Page last updated: 2024-11-07

spironolactone and Hyponatremia

spironolactone has been researched along with Hyponatremia in 52 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" To investigate the effects of the addition of a vasopressin V(2) receptor antagonist, satavaptan, to 100mg spironolactone on ascites recurrence after a large volume paracentesis in patients with liver cirrhosis irrespective of the presence of hyponatraemia."9.14Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis. ( Angeli, P; Bernardi, M; Gines, P; Gow, P; Horsmans, Y; Minini, P; Watson, H; Wong, F, 2010)
"This study was designed to investigate the appropriateness and complications of the use of spironolactone for heart failure (HF) in clinical practice."9.10Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines. ( Agoston, I; Bozkurt, B; Knowlton, AA, 2003)
" We investigated the association of clinical variables and cardiovascular drugs, including furosemide, hydrochlorothiazide, spironolactone, and their doses, with the presence of hyponatremia at admission."7.96Furosemide and spironolactone doses and hyponatremia in patients with heart failure. ( Bušić, Ž; Čulić, V; Jurić Paić, M; Velat, I, 2020)
"This paper details the case of a 26-year-old woman with depletion syndrome and the effectiveness of her treatment with indomethacin."7.85Indomethacin therapy effective in a patient with depletion syndrome from secretory villous adenoma. ( Kagan, MD; Sangha, G; Schmidt, K, 2017)
"We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics."7.67Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986)
"To evaluate the role of the renin-angiotensin system and sodium depletion in the hypotensive response to 1-sarcosine-8-alanine-angiotensin II (saralasin), 15 male patients with essential hypertension were studied on a diet containing 120 mEq of sodium and 100 mEq of potassium per day."7.66Angiotensin II, plasma renin and sodium depletion as determinants of blood pressure response to saralasin in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1980)
"Spironolactone was evaluated as a diuretic in the therapy of six patients with chronic severe congestive heart failure, during which metabolic balance studies were performed."7.64EFFECT OF AN ALDOSTERONE ANTAGONIST (SPIRONOLACTONE) ON PATIENTS WITH SEVERE CONGESTIVE HEART FAILURE. ( CARRUTHERS, BM; LEDRAY, RD; MCINTOSH, HW; SERAGLIA, M; WALSH, GC, 1963)
" To investigate the effects of the addition of a vasopressin V(2) receptor antagonist, satavaptan, to 100mg spironolactone on ascites recurrence after a large volume paracentesis in patients with liver cirrhosis irrespective of the presence of hyponatraemia."5.14Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis. ( Angeli, P; Bernardi, M; Gines, P; Gow, P; Horsmans, Y; Minini, P; Watson, H; Wong, F, 2010)
"This study was designed to investigate the appropriateness and complications of the use of spironolactone for heart failure (HF) in clinical practice."5.10Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines. ( Agoston, I; Bozkurt, B; Knowlton, AA, 2003)
" We investigated the association of clinical variables and cardiovascular drugs, including furosemide, hydrochlorothiazide, spironolactone, and their doses, with the presence of hyponatremia at admission."3.96Furosemide and spironolactone doses and hyponatremia in patients with heart failure. ( Bušić, Ž; Čulić, V; Jurić Paić, M; Velat, I, 2020)
"This paper details the case of a 26-year-old woman with depletion syndrome and the effectiveness of her treatment with indomethacin."3.85Indomethacin therapy effective in a patient with depletion syndrome from secretory villous adenoma. ( Kagan, MD; Sangha, G; Schmidt, K, 2017)
"To determine if the administration of an angiotensin-converting enzyme inhibitor (ACEI) plus spironolactone caused hyperkalemia, hypermagnesemia, or hyponatremia in elderly small dogs with degenerative mitral valve disease (MVD)."3.74Influence of combined angiotensin-converting enzyme inhibitors and spironolactone on serum K+, Mg 2+, and Na+ concentrations in small dogs with degenerative mitral valve disease. ( Calvert, CA; Fallaw, TK; Rockwell, JE; Thomason, JD, 2007)
"We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics."3.67Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986)
"To evaluate the role of the renin-angiotensin system and sodium depletion in the hypotensive response to 1-sarcosine-8-alanine-angiotensin II (saralasin), 15 male patients with essential hypertension were studied on a diet containing 120 mEq of sodium and 100 mEq of potassium per day."3.66Angiotensin II, plasma renin and sodium depletion as determinants of blood pressure response to saralasin in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1980)
"In 8 out of 20 patients with chronic liver disease ascites was controlled with metolazone, 10 required additional amiloride or spironolactone to achieve control, and 2 were resistant to all diuretic therapy."3.65Use of metolazone in the treatment of ascites due to liver disease. ( Hillenbrand, P; Sherlock, S, 1971)
"Spironolactone was evaluated as a diuretic in the therapy of six patients with chronic severe congestive heart failure, during which metabolic balance studies were performed."3.64EFFECT OF AN ALDOSTERONE ANTAGONIST (SPIRONOLACTONE) ON PATIENTS WITH SEVERE CONGESTIVE HEART FAILURE. ( CARRUTHERS, BM; LEDRAY, RD; MCINTOSH, HW; SERAGLIA, M; WALSH, GC, 1963)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199036 (69.23)18.7374
1990's4 (7.69)18.2507
2000's7 (13.46)29.6817
2010's4 (7.69)24.3611
2020's1 (1.92)2.80

Authors

AuthorsStudies
Velat, I1
Bušić, Ž1
Jurić Paić, M1
Čulić, V1
Kagan, MD1
Schmidt, K1
Sangha, G1
Morris, MJ1
Na, ES1
Johnson, AK1
Wong, F1
Gines, P2
Watson, H1
Horsmans, Y1
Angeli, P1
Gow, P1
Minini, P1
Bernardi, M1
Salerno, F1
Cazzaniga, M1
Accordino, S1
Bozkurt, B1
Agoston, I1
Knowlton, AA1
FORLAND, M1
PULLMAN, TN1
CARRUTHERS, BM1
LEDRAY, RD1
SERAGLIA, M1
MCINTOSH, HW1
WALSH, GC1
STERNBERG, MS1
HAGEDORN, CW1
KALSER, MH1
ALBEAUX-FERNET, M1
ROMANI, JD1
CONTE, M1
FOUET, P1
JACOBS, C1
BAGROS, P1
ROYER, P1
DELAITRE, R1
MATHIEU, H1
GABILAN, JC1
RAYNAUD, C1
PASQUALINI, JR1
DEBRIS, P1
GERBEAUX, S1
HABIB, R1
MAHER, JF1
SCHREINER, GE1
Fujii, M1
Suto, H1
Goto, M1
Miki, Y1
Asai, N1
Shibata, H2
Thomason, JD1
Rockwell, JE1
Fallaw, TK1
Calvert, CA1
Handler, J1
Thananopavarn, C1
Golub, MS1
Eggena, P1
Barrett, JD1
Sambhi, MP1
Hirschl, MM1
Seidler, D1
Laggner, AN1
van Furth, WR1
Eelkman Rooda, SJ1
Schwinger, RH1
Lenaerts, A1
Codden, T1
Henry, JP1
Van Cauter, J1
Meunier, JC1
Ligny, G1
Taylor, JW1
Delavelle, F1
Becchio, J1
Fries, D1
Marone, C1
Beretta-Piccoli, C1
Weidmann, P1
Datey, KK1
Bhagat, SJ1
Barat, AK1
Surana, MC1
Gifford, RW1
Hagège, H1
Ink, O1
Ducreux, M1
Pelletier, G1
Buffet, C1
Etienne, JP1
Arroyo, V1
Badalamenti, S1
Greenberg, A1
Decaux, G1
Mols, P1
Cauchie, P1
Flamion, B1
Delwiche, F1
Sherlock, S4
Senewiratne, B3
Scott, A2
Walker, JG2
Wolf, LM1
Courtois, H1
Schrub, JC1
Raynaud, R1
Brochier, M1
Raynaud, P1
Fauchier, JP1
Greenblatt, DJ1
Koch-Weser, J1
Nitter-Hauge, S1
Brodwall, EK1
Rootwelt, K1
Dölle, W1
Paris, GL1
Macoul, KL1
Sánchez, A1
Anderton, JL1
Kincaid-Smith, P1
Reubi, FC1
Sobel, A1
Safar, M1
Milliez, P1
Hillenbrand, P1
Schmidt, P1
Rorive, G1
Christensen, BE1
Andrieu, J1
Lesueur, G1
Schwarzbach, W1
Haas, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study for the Prevention of Ascites (SPA): Comparison of Fixed Doses of SR121463B Versus Placebo in the Reduction of Recurrence of Cirrhotic Ascites[NCT00501384]Phase 2151 participants (Actual)Interventional2004-04-30Completed
The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients With Ascites and Activation of Sympathetic Nervous System: a Randomized Double-Blind Placebo Controlled Study.[NCT00356226]64 participants Interventional2000-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for spironolactone and Hyponatremia

ArticleYear
[Corticosterone-producing adrenal tumor].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Corticosterone; Diagnosis, Differential; Humans; Hy

2006
[Deoxycorticosterone-producing adrenal tumor].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antineoplastic Agents, Hormonal; Desoxycorticosterone; Diagn

2006
Well tolerated spironolactone-related hyponatremia.
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:4

    Topics: Aged, 80 and over; Diuretics; Female; Humans; Hyponatremia; Risk Factors; Spironolactone

2008
[Value of diuretics and aldosterone antagonists in the treatment of heart failure].
    Deutsche medizinische Wochenschrift (1946), 1999, Sep-24, Volume: 124 Suppl 2

    Topics: Benzothiadiazines; Diuretics; Drug Interactions; Drug Resistance; Heart Failure; Humans; Hyponatremi

1999
[Depletion therapy of chronic congestive heart failure].
    Revista espanola de cardiologia, 1968, Volume: 21, Issue:2

    Topics: Bloodletting; Carbonic Anhydrase Inhibitors; Chlorides; Diet, Sodium-Restricted; Digitalis Glycoside

1968
Diuretics. II. Clinical considerations.
    Drugs, 1971, Volume: 1, Issue:2

    Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I

1971
Combination diuretic drug therapy.
    Cardiovascular clinics, 1971, Volume: 2, Issue:3

    Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemid

1971

Trials

4 trials available for spironolactone and Hyponatremia

ArticleYear
Effects of a selective vasopressin V2 receptor antagonist, satavaptan, on ascites recurrence after paracentesis in patients with cirrhosis.
    Journal of hepatology, 2010, Volume: 53, Issue:2

    Topics: Aged; Antidiuretic Hormone Receptor Antagonists; Ascites; Combined Modality Therapy; Creatinine; Diu

2010
Complications of inappropriate use of spironolactone in heart failure: when an old medicine spirals out of new guidelines.
    Journal of the American College of Cardiology, 2003, Jan-15, Volume: 41, Issue:2

    Topics: Aged; Guideline Adherence; Heart Failure; Humans; Hyperkalemia; Hyponatremia; Hypotension; Male; Mid

2003
[Use of demeclotetracycline in the treatment of hyponatremia in cirrhotic ascitis].
    La Nouvelle presse medicale, 1977, Jan-15, Volume: 6, Issue:21

    Topics: Adult; Aged; Ascites; Clinical Trials as Topic; Demeclocycline; Drug Therapy, Combination; Edema; Fe

1977
[Treatment of ascites in patients with liver cirrhosis without neither hyponatremia nor renal insufficiency. Results of a randomized study comparing diuretics and punctures compensated by albumin].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:10

    Topics: Aged; Albumins; Ascites; Combined Modality Therapy; Drug Therapy, Combination; Female; Furosemide; H

1992

Other Studies

41 other studies available for spironolactone and Hyponatremia

ArticleYear
Furosemide and spironolactone doses and hyponatremia in patients with heart failure.
    BMC pharmacology & toxicology, 2020, 08-03, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Diuretics; Female; Furosemide; Heart Failure; Hospitalization; Humans; Hydr

2020
Indomethacin therapy effective in a patient with depletion syndrome from secretory villous adenoma.
    BMJ case reports, 2017, Feb-10, Volume: 2017

    Topics: Adenoma, Villous; Adult; Cyclooxygenase Inhibitors; Diuretics; Drug Therapy, Combination; Female; Hu

2017
Mineralocorticoid receptor antagonism prevents hedonic deficits induced by a chronic sodium appetite.
    Behavioral neuroscience, 2010, Volume: 124, Issue:2

    Topics: Aldosterone; Animals; Appetite; Captopril; Desoxycorticosterone; Drug Interactions; Furosemide; Hypo

2010
May vaptans contribute to the treatment of refractory ascites?
    Journal of hepatology, 2010, Volume: 53, Issue:2

    Topics: Antidiuretic Hormone Receptor Antagonists; Ascites; Combined Modality Therapy; Diuretics; Dose-Respo

2010
Electrolyte complications of drug therapy.
    The Medical clinics of North America, 1963, Volume: 47

    Topics: Alkalosis; Anatomy; Carbonic Anhydrases; Diuretics; Electrolytes; Estrogens; Humans; Hypercalcemia;

1963
EFFECT OF AN ALDOSTERONE ANTAGONIST (SPIRONOLACTONE) ON PATIENTS WITH SEVERE CONGESTIVE HEART FAILURE.
    Canadian Medical Association journal, 1963, Sep-28, Volume: 89

    Topics: Aldosterone; Antihypertensive Agents; Body Fluids; Diuresis; Diuretics; Female; Geriatrics; Heart Fa

1963
THE USE OF SPIRONOLACTONE AND LARGE DOSES OF STEROIDS IN THE TREATMENT OF ASCITES OF LIVER DISEASE.
    Southern medical journal, 1963, Volume: 56

    Topics: Adrenal Cortex Hormones; Ascites; Chlorothiazide; Diuresis; Hepatic Encephalopathy; Humans; Hyponatr

1963
[LIMITS OF TREATMENT OF CIRRHOSIS WITH DIURETICS (SALDIURETICS AND ALDOSTERONE ANTAGONISTS)].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1963, Nov-29, Volume: 114

    Topics: Ascites; Diuretics; Humans; Hyperkalemia; Hyponatremia; Liver Cirrhosis; Mineralocorticoid Receptor

1963
[WATER RETENTION IN CIRRHOTICS. PHYSIOPATHOLOGICAL DATA AND THERAPEUTIC RESULTS].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1963, Nov-29, Volume: 114

    Topics: Ascites; Edema; Heart Failure; Humans; Hypokalemia; Hyponatremia; Liver Cirrhosis; Mineralocorticoid

1963
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
    Vie medicale (Paris, France : 1920), 1964, Volume: 45

    Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics;

1964
[CHRONIC IDIOPATHIC HYPOKALEMIA WITH HYPERKALIURIA IN CHILDREN].
    Revue francaise d'etudes cliniques et biologiques, 1964, Volume: 9

    Topics: Adrenal Glands; Aldosterone; Blood Platelet Disorders; Blood Platelets; Child; Corticosterone; Dwarf

1964
STUDIES ON ETHACRYNIC ACID IN PATIENTS WITH REFRACTORY EDEMA.
    Annals of internal medicine, 1965, Volume: 62

    Topics: Alkalosis; Blood; Chlorides; Creatine; Creatinine; Diuretics; Drug Therapy; Edema; Ethacrynic Acid;

1965
[Water-electrolyte imbalance: Reality in diagnosis and therapy (discussion)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, May-10, Volume: 95, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Diagnosis, Differential; Extracellular Fluid; Humans; Hypercalcemia

2006
Influence of combined angiotensin-converting enzyme inhibitors and spironolactone on serum K+, Mg 2+, and Na+ concentrations in small dogs with degenerative mitral valve disease.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2007, Volume: 9, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diuretics; Dog Diseases; Dogs; Drug Interactions;

2007
Angiotensin II, plasma renin and sodium depletion as determinants of blood pressure response to saralasin in essential hypertension.
    Circulation, 1980, Volume: 61, Issue:5

    Topics: Adult; Aged; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combina

1980
Spironolactone-associated hyponatremic coma.
    Nephron, 1994, Volume: 67, Issue:4

    Topics: Aged; Aged, 80 and over; Coma; Female; Humans; Hyponatremia; Spironolactone

1994
[A little less sodium is not without hazard].
    Nederlands tijdschrift voor geneeskunde, 1993, Jan-09, Volume: 137, Issue:2

    Topics: Diagnosis, Differential; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged

1993
[Biological factors influencing response to diuretics in patients with cirrhosis and ascites].
    Gastroenterologie clinique et biologique, 2001, Volume: 25, Issue:3

    Topics: Aldosterone; Ascites; Diuretics; Female; Furosemide; Glomerular Filtration Rate; Humans; Hyperkalemi

2001
Mental symptoms and electrolyte imbalance.
    The Australian and New Zealand journal of psychiatry, 1979, Volume: 13, Issue:2

    Topics: Aged; Chlorine; Cognition Disorders; Confusion; Depression; Diuretics; Female; Humans; Hyponatremia;

1979
[Basis and clinical aspects of diuretic drug therapy].
    Therapeutische Umschau. Revue therapeutique, 1979, Volume: 36, Issue:7

    Topics: Acetazolamide; Benzothiadiazines; Diuretics; Edema; Edema, Cardiac; Furosemide; Glaucoma; Humans; Hy

1979
Management of intractable heart failure with hyponatremia.
    The Indian journal of chest diseases & allied sciences, 1978, Volume: 20, Issue:1

    Topics: Adult; Aged; Dexamethasone; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hy

1978
A guide to the practical use of diuretics.
    JAMA, 1976, Apr-26, Volume: 235, Issue:17

    Topics: Administration, Oral; Diuretics; Edema; Furosemide; Humans; Hypercalcemia; Hyperglycemia; Hypertensi

1976
Refractory ascites: definition and mechanism.
    Minerva medica, 1987, May-31, Volume: 78, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Ascites; Diet, Sodium-Restricted; Diuretics; Drainage; Drug

1987
What's new in diuretic therapy.
    American family physician, 1986, Volume: 33, Issue:5

    Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci

1986
Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea.
    Nephron, 1986, Volume: 44, Issue:4

    Topics: Adult; Ascites; Body Weight; Creatinine; Drug Therapy, Combination; Edema; Furosemide; Humans; Hypon

1986
Complications of diuretic therapy in hepatic cirrhosis.
    Lancet (London, England), 1966, May-14, Volume: 1, Issue:7446

    Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia;

1966
Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver.
    Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534

    Topics: Adult; Ascites; Bicarbonates; Creatinine; Diuretics; Ethacrynic Acid; Furosemide; Guanidines; Humans

1968
[Hypercalcemia and thiazides].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1973, Apr-08, Volume: 49, Issue:17

    Topics: Benzothiadiazines; Diabetic Angiopathies; Diuretics; Drug Synergism; Edema; Female; Humans; Hypercal

1973
[Hyperkalemias in cardiac patients].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1974, Oct-08, Volume: 50, Issue:40

    Topics: Acidosis; Acute Kidney Injury; Adult; Aged; Arrhythmias, Cardiac; Digitalis Glycosides; Diuretics; F

1974
Adverse reactions to spironolactone. A report from the Boston Collaborative Drug Surveillance Program.
    JAMA, 1973, Jul-02, Volume: 225, Issue:1

    Topics: Adult; Aged; Blood Urea Nitrogen; Coma; Dehydration; Diarrhea; Female; Gynecomastia; Headache; Heart

1973
[Hyponatremia syndrome in congestive heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, May-10, Volume: 93, Issue:13

    Topics: Female; Furosemide; Heart Failure; Humans; Hyponatremia; Middle Aged; Sodium; Spironolactone; Syndro

1973
[Pathogenesis and therapy of ascites in liver cirrhosis].
    Der Internist, 1966, Volume: 7, Issue:1

    Topics: Acid-Base Equilibrium; Alkalosis; Ascites; Deficiency Diseases; Diet; Diuresis; Diuretics; Furosemid

1966
Reversible bullous retinal detachment in chronic renal disease.
    American journal of ophthalmology, 1969, Volume: 67, Issue:2

    Topics: Adult; Angiography; Diet; Female; Fluorescence; Humans; Hydrochlorothiazide; Hypertension, Renal; Hy

1969
[Water-sodium depletion and clonidine in severe arterial hypertension].
    Maroc medical, 1972, Volume: 52, Issue:556

    Topics: Adult; Antihypertensive Agents; Body Weight; Clonidine; Creatinine; Drug Synergism; Electrocardiogra

1972
Use of metolazone in the treatment of ascites due to liver disease.
    British medical journal, 1971, Oct-30, Volume: 4, Issue:5782

    Topics: Adult; Ascites; Chlorides; Chronic Disease; Diuretics; Female; Hepatic Encephalopathy; Humans; Hypok

1971
[Diuresis and diuretics].
    Wiener klinische Wochenschrift, 1971, Jun-25, Volume: 83, Issue:25

    Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder

1971
The complications of diuretic therapy in patients with cirrhosis.
    Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2

    Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph

1966
[Apropos of certain secondary effects of diuretics].
    Acta clinica Belgica, 1968, Volume: 23, Issue:1

    Topics: Blood Volume; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hyperkalemia; Hypon

1968
[Metyrapone incombination with spironolactone and prednisone in the therapy of severe edema].
    Nordisk medicin, 1968, Aug-15, Volume: 80, Issue:33

    Topics: Aged; Brain Edema; Drug Synergism; Edema; Female; Humans; Hyperkalemia; Hyponatremia; Metyrapone; Mi

1968
[Diuretics in cirrhosis. Accidents. Indications].
    La Presse medicale, 1969, Mar-29, Volume: 77, Issue:16

    Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic

1969
[Saluretic therapy and insulin resistance in diabetes mellitus].
    Medizinische Klinik, 1966, Dec-23, Volume: 61, Issue:51

    Topics: Aged; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Female; Furosemide; Humans; Hyponatr

1966