spironolactone has been researched along with Infant, Newborn, Diseases in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Segar, JL | 1 |
| ISASA, FA | 1 |
| FLETCHER, CB | 1 |
| EAKIN, EL | 1 |
| ROTHMAN, PE | 1 |
| Inoue, K | 1 |
| Yamashita, F | 1 |
| Nagayama, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694] | 175 participants (Anticipated) | Observational | 2021-09-08 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for spironolactone and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
Neonatal diuretic therapy: furosemide, thiazides, and spironolactone.
Topics: Bronchopulmonary Dysplasia; Diuretics; Ductus Arteriosus, Patent; Furosemide; Humans; Infant, Newbor | 2012 |
3 other studies available for spironolactone and Infant, Newborn, Diseases
| Article | Year |
|---|---|
[DIAGNOSTIC AND THERAPEUTIC MANAGEMENT OF THE NEPHROTIC SYNDROMES OF INFANCY].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Blood Protein Disorders | 1963 |
FETAL ASCITES--LIVER GIANT-CELL TRANSFORMATION. REPORT OF A CASE WITH RECOVERY.
Topics: Ascites; Biopsy; Drainage; Exchange Transfusion, Whole Blood; Fetal Diseases; Humans; Hydrochlorothi | 1964 |
The clinical pattern & the causative factors of late edema observed in low birth weight infants.
Topics: Birth Weight; Blood Proteins; Dexamethasone; Edema; Female; Gestational Age; Humans; Hypoproteinemia | 1968 |