spironolactone has been researched along with Hyperlipemia in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperlipidemia is prevalent in hypertension, but the cause of this association is unknown." | 1.28 | Hyperlipidemia in hypertension: causes and prevention. ( Ames, RP, 1991) |
| "Clofibrate was effective in all animal models, but the spirolactone 4 exhibited antitriglyceridemic activity only in the Triton model." | 1.26 | Synthesis and pharmacological evaluation of a clofibrate-related tricyclic spirolactone, 5-chloro-4',5-dihydrospiro[benzofuran-2(3H),3'(2'H)-furan]-2'-one. ( Baldwin, JR; Cavestri, RC; Feller, DR; Newman, HA; Sober, CL; Witiak, DT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramírez, E | 1 |
| Klett-Mingo, M | 1 |
| Ares-Carrasco, S | 1 |
| Picatoste, B | 1 |
| Ferrarini, A | 1 |
| Rupérez, FJ | 1 |
| Caro-Vadillo, A | 1 |
| Barbas, C | 1 |
| Egido, J | 1 |
| Tuñón, J | 1 |
| Lorenzo, Ó | 1 |
| Gkizas, SI | 1 |
| Apostolakis, E | 1 |
| Pagoulatou, E | 1 |
| Mavrilas, D | 1 |
| Papachristou, DJ | 1 |
| Koletsis, E | 1 |
| Papalois, A | 1 |
| Papadaki, H | 1 |
| Alexopoulos, D | 1 |
| ROYER, P | 1 |
| DELAITRE, R | 1 |
| MATHIEU, H | 1 |
| GABILAN, JC | 1 |
| RAYNAUD, C | 1 |
| PASQUALINI, JR | 1 |
| DEBRIS, P | 1 |
| GERBEAUX, S | 1 |
| HABIB, R | 1 |
| Fleischman, A | 1 |
| Mansfield, J | 1 |
| Marone, C | 1 |
| Beretta-Piccoli, C | 1 |
| Weidmann, P | 1 |
| Witiak, DT | 1 |
| Cavestri, RC | 1 |
| Newman, HA | 1 |
| Baldwin, JR | 1 |
| Sober, CL | 1 |
| Feller, DR | 1 |
| Ames, RP | 1 |
7 other studies available for spironolactone and Hyperlipemia
| Article | Year |
|---|---|
Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes.
Topics: Animals; Apoptosis; Cardiomegaly; Cell Line; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; D | 2013 |
Aldosterone receptor inhibition alters the viscoelastic biomechanical behavior of the aortic wall.
Topics: Aldosterone; Animals; Aorta; Biomechanical Phenomena; Blood Pressure; Disease Progression; Elasticit | 2010 |
[CHRONIC IDIOPATHIC HYPOKALEMIA WITH HYPERKALIURIA IN CHILDREN].
Topics: Adrenal Glands; Aldosterone; Blood Platelet Disorders; Blood Platelets; Child; Corticosterone; Dwarf | 1964 |
Diagnosis and treatment of polycystic ovarian syndrome and insulin resistance.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Hyperandrogenism; Hyperlipidemia | 2005 |
[Basis and clinical aspects of diuretic drug therapy].
Topics: Acetazolamide; Benzothiadiazines; Diuretics; Edema; Edema, Cardiac; Furosemide; Glaucoma; Humans; Hy | 1979 |
Synthesis and pharmacological evaluation of a clofibrate-related tricyclic spirolactone, 5-chloro-4',5-dihydrospiro[benzofuran-2(3H),3'(2'H)-furan]-2'-one.
Topics: Animals; Clofibrate; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Polyethylene Glycols; Rats; | 1978 |
Hyperlipidemia in hypertension: causes and prevention.
Topics: Benzothiadiazines; Blood Glucose; Blood Pressure; Diuretics; Drug Therapy, Combination; Humans; Hype | 1991 |