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spironolactone and Intraocular Pressure

spironolactone has been researched along with Intraocular Pressure in 8 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"In order to eliminate a previously reported stimulation of aqueous humor production by aldosterone, 22 glaucoma patients were treated for two weeks with 200 mg Spironolactone daily."7.66[Effect of spironolactone on intraocular pressure in glaucoma patients]. ( Witzmann, R, 1980)
"Aldosterone was administered via an osmotic minipump that was implanted subcutaneously into the mid-scapular region."5.39Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. ( Fujita, T; Hirooka, K; Itano, T; Nakamura, T; Nishiyama, A; Nitta, E; Shiraga, F; Tenkumo, K, 2013)
"Aldosterone was administered via an osmotic minipump that was implanted subcutaneously into the mid-scapular region."1.39Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. ( Fujita, T; Hirooka, K; Itano, T; Nakamura, T; Nishiyama, A; Nitta, E; Shiraga, F; Tenkumo, K, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nitta, E1
Hirooka, K1
Tenkumo, K1
Fujita, T1
Nishiyama, A1
Nakamura, T1
Itano, T1
Shiraga, F1
BERNSTEIN, HN1
WISTRAND, PJ1
Cole, DF1
Sevcik, J1
Pullmann, R1
Pitiová, G1
Witzmann, R1
Marone, C1
Beretta-Piccoli, C1
Weidmann, P1
Watillon, M1
Robe-Vanwyck, A1

Other Studies

8 other studies available for spironolactone and Intraocular Pressure

ArticleYear
Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma.
    Cell death & disease, 2013, Jul-04, Volume: 4

    Topics: Aldosterone; Animals; Apoptosis; Cell Survival; Glaucoma; Intraocular Pressure; Male; Mineralocortic

2013
ADRENAL CORTICOSTEROIDS AND INTRAOCULAR PRESSURE.
    Eye, ear, nose & throat monthly, 1964, Volume: 43

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Intraocular Pressu

1964
INTRAOCULAR PRESSURE AND RESISTANCE TO AQUEOUS OUTFLOW. EFFECTS OF CARBONIC ANHYDRASE INHIBITION, SALT DEPLETION, ADRENALECTOMY AND FLUDROCORTISONE.
    Experimental eye research, 1964, Volume: 3

    Topics: Acetazolamide; Adrenalectomy; Animals; Aqueous Humor; Carbonic Anhydrase Inhibitors; Carbonic Anhydr

1964
REDUCTION IN AQUEOUS HUMOUR FORMATION AS CAUSED BY IODATE, SPIROLACTONE, AND POLYPHLORETIN PHOSPHATE.
    The British journal of ophthalmology, 1962, Volume: 46, Issue:5

    Topics: Animals; Aqueous Humor; Biological Transport, Active; Blood-Aqueous Barrier; Body Water; Chlorides;

1962
[Participation of aldosterone in pathogenesis of primary glaucoma (author's transl)].
    Ceskoslovenska oftalmologie, 1981, Volume: 37, Issue:2

    Topics: Aldosterone; Glaucoma; Humans; Intraocular Pressure; Spironolactone

1981
[Effect of spironolactone on intraocular pressure in glaucoma patients].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 176, Issue:3

    Topics: Glaucoma; Humans; Intraocular Pressure; Spironolactone

1980
[Basis and clinical aspects of diuretic drug therapy].
    Therapeutische Umschau. Revue therapeutique, 1979, Volume: 36, Issue:7

    Topics: Acetazolamide; Benzothiadiazines; Diuretics; Edema; Edema, Cardiac; Furosemide; Glaucoma; Humans; Hy

1979
[Harmful effects of common drugs on the visual apparatus. Diuretics].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 160, Issue:1

    Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Diuretics; Drug Synergism; Eye Diseases; Hum

1972
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