spironolactone has been researched along with Impotence in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Subsequently, gynecomastia developed as a side effect of spironolactone and digoxin treatment." | 3.75 | [A mourning case that referred with sexual identity disorder secondary to a general medical condition]. ( Ceri, O; Koçak, OM; Soykan, A; Tatlidil, E; Yilmaz, A, 2009) |
| "Therapy with spironolactone is often associated with estrogenlike side-effects, including impotence and gynecomastia in men and menstrual irregularity in women." | 3.65 | Spironolactone and endocrine dysfunction. ( , 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yilmaz, A | 1 |
| Ceri, O | 1 |
| Tatlidil, E | 1 |
| Koçak, OM | 1 |
| Soykan, A | 1 |
| Ménard, J | 1 |
| Moss, HB | 1 |
| Procci, WR | 1 |
| Zarren, HS | 1 |
| Black, PM | 1 |
| Esch, I | 1 |
| Placheta, P | 1 |
| Greenblatt, DJ | 1 |
| Koch-Weser, J | 1 |
1 trial available for spironolactone and Impotence
| Article | Year |
|---|---|
[Treatment of essential hypertension with spironolactone with reference to the plasma renin activity].
Topics: Blood Pressure; Body Weight; Clinical Trials as Topic; Erectile Dysfunction; Gastrointestinal Diseas | 1973 |
6 other studies available for spironolactone and Impotence
| Article | Year |
|---|---|
[A mourning case that referred with sexual identity disorder secondary to a general medical condition].
Topics: Bereavement; Depression; Digoxin; Erectile Dysfunction; Female; Gender Identity; Gynecomastia; Human | 2009 |
The 45-year story of the development of an anti-aldosterone more specific than spironolactone.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Chlorthalidone; Clinical Trials as Topic; Erectile | 2004 |
Sexual dysfunction associated with oral antihypertensive medication: a critical survey of the literature.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Erectile Dysfunction; Guanethidine; Humans; Hypertens | 1982 |
Unilateral gynecomastia and impotence during low-dose spironolactone administration in men.
Topics: Dose-Response Relationship, Drug; Erectile Dysfunction; Gynecomastia; Humans; Male; Middle Aged; Spi | 1975 |
Spironolactone and endocrine dysfunction.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Androgen Antagonists; Animals; Child, Presc | 1976 |
Gynecomastia and impotence: complications of spironolactone therapy.
Topics: Erectile Dysfunction; Gynecomastia; Humans; Male; Middle Aged; Spironolactone | 1973 |