spironolactone has been researched along with Hypocalcemia in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperaldosteronism due to klotho deficiency results in vascular calcification, which can be mitigated by spironolactone treatment." | 4.90 | Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease. ( Fahrleitner-Pammer, A; Gaksch, M; Grübler, M; Kienreich, K; Kraigher-Krainer, E; März, W; Mrak, P; Pieske, B; Pilz, S; Ritz, E; Rus-Machan, J; Tomaschitz, A; Toplak, H; Verheyen, N, 2014) |
| " Thus we diagnosed pseudoaldosteronism that was related to the long-term use of glycyrrhizin." | 1.36 | Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemia. ( Asano, Y; Homma, S; Inaba, T; Kusano, E; Muto, S; Onishi, A; Shuto, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomaschitz, A | 1 |
| Ritz, E | 1 |
| Pieske, B | 1 |
| Rus-Machan, J | 1 |
| Kienreich, K | 1 |
| Verheyen, N | 1 |
| Gaksch, M | 1 |
| Grübler, M | 1 |
| Fahrleitner-Pammer, A | 1 |
| Mrak, P | 1 |
| Toplak, H | 1 |
| Kraigher-Krainer, E | 1 |
| März, W | 1 |
| Pilz, S | 1 |
| Onishi, A | 1 |
| Muto, S | 1 |
| Homma, S | 1 |
| Inaba, T | 1 |
| Shuto, R | 1 |
| Kusano, E | 1 |
| Asano, Y | 1 |
| ISASA, FA | 1 |
| ROYER, P | 1 |
| DELAITRE, R | 1 |
| MATHIEU, H | 1 |
| GABILAN, JC | 1 |
| RAYNAUD, C | 1 |
| PASQUALINI, JR | 1 |
| DEBRIS, P | 1 |
| GERBEAUX, S | 1 |
| HABIB, R | 1 |
| Hoff, F | 1 |
| Crane, MG | 1 |
| Harris, JJ | 1 |
| Johns, VJ | 1 |
1 review available for spironolactone and Hypocalcemia
| Article | Year |
|---|---|
Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease.
Topics: Adrenalectomy; Aldosterone; Animals; Bone Density; Bone Diseases; Calcium; Cardiovascular Diseases; | 2014 |
5 other studies available for spironolactone and Hypocalcemia
| Article | Year |
|---|---|
Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemia.
Topics: Aged; Biomarkers; Glycyrrhizic Acid; Humans; Hydrocortisone; Hypocalcemia; Hypophosphatemia; Liddle | 2010 |
[DIAGNOSTIC AND THERAPEUTIC MANAGEMENT OF THE NEPHROTIC SYNDROMES OF INFANCY].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Blood Protein Disorders | 1963 |
[CHRONIC IDIOPATHIC HYPOKALEMIA WITH HYPERKALIURIA IN CHILDREN].
Topics: Adrenal Glands; Aldosterone; Blood Platelet Disorders; Blood Platelets; Child; Corticosterone; Dwarf | 1964 |
[Instinctive food selection as a disease-regulating factor].
Topics: Appetite; Autonomic Nervous System; Disease; Female; Food; Humans; Hunger; Hyperaldosteronism; Hypoc | 1966 |
Hyporeninemic hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Blood Urea Nitrogen; Catecholamines; Diet, Sod | 1972 |