spironolactone and Hypovolemic
spironolactone has been researched along with Hypovolemic in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Liver cirrhosis is associated to circulatory abnormalities leading to hypovolemia and stimulation of the renin-angiotensin-aldosterone system (RAAS)." | 1.91 | Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression. ( Alvarez de la Rosa, D; González-Alayón, C; Hernández, G; Hernández-Guerra, M; Porrini, E; Rodríguez-Rodríguez, AE; Serrano-Morillas, N; Vastola-Mascolo, A, 2023) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 1 (25.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Serrano-Morillas, N | 1 |
González-Alayón, C | 1 |
Vastola-Mascolo, A | 1 |
Rodríguez-Rodríguez, AE | 1 |
Hernández, G | 1 |
Porrini, E | 1 |
Hernández-Guerra, M | 1 |
Alvarez de la Rosa, D | 1 |
Shoemaker, JK | 3 |
Usselman, CW | 1 |
Rothwell, A | 1 |
Wong, SW | 1 |
Kimmerly, DS | 2 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes[NCT02362347] | 153 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Trials
3 trials available for spironolactone and Hypovolemic
Article | Year |
---|---|
Altered cortical activation patterns associated with baroreflex unloading following 24 h of physical deconditioning.
Topics: Adult; Analysis of Variance; Arterial Pressure; Autonomic Nervous System; Baroreflex; Bed Rest; Biom | 2012 |
Hypovolemia and MSNA discharge patterns: assessing and interpreting sympathetic responses.
Topics: Adult; Central Venous Pressure; Diuretics; Electrocardiography; Heart Rate; Humans; Hypovolemia; Low | 2003 |
Hypovolemia and neurovascular control during orthostatic stress.
Topics: Adult; Baroreflex; Blood Pressure; Brachial Artery; Diuretics; Heart Rate; Humans; Hypotension, Orth | 2002 |
Other Studies
1 other study available for spironolactone and Hypovolemic
Article | Year |
---|---|
Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression.
Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Gene Expression; Hypovolemia; Kidney; Liver | 2023 |