spironolactone has been researched along with Infant, Premature, Diseases in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Segar, JL | 1 |
| RAPPALLINI, C | 1 |
| MURTAGH, JJ | 1 |
| Kao, LC | 1 |
| Warburton, D | 1 |
| Cheng, MH | 1 |
| Cedeño, C | 1 |
| Platzker, AC | 1 |
| Keens, TG | 1 |
| Vachharajani, AJ | 1 |
| Shah, JK | 2 |
| Paes, BA | 1 |
| Atkinson, SA | 1 |
| McGee, C | 1 |
| Steele, BT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694] | 175 participants (Anticipated) | Observational | 2021-09-08 | Recruiting | |||
| Calciuric Effect and Cyclic Parenteral Nutrition in Preterm Infants[NCT00711763] | 1 participants (Actual) | Observational | 2008-07-31 | Terminated (stopped due to failure to recruit more patients and lack of supporting personnel.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for spironolactone and Infant, Premature, Diseases
| Article | Year |
|---|---|
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
1 trial available for spironolactone and Infant, Premature, Diseases
| Article | Year |
|---|---|
Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind crossover sequential trial.
Topics: Administration, Oral; Airway Resistance; Body Weight; Bronchopulmonary Dysplasia; Chlorothiazide; Cl | 1984 |
3 other studies available for spironolactone and Infant, Premature, Diseases
| Article | Year |
|---|---|
[The edema of the premature infant; action of spirolactone].
Topics: Child; Diuretics; Edema; Edetic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Pr | 1961 |
Ovarian cyst in a premature infant treated with spironolactone.
Topics: Diseases in Twins; Diuretics; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, | 2001 |
Mineral excretion in premature infants receiving various diuretic therapies.
Topics: Birth Weight; Bone Diseases, Metabolic; Diuretics; Drug Therapy, Combination; Female; Furosemide; Hu | 1988 |