spironolactone has been researched along with Intestinal Diseases in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone pretreatment markedly reduced intestinal I/R-induced lung injury as indicated by histology and MDA and MPO levels." | 5.43 | Reduction of Acute Lung Injury by Administration of Spironolactone After Intestinal Ischemia and Reperfusion in Rats. ( Aktunc, E; Barut, F; Ozacmak, VH; Sayan-Ozacmak, H; Turan, I, 2016) |
| "Spironolactone is an antifibrotic medication commonly used in heart failure to reduce mortality." | 5.38 | Spironolactone and colitis: increased mortality in rodents and in humans. ( Gillespie, BW; Govani, SM; Higgins, PD; Johnson, LA; Joyce, JC; Waljee, AK, 2012) |
| "Spironolactone pretreatment markedly reduced intestinal I/R-induced lung injury as indicated by histology and MDA and MPO levels." | 1.43 | Reduction of Acute Lung Injury by Administration of Spironolactone After Intestinal Ischemia and Reperfusion in Rats. ( Aktunc, E; Barut, F; Ozacmak, VH; Sayan-Ozacmak, H; Turan, I, 2016) |
| "Spironolactone is an antifibrotic medication commonly used in heart failure to reduce mortality." | 1.38 | Spironolactone and colitis: increased mortality in rodents and in humans. ( Gillespie, BW; Govani, SM; Higgins, PD; Johnson, LA; Joyce, JC; Waljee, AK, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barut, F | 1 |
| Ozacmak, VH | 1 |
| Turan, I | 1 |
| Sayan-Ozacmak, H | 1 |
| Aktunc, E | 1 |
| Johnson, LA | 1 |
| Govani, SM | 1 |
| Joyce, JC | 1 |
| Waljee, AK | 1 |
| Gillespie, BW | 1 |
| Higgins, PD | 1 |
| Selye, H | 2 |
| Solymoss, B | 1 |
| Toth, S | 1 |
| Varga, S | 1 |
| Diner, WC | 1 |
5 other studies available for spironolactone and Intestinal Diseases
| Article | Year |
|---|---|
Reduction of Acute Lung Injury by Administration of Spironolactone After Intestinal Ischemia and Reperfusion in Rats.
Topics: Acute Lung Injury; Animals; Intestinal Diseases; Male; Rats; Rats, Wistar; Reperfusion Injury; Spiro | 2016 |
Spironolactone and colitis: increased mortality in rodents and in humans.
Topics: Animals; Clostridioides difficile; Clostridium Infections; Colitis; Crohn Disease; Female; Fibrosis; | 2012 |
Prevention of indomethacin-induced intestinal ulcers by various catatoxic steroids.
Topics: Adrenal Cortex Hormones; Animals; Antitoxins; Chemical Phenomena; Chemistry; Corticosterone; Ethyles | 1970 |
Protection by spironolactone and oxandrolone against chronic digitoxin or indomethacin intoxication.
Topics: Animals; Digitoxin; Drug Antagonism; Female; Indomethacin; Intestinal Diseases; Jejunum; Microsomes, | 1971 |
Small intestinal edema in cirrhosis: its disappearance with diuresis.
Topics: Edema; Humans; Hydrochlorothiazide; Hypoproteinemia; Intestinal Diseases; Liver Cirrhosis; Male; Mid | 1968 |