spironolactone has been researched along with Hyperthyroidism in 8 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hyperthyroidism: Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0." | 7.96 | The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020) |
| "Adult Wistar rats were randomly distributed into 4 groups; controls, spironolactone treated rats (Spir, 50mg/kg/day), hyperthyroid rats (Hyper, daily intraperitoneal levothyroxine 0." | 3.96 | The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats. ( Aljohmani, AI; Alzoubi, KH; Mayyas, FA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Mayyas, FA | 1 |
| Aljohmani, AI | 1 |
| Alzoubi, KH | 1 |
| OSUGA, T | 1 |
| USHIO, K | 1 |
| Molinatti, GM | 1 |
| Biffignandi, P | 1 |
| Massucchetti, C | 1 |
| Schreiber, V | 1 |
| Stĕpan, J | 1 |
| Kölbel, F | 1 |
| Pribyl, T | 1 |
| Jahodová, J | 1 |
| Kubová, V | 1 |
| Kijima, Y | 1 |
| Sasaoka, T | 1 |
| Antropova, NV | 1 |
| Ivanova, NA | 1 |
| Vinogradova, LA | 1 |
| Bauer, HJ | 1 |
| Pereira, VG | 1 |
| Wajchenberg, BL | 1 |
| Quintão, ER | 1 |
1 review available for spironolactone and Hyperthyroidism
| Article | Year |
|---|---|
[Intracellular and extracellular proteins binding androgenic hormones. Biochemical properties and clinical significance].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androgen-Binding Protein; Androgen-Insensitivity Syndrom | 1983 |
1 trial available for spironolactone and Hyperthyroidism
| Article | Year |
|---|---|
[Search for ways to correct volemic disorders in thyrotoxicosis before surgery].
Topics: Aldosterone; Blood Volume; Circadian Rhythm; Clinical Trials as Topic; Drug Evaluation; Humans; Hype | 1977 |
6 other studies available for spironolactone and Hyperthyroidism
| Article | Year |
|---|---|
The Impact of Spironolactone on Markers of Myocardial Oxidative Status, Inflammation and Remodeling in Hyperthyroid Rats.
Topics: Aldosterone; Animals; Antioxidants; Biomarkers; Blood Pressure; Body Weight; Cardiovascular Diseases | 2020 |
[HYPERKALEMIC THYROTOXIC PERIODIC PARALYSIS REPORT OF AN UNUSUAL CASE].
Topics: Antithyroid Agents; Chlorides; Humans; Hyperkalemia; Hyperthyroidism; Paralyses, Familial Periodic; | 1963 |
Failure of the aldosterone antagonist spironolactone to inhibit myocardial hypertrophy produced by experimental hyperthyroidism and accompanied by "apparent" digoxin immunoreactivity in the blood.
Topics: Animals; Antigen-Antibody Reactions; Cardiomegaly; Digoxin; Heart; Hyperthyroidism; Male; Organ Size | 1980 |
[Hypokalemic paralysis in a case with hyperthyroidism and idiopathic hyperaldosteronism].
Topics: Female; Humans; Hyperaldosteronism; Hyperthyroidism; Hypokalemia; Middle Aged; Paralysis; Periodicit | 1983 |
[Periodic paralyses].
Topics: Adrenal Insufficiency; Adult; Humans; Hyperaldosteronism; Hyperthyroidism; Hypokalemia; Male; Muscle | 1967 |
Periodic paralysis associated with hyperthyroidism. Study of the precipitating factors.
Topics: Adult; Aldosterone; Familial Mediterranean Fever; Glucose Tolerance Test; Humans; Hyperthyroidism; I | 1968 |