spironolactone and Intraocular Pressure
spironolactone has been researched along with Intraocular Pressure in 8 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Intraocular Pressure: The pressure of the fluids in the eye.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"In order to eliminate a previously reported stimulation of aqueous humor production by aldosterone, 22 glaucoma patients were treated for two weeks with 200 mg Spironolactone daily." | 7.66 | [Effect of spironolactone on intraocular pressure in glaucoma patients]. ( Witzmann, R, 1980) |
"Aldosterone was administered via an osmotic minipump that was implanted subcutaneously into the mid-scapular region." | 5.39 | Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. ( Fujita, T; Hirooka, K; Itano, T; Nakamura, T; Nishiyama, A; Nitta, E; Shiraga, F; Tenkumo, K, 2013) |
"Aldosterone was administered via an osmotic minipump that was implanted subcutaneously into the mid-scapular region." | 1.39 | Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. ( Fujita, T; Hirooka, K; Itano, T; Nakamura, T; Nishiyama, A; Nitta, E; Shiraga, F; Tenkumo, K, 2013) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (87.50) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Nitta, E | 1 |
Hirooka, K | 1 |
Tenkumo, K | 1 |
Fujita, T | 1 |
Nishiyama, A | 1 |
Nakamura, T | 1 |
Itano, T | 1 |
Shiraga, F | 1 |
BERNSTEIN, HN | 1 |
WISTRAND, PJ | 1 |
Cole, DF | 1 |
Sevcik, J | 1 |
Pullmann, R | 1 |
Pitiová, G | 1 |
Witzmann, R | 1 |
Marone, C | 1 |
Beretta-Piccoli, C | 1 |
Weidmann, P | 1 |
Watillon, M | 1 |
Robe-Vanwyck, A | 1 |
Other Studies
8 other studies available for spironolactone and Intraocular Pressure
Article | Year |
---|---|
Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma.
Topics: Aldosterone; Animals; Apoptosis; Cell Survival; Glaucoma; Intraocular Pressure; Male; Mineralocortic | 2013 |
ADRENAL CORTICOSTEROIDS AND INTRAOCULAR PRESSURE.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Intraocular Pressu | 1964 |
INTRAOCULAR PRESSURE AND RESISTANCE TO AQUEOUS OUTFLOW. EFFECTS OF CARBONIC ANHYDRASE INHIBITION, SALT DEPLETION, ADRENALECTOMY AND FLUDROCORTISONE.
Topics: Acetazolamide; Adrenalectomy; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydr | 1964 |
REDUCTION IN AQUEOUS HUMOUR FORMATION AS CAUSED BY IODATE, SPIROLACTONE, AND POLYPHLORETIN PHOSPHATE.
Topics: Animals; Aqueous Humor; Biological Transport, Active; Blood-Aqueous Barrier; Body Water; Chlorides; | 1962 |
[Participation of aldosterone in pathogenesis of primary glaucoma (author's transl)].
Topics: Aldosterone; Glaucoma; Humans; Intraocular Pressure; Spironolactone | 1981 |
[Effect of spironolactone on intraocular pressure in glaucoma patients].
Topics: Glaucoma; Humans; Intraocular Pressure; Spironolactone | 1980 |
[Basis and clinical aspects of diuretic drug therapy].
Topics: Acetazolamide; Benzothiadiazines; Diuretics; Edema; Edema, Cardiac; Furosemide; Glaucoma; Humans; Hy | 1979 |
[Harmful effects of common drugs on the visual apparatus. Diuretics].
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Diuretics; Drug Synergism; Eye Diseases; Hum | 1972 |