spironolactone has been researched along with Hypertrichosis in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone was started at an oral dose of 25 and increased to 100 mg x m(-2) x day(-1) twice daily for 1 year." | 6.68 | Spironolactone therapy in hypertrichosis. ( Balaban, S; Bas, F; Bundak, R; Darendeliler, F; Demirkol, D; Gunoz, H; Saka, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CAVELL, B | 1 |
| HOEKFELT, B | 1 |
| Darendeliler, F | 1 |
| Bas, F | 1 |
| Balaban, S | 1 |
| Bundak, R | 1 |
| Demirkol, D | 1 |
| Saka, N | 1 |
| Gunoz, H | 1 |
1 trial available for spironolactone and Hypertrichosis
| Article | Year |
|---|---|
Spironolactone therapy in hypertrichosis.
Topics: Administration, Oral; Androgen Antagonists; Child; Female; Hair; Humans; Hypertrichosis; Spironolact | 1996 |
1 other study available for spironolactone and Hypertrichosis
| Article | Year |
|---|---|
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL ADENOMA IN A THREE-YEAR-OLD CHILD.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Adenoma; | 1964 |