with Kidney Neoplasms in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone treatment and K-RAS suppression both led to a reduction in cell number in vitro." | 1.40 | Evidence for aldosterone-dependent growth of renal cell carcinoma. ( Bray, S; Christie, L; Fleming, S; Galbraith, S; King, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| King, S | 1 |
| Bray, S | 1 |
| Galbraith, S | 1 |
| Christie, L | 1 |
| Fleming, S | 1 |
| Feldman, RD | 1 |
| Ding, Q | 1 |
| Hussain, Y | 1 |
| Limbird, LE | 1 |
| Pickering, JG | 1 |
| Gros, R | 1 |
| Hes, O | 1 |
| Benakova, K | 1 |
| Vanecek, T | 1 |
| Sima, R | 1 |
| Michal, M | 1 |
| Flanagan, MJ | 1 |
| McDonald, JH | 1 |
| Shionoiri, H | 1 |
| Hirawa, N | 1 |
| Ueda, S | 1 |
| Himeno, H | 1 |
| Gotoh, E | 1 |
| Noguchi, K | 1 |
| Fukamizu, A | 1 |
| Seo, MS | 1 |
| Murakami, K | 1 |
| Maebashi, M | 1 |
| Yoshinaga, K | 1 |
| Miura, K | 1 |
| Goto, K | 1 |
| Katsushima, I | 1 |
6 other studies available for spironolactone and Kidney Neoplasms
| Article | Year |
|---|---|
Evidence for aldosterone-dependent growth of renal cell carcinoma.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Biomarkers, Tumor; Carcinoma, Renal Cell; Cell L | 2014 |
Aldosterone mediates metastatic spread of renal cancer via the G protein-coupled estrogen receptor (GPER).
Topics: Aldosterone; Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Kid | 2016 |
Clear cell type of renal cell carcinoma with numerous hyaline globules: a diagnostic pitfall.
Topics: Amino Acid Sequence; Base Sequence; Carcinoma, Renal Cell; Cytoplasm; DNA Primers; DNA, Neoplasm; Fr | 2005 |
Heterotopic adrenocortical adenoma producing primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Diagnosis, Differential; Diet, Sodium-Restricted; Female; H | 1967 |
Renin gene expression in the adrenal and kidney of patients with primary aldosteronism.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Carcinoma, Renal Cell; Gene Ex | 1992 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz | 1969 |