spironolactone has been researched along with Hyperparathyroidism in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 38-year-old woman with hypercalcemia, severe hypertension, and high renin levels was treated with the angiotensin-converting enzyme inhibitor captopril." | 7.66 | Hypertension in a patient with hypercalcemia: captopril and verapamil. ( Brunner, HR; Burckhardt, P; Gavras, H; Waeber, B, 1982) |
| " First, we performed a post-hoc analysis of the effect of eplerenone on parathyroid hormone levels in primary hyperparathyroidism (EPATH) study, a randomized controlled trial (RCT) in 110 patients with primary hyperparathyroidism (pHPT)." | 5.27 | Mineralocorticoid Receptor Blockers and Aldosterone to Renin Ratio: A Randomized Controlled Trial and Observational Data. ( Aberer, F; Alesutan, I; Bachmann, A; Catena, C; Grübler, MR; März, W; Meinitzer, A; Obermayer-Pietsch, B; Pandis, M; Pilz, S; Schwetz, V; Sechi, LA; Tomaschitz, A; Trummer, C; Verheyen, N; Voelkl, J, 2018) |
| " The recent introduction of a novel, long-acting testosterone formulation (testosterone undecanoate) which only requires one intramuscular injection every 3 months, together with the already available hydroalcoholic testosterone gels, appear to be promising alternatives to the previous standard substitution therapy for male hypogonadism." | 4.83 | [The latest developments in endocrinology 2004/2005]. ( Fottner, C; Weber, MM, 2006) |
| "A 38-year-old woman with hypercalcemia, severe hypertension, and high renin levels was treated with the angiotensin-converting enzyme inhibitor captopril." | 3.66 | Hypertension in a patient with hypercalcemia: captopril and verapamil. ( Brunner, HR; Burckhardt, P; Gavras, H; Waeber, B, 1982) |
| "Hyperparathyroidism and hyperaldosteronism coexisted in association with medullary sponge kidneys in a 27-year-old woman with severe hypertension." | 1.26 | Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension. ( Hellman, DE; Kartchner, M; Komar, N; Mayes, D; Pitt, M, 1980) |
| "In an 18-year-old boy with Bartter's syndrome, hypophosphatemia was discovered (2." | 1.26 | Hypophosphatemia and hyperparathyroidism in a case of Bartter's syndrome. ( Bernheim, J; David, L; François, R; Sann, L, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilz, S | 1 |
| Trummer, C | 1 |
| Verheyen, N | 1 |
| Schwetz, V | 1 |
| Pandis, M | 1 |
| Aberer, F | 1 |
| Grübler, MR | 1 |
| Meinitzer, A | 1 |
| Bachmann, A | 1 |
| Voelkl, J | 1 |
| Alesutan, I | 1 |
| Catena, C | 1 |
| Sechi, LA | 1 |
| März, W | 1 |
| Obermayer-Pietsch, B | 1 |
| Tomaschitz, A | 1 |
| LAMBERG, BA | 1 |
| TORSTI, P | 1 |
| Chhokar, VS | 1 |
| Sun, Y | 1 |
| Bhattacharya, SK | 1 |
| Ahokas, RA | 1 |
| Myers, LK | 1 |
| Xing, Z | 1 |
| Smith, RA | 1 |
| Gerling, IC | 1 |
| Weber, KT | 1 |
| Fottner, C | 1 |
| Weber, MM | 1 |
| Waeber, B | 1 |
| Brunner, HR | 1 |
| Burckhardt, P | 1 |
| Gavras, H | 1 |
| Hellman, DE | 1 |
| Kartchner, M | 1 |
| Komar, N | 1 |
| Mayes, D | 1 |
| Pitt, M | 1 |
| Sann, L | 1 |
| David, L | 1 |
| Bernheim, J | 1 |
| François, R | 1 |
1 review available for spironolactone and Hyperparathyroidism
| Article | Year |
|---|---|
[The latest developments in endocrinology 2004/2005].
Topics: Adrenal Gland Neoplasms; Adult; Bone Density Conservation Agents; Chronic Kidney Disease-Mineral and | 2006 |
1 trial available for spironolactone and Hyperparathyroidism
| Article | Year |
|---|---|
Mineralocorticoid Receptor Blockers and Aldosterone to Renin Ratio: A Randomized Controlled Trial and Observational Data.
Topics: Aged; Aldosterone; Double-Blind Method; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperparathy | 2018 |
5 other studies available for spironolactone and Hyperparathyroidism
| Article | Year |
|---|---|
THE DEPENDENCE OF CALCIUM EXCRETION ON ADRENAL STEROIDS. STUDIES WITH CHLOROTHIAZIDE IN PATIENTS WITH IMPAIRED ADRENAL FUNCTION.
Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenalectomy; Blo | 1964 |
Hyperparathyroidism and the calcium paradox of aldosteronism.
Topics: Aldosterone; Animals; Bone Density; Bone Resorption; Calcium; Hyperaldosteronism; Hyperparathyroidis | 2005 |
Hypertension in a patient with hypercalcemia: captopril and verapamil.
Topics: Adult; Captopril; Drug Therapy, Combination; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hyp | 1982 |
Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension.
Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperparathyroidism | 1980 |
Hypophosphatemia and hyperparathyroidism in a case of Bartter's syndrome.
Topics: Adolescent; Alkalosis; Bartter Syndrome; Humans; Hyperaldosteronism; Hyperparathyroidism; Hypokalemi | 1978 |