Page last updated: 2024-11-07

spironolactone and Hypovolemic

spironolactone has been researched along with Hypovolemic in 4 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Research Excerpts

ExcerptRelevanceReference
"Liver cirrhosis is associated to circulatory abnormalities leading to hypovolemia and stimulation of the renin-angiotensin-aldosterone system (RAAS)."1.91Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression. ( Alvarez de la Rosa, D; González-Alayón, C; Hernández, G; Hernández-Guerra, M; Porrini, E; Rodríguez-Rodríguez, AE; Serrano-Morillas, N; Vastola-Mascolo, A, 2023)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Serrano-Morillas, N1
González-Alayón, C1
Vastola-Mascolo, A1
Rodríguez-Rodríguez, AE1
Hernández, G1
Porrini, E1
Hernández-Guerra, M1
Alvarez de la Rosa, D1
Shoemaker, JK3
Usselman, CW1
Rothwell, A1
Wong, SW1
Kimmerly, DS2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes[NCT02362347]153 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for spironolactone and Hypovolemic

ArticleYear
Altered cortical activation patterns associated with baroreflex unloading following 24 h of physical deconditioning.
    Experimental physiology, 2012, Volume: 97, Issue:12

    Topics: Adult; Analysis of Variance; Arterial Pressure; Autonomic Nervous System; Baroreflex; Bed Rest; Biom

2012
Hypovolemia and MSNA discharge patterns: assessing and interpreting sympathetic responses.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:4

    Topics: Adult; Central Venous Pressure; Diuretics; Electrocardiography; Heart Rate; Humans; Hypovolemia; Low

2003
Hypovolemia and neurovascular control during orthostatic stress.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2

    Topics: Adult; Baroreflex; Blood Pressure; Brachial Artery; Diuretics; Heart Rate; Humans; Hypotension, Orth

2002

Other Studies

1 other study available for spironolactone and Hypovolemic

ArticleYear
Decaying kidney function during cirrhosis correlates with remodeling of distal colon aldosterone target gene expression.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Aldosterone; Animals; Colon; Epithelial Sodium Channels; Gene Expression; Hypovolemia; Kidney; Liver

2023
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