spironolactone has been researched along with Hyperaldosteronism in 608 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hyperaldosteronism: A condition caused by the overproduction of ALDOSTERONE. It is characterized by sodium retention and potassium excretion with resultant HYPERTENSION and HYPOKALEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antihypertensive effect of spironolactone was significantly greater than that of eplerenone in hypertension associated with primary aldosteronism." | 9.15 | A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism. ( Connell, JM; MacDonald, TM; McInnes, GT; Ménard, J; Parthasarathy, HK; Ruilope, LM; White, WB; Williams, B; Williams, GH; Young, WF, 2011) |
| "The aim of this prospective, randomised, open-label, blinded-end point study was to compare the efficacy and safety of eplerenone versus spironolactone in patients with bilateral idiopathic hyperaldosteronism (IHA)." | 9.13 | Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. ( Anagnostis, P; Athyros, VG; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Pagourelias, ED; Papageorgiou, A; Tziomalos, K, 2008) |
| "The study was undertaken to determine the possible effect of an aldosterone antagonist, spironolactone (SP), on red blood cell sodium-hydrogen exchange (NHE) enhancement in primary aldosteronism (PA) and essential hypertension (EH)." | 9.08 | Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism. ( Koldanov, R; Koren, W; Postnov, IY; Postnov, YV, 1997) |
| "The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy." | 7.78 | Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012) |
| " We are not aware of any published QOL assessment in patients with bilateral primary aldosteronism (BPA), before or after commencing medical treatment (MT) with spironolactone and/or amiloride." | 7.77 | Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically. ( Ahmed, AH; Gordon, RD; Pimenta, E; Stowasser, M; Sukor, N, 2011) |
| "We report the case of normoaldosterone spironolactone sensitive hypertension." | 7.73 | [Normoaldosterone spironolactone sensitive hypertension--a case report]. ( Herman, ZS; Krysiak, R; Okopień, B, 2005) |
| "We report the case of normoaldosterone spironolactone sensitive hypertension." | 7.73 | [Normoaldosterone spironolactone sensitive hypertension]. ( Herman, ZS; Krysiak, R; Okopień, B, 2006) |
| "The aim of our study was to compare serum leptin levels in patients with primary hyperaldosteronism (PA) with those of healthy subjects and to explore the relationship of serum leptin levels and the parameters of insulin action in these patients before and after surgical or pharmacological treatment." | 7.71 | Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: relationships to insulin sensitivity. ( Haluzík, M; Prázný, M; Sindelka, G; Skrha, J; Widimský, J; Zelinka, T, 2002) |
| "We evaluated the effects of prolonged spironolactone treatment on aldosterone secretion in patients with primary aldosteronism." | 7.69 | Aldosterone response to adrenocorticotrophin and furosemide in primary aldosteronism after prolonged spironolactone treatment. ( Ichikawa, S; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sakamoto, H; Sato, K; Yagi, A, 1994) |
| "A case of primary aldosteronism is presented in which the CT scan was initially misleading, adrenocortical scintigraphy was rendered inaccurate by pharmacological interference of spironolactone, and selective adrenal venous sampling of aldosterone was technically difficult." | 7.69 | Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism. ( Freitas, JE; Grekin, R; Gross, MD; Shapiro, B, 1994) |
| "A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years." | 7.68 | Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992) |
| "Time-related changes in plasma levels of aldosterone, deoxycorticosterone, corticosterone, and cortisol were studied during treatment with spironolactone in 8 patients with primary aldosteronism due to adenomas." | 7.68 | Time-related changes in plasma adrenal steroids during treatment with spironolactone in primary aldosteronism. ( Ichikawa, S; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sakamoto, H; Takayama, Y, 1990) |
| "Aldosterone-producing adenomas in patients who have not been given spironolactone are more responsive to ACTH than to angiotensin II." | 7.67 | In vitro responses of aldosterone-producing adenomas to angiotensin II and ACTH after treatment with spironolactone before adrenalectomy. ( Wisgerhof, M, 1984) |
| "So-called Spironolactone bodies are reported in four adrenal cortical adenomas that were removed from patients with primary hyperaldosteronism, treated preoperatively with spironolactone." | 7.66 | [Spironolactone bodies. Light and electron microscope study apropos of 4 cases of adrenal adenomas with primary hyperaldosteronism]. ( Abelanet, R; Daudet-Monsac, M; Lellouch-Tubiana, A; Louvel, A; Vacher-Lavenu, MC, 1982) |
| "Spironolactone alone in full dosage failed to correct hypertension in a patient with Conn's syndrome and renal impairment, although the previously increased total exchangeable sodium fell to normal and the previously suppressed plasma angiotensin II did not rise above the normal range." | 7.66 | Combined captopril and spironolactone treatment in Conn's syndrome with renal impairment and refractory hypertension. ( Atkinson, AB; Brown, JJ; Davies, DL; Lever, AF; Robertson, JI, 1981) |
| "Plasma 18-hydroxycorticosterone (180HB) concentration was measured in 23 patients with primary aldosteronism." | 7.66 | The significance of elevated levels of plasma 18-hydroxycorticosterone in patients with primary aldosteronism. ( Biglieri, EG; Schambelan, M, 1979) |
| "Serum and muscle electrolytes were determined in a case of primary aldosteronism before and after potassium and magnesium infusions as well as spironolactone treatment and following surgery." | 7.66 | Effects on muscle electrolytes of potassium and magnesium infusions, spironolactone medication and operation in a case of primary aldosteronism. ( Dyckner, T; Wester, PO, 1979) |
| "To determine the effect of aldosterone antagonist on renal prostaglandin E synthesis, the rate of urinary excretion of immunoreactive prostaglandin E was measured radioimmunologically before and during the oral administration of an aldosterone antagonist, spironolactone, in 5 patients with essential hypertension, 3 with primary aldosteronism and 2 with postoperative primary aldosteronism." | 7.66 | Effect of spironolactone on urinary excretion of immunoreactive prostaglandin E in essential hypertension and primary aldosteronism. ( Abe, K; Chiba, S; Irokawa, N; Otsuka, Y; Sakurai, Y; Sato, M; Seino, M; Yasujima, M; Yoshinaga, K, 1978) |
| " The short-term (9 days) effect of indomethacin in combination with spironolactone was a suppression of hyperreninemia and hyperaldosteronism and an increase in vascular sensitivity to angiotensin II associated with potassium and sodium retention." | 7.66 | Bartter's syndrome without hyperplasia of the juxtaglomerular apparatus, treated with indomethacin. ( Kornerup, HJ; Pedersen, EB; Petersen, VP, 1978) |
| "Spironolactone bodies were observed in an adrenal cortical adenoma that was removed from a patient with primary hyperaldosteronism (Conn syndrome) treated preoperatively with spironolactone." | 7.65 | Spironolactone bodies in an adrenal adenoma. ( Cooper, PH; Shrago, SS; Waisman, J, 1975) |
| "Urinary kallikrein excretion was measured before and after administration of spironolactone in 12 patients with essential hypertension (including 7 patients with low renin and 5 patients with normal renin) and 6 patients with primary aldosteronism." | 7.65 | Effect of spironolactone on urinary kallikrein excretion in patients with essential hypertension and in primary aldosteronism. ( Abe, K; Chiba, S; Irokawa, N; Otsuka, Y; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977) |
| "During treatment with indomethacin in a patient with Bartter's syndrome, hypokalemia, high plasma renin concentration, hyperaldosteronism and decreased sensitivity to angiotensin infusion were corrected." | 7.65 | Bartter's syndrome with hyperplasia of renomedullary cells: successful treatment with indomethacin. ( Amery, A; Clement, J; Michielsen, P; van Damme B, B; Verberckmoes, R, 1976) |
| "The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 7.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
| "Primary aldosteronism (PA) represents the most common cause of secondary hypertension." | 6.80 | Long-term effects of adrenalectomy or spironolactone on blood pressure control and regression of left ventricle hypertrophy in patients with primary aldosteronism. ( Holaj, R; Indra, T; Petrák, O; Rosa, J; Šomlóová, Z; Štrauch, B; Widimský, J, 2015) |
| "Primary aldosteronism (PA) has deleterious effects on kidney function independent of blood pressure levels." | 6.78 | Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism. ( Allolio, B; Beuschlein, F; Diederich, S; Endres, S; Fischer, E; Fourkiotis, V; Lang, K; Quinkler, M; Reincke, M; Rump, LC; Vonend, O; Willenberg, HS, 2013) |
| "Ventricular arrhythmia was recognized as the most common cause of death in this population." | 6.69 | Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. ( Coelho, O; Gruppi, CJ; Mady, C; Mansur, A; Maranhão, M; Ramires, FJ; Ramires, JA, 2000) |
| "A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention." | 6.48 | Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012) |
| "Aldosterone was in the past considered only as a prohypertensinogenic agent." | 6.46 | Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010) |
| "Patients with primary aldosteronism (PA) have a high prevalence of microalbuminuria (MAU), which leads to more severe systemic vascular damage." | 5.62 | Long-term impact of spironolactone compliance on microalbuminuria in patients with primary aldosteronism. ( Hu, J; Li, N; Luo, Q; Wang, G; Wang, M; Wang, X; Zhang, D; Zhang, W, 2021) |
| "Primary aldosteronism (PA) is the most frequent form of endocrine hypertension." | 5.56 | Spironolactone reduces biochemical markers of bone turnover in postmenopausal women with primary aldosteronism. ( Adolf, C; Bidlingmaier, M; Braun, LT; Fuss, CT; Hahner, S; Handgriff, L; Heinrich, DA; Künzel, H; Reincke, M; Schneider, H; Sturm, L, 2020) |
| "Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status." | 5.43 | Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016) |
| "Treatment with spironolactone inhibited Akt/AS160 phosphorylation, reduced Rab-dependent Kv1." | 5.43 | Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice. ( Buschmeyer, B; Koehncke, C; Lisewski, U; Pieske, B; Roepke, TK; Wilck, N, 2016) |
| "Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity." | 5.43 | The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016) |
| "The incidence of left ventricular hypertrophy (LVH) in primary aldosteronism (PA) is higher than in essential hypertension." | 5.39 | Regression of left ventricular hypertrophy in patients with primary aldosteronism/low-renin hypertension on low-dose spironolactone. ( Bergman, M; Chagnac, A; Gafter, U; Herman-Edelstein, M; Korzets, A; Ori, Y; Salman, H; Zingerman, B, 2013) |
| "Primary aldosteronism (PA) is mainly caused by aldosterone-producing adenoma and idiopathic bilateral adrenal hyperplasia (IHA)." | 5.38 | Spontaneous remission of idiopathic aldosteronism after long-term treatment with spironolactone: results from the German Conn's Registry. ( Beuschlein, F; Bidlingmaier, M; Degenhart, C; Fischer, E; Jung, P; Reincke, M, 2012) |
| "Thus, in rats with aldosteronism, in which a reduction in effective refractory period was not evident, the mechanism for VA susceptibility is presumably linked to a decrease in conduction velocity and/or increased dispersion of refractoriness, probably caused by consequential myocardial fibrosis." | 5.37 | Spironolactone prevents the inducibility of ventricular tachyarrhythmia in rats with aldosteronism. ( Bellary, SR; de Jongh Curry, AL; Deshmukh, PA; Kamalov, G; Magotra, M; Schwender, FT; Sun, Y; Weber, KT, 2011) |
| "Resistant hypertension has evolved as an important global health care problem." | 5.37 | What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011) |
| "No reports have described mycotic pseudoaneurysm in the aortic arch in a diabetic patient associated with primary aldosteronism." | 5.36 | Successful treatment of a mycotic aortic pseudoaneurysm in a patient with type 2 diabetes mellitus while treating primary aldosteronism with spironolactone. ( Fukata, M; Furukawa, H; Ito, H; Ito, Y; Konishi, T; Matsuzawa, Y; Nishikawa, T; Okura, K; Saito, J; Yoshimura, K, 2010) |
| " A maximal possible effect (E(max)) model was employed to determine the basic pharmacodynamic parameters of spironolactone, measured by high-performance liquid chromatography, in antagonizing the renal effects of aldosterone." | 5.36 | A preclinical pharmacokinetic and pharmacodynamic approach to determine a dose of spironolactone for treatment of congestive heart failure in dog. ( Elliott, J; Guyonnet, J; Kaltsatos, V, 2010) |
| "Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease." | 5.35 | Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009) |
| "We report a rare case of adrenocortical carcinoma." | 5.32 | Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. ( Azizlerli, H; Kapran, Y; Kurtulmus, N; Yarman, S, 2004) |
| "Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension." | 5.29 | Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993) |
| " First, we performed a post-hoc analysis of the effect of eplerenone on parathyroid hormone levels in primary hyperparathyroidism (EPATH) study, a randomized controlled trial (RCT) in 110 patients with primary hyperparathyroidism (pHPT)." | 5.27 | Mineralocorticoid Receptor Blockers and Aldosterone to Renin Ratio: A Randomized Controlled Trial and Observational Data. ( Aberer, F; Alesutan, I; Bachmann, A; Catena, C; Grübler, MR; März, W; Meinitzer, A; Obermayer-Pietsch, B; Pandis, M; Pilz, S; Schwetz, V; Sechi, LA; Tomaschitz, A; Trummer, C; Verheyen, N; Voelkl, J, 2018) |
| "Spironolactone treatment normalized the arterial pressure in patients with primary aldosteronism at all Na intakes." | 5.27 | Effect of spironolactone on fluid volumes and adrenal steroids in primary aldosteronism. ( Hirano, Y; Ichikawa, S; Kogure, M; Matsuo, H; Murata, K; Sakamaki, T; Tajima, Y; Yagi, S, 1984) |
| "In untreated patients with primary aldosteronism caused either by adrenal adenoma or hyperplasia plasma aldosterone and cortisol concentrations fluctuated in unison and dexamethasone reduced both hormones markedly." | 5.26 | Primary aldosteronism: effects of inhibition of ACTH and potassium administration on plasma aldosterone concentration. ( Ganguly, A; Luetscher, JA; Weinberger, MH, 1982) |
| "In primary aldosteronism the type of adrenal lesion was correctly identified in 28 of 40 patients (70%) by standard adrenal scintigraphy." | 5.26 | Adrenal scintigraphy in primary aldosteronism. Spironolactone as a cause of incorrect classification between adenoma and hyperplasia. ( Fischer, M; Vetter, H; Vetter, W; Winterg, B; Zidek, W, 1982) |
| " We conclude that aldosterone antagonists in the dosage used had no effect on the course of postoperative hyperaldosteronism." | 5.26 | Hyperaldosteronism after heart surgery in children. Part I: Treatment with aldosterone antagonists. ( Haschke, F; Parth, K; Wimmer, M, 1981) |
| "Twenty patients suffering from primary hyperaldosteronism were studied." | 5.26 | [The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977) |
| "The antihypertensive effect of spironolactone was significantly greater than that of eplerenone in hypertension associated with primary aldosteronism." | 5.15 | A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism. ( Connell, JM; MacDonald, TM; McInnes, GT; Ménard, J; Parthasarathy, HK; Ruilope, LM; White, WB; Williams, B; Williams, GH; Young, WF, 2011) |
| "The aim of this prospective, randomised, open-label, blinded-end point study was to compare the efficacy and safety of eplerenone versus spironolactone in patients with bilateral idiopathic hyperaldosteronism (IHA)." | 5.13 | Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. ( Anagnostis, P; Athyros, VG; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Pagourelias, ED; Papageorgiou, A; Tziomalos, K, 2008) |
| "The study was undertaken to determine the possible effect of an aldosterone antagonist, spironolactone (SP), on red blood cell sodium-hydrogen exchange (NHE) enhancement in primary aldosteronism (PA) and essential hypertension (EH)." | 5.08 | Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism. ( Koldanov, R; Koren, W; Postnov, IY; Postnov, YV, 1997) |
| "The first mineralocorticoid receptor (MR) antagonist, spironolactone, was developed almost 60 years ago to treat primary aldosteronism and pathological edema." | 4.93 | Third-generation Mineralocorticoid Receptor Antagonists: Why Do We Need a Fourth? ( Gomez-Sanchez, EP, 2016) |
| " Hyperaldosteronism due to klotho deficiency results in vascular calcification, which can be mitigated by spironolactone treatment." | 4.90 | Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease. ( Fahrleitner-Pammer, A; Gaksch, M; Grübler, M; Kienreich, K; Kraigher-Krainer, E; März, W; Mrak, P; Pieske, B; Pilz, S; Ritz, E; Rus-Machan, J; Tomaschitz, A; Toplak, H; Verheyen, N, 2014) |
| " Thereafter, spironolactone treatment successfully ameliorated hyperaldosteronism for 7 years with no discernible adrenal enlargement." | 4.90 | Discordant genotype-phenotype correlation in familial hyperaldosteronism type III with KCNJ5 gene mutation: a patient report and review of the literature. ( Adachi, M; Asakura, Y; Hasegawa, T; Homma, K; Muroya, K; Sugiyama, K, 2014) |
| " The recent introduction of a novel, long-acting testosterone formulation (testosterone undecanoate) which only requires one intramuscular injection every 3 months, together with the already available hydroalcoholic testosterone gels, appear to be promising alternatives to the previous standard substitution therapy for male hypogonadism." | 4.83 | [The latest developments in endocrinology 2004/2005]. ( Fottner, C; Weber, MM, 2006) |
| " The 30% improvement in mortality (and 35% in morbidity) seen in the RALES trial with the addition of low-dose spironolactone to best practice therapy in moderate to severe heart failure, similarly points to an unrecognized role for aldosterone in the pathophysiology of heart failure." | 4.81 | Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system. ( Funder, JW; Young, MJ, 2002) |
| "Until recently, spironolactone was considered only as an antagonist at the aldosterone receptors of the epithelial cells of the kidney and was used clinically in the treatment of hyperaldosteronism and, occasionally, as a K(+)-sparing diuretic." | 4.81 | The spironolactone renaissance. ( Brown, L; Doggrell, SA, 2001) |
| "Spironolactone treatment might increase insulin resistance in patients with PA." | 3.96 | Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism. ( Chang, CH; Chung, SD; Hu, YH; Lin, YF; Peng, KY; Wu, VC, 2020) |
| "Longstanding primary aldosteronism (PA) has deleterious effects on renal function, often masked until treatment (adrenalectomy or spironolactone) is initiated." | 3.85 | Effects of Treating Primary Aldosteronism on Renal Function. ( Deinum, J; Kramers, BJ; Kramers, C; Lenders, JW, 2017) |
| "Spironolactone, which is a potent mineralocorticoid receptor antagonist, represents the first line medical treatment of primary aldosteronism (PA)." | 3.83 | SFE/SFHTA/AFCE consensus on primary aldosteronism, part 7: Medical treatment of primary aldosteronism. ( Herpin, D; Lefebvre, H; Pechère-Bertschi, A, 2016) |
| "Forty-two patients with confirmed primary aldosteronism (21 with aldosterone-producing adenoma treated by unilateral laparoscopic adrenalectomy, 21 treated with spironolactone) were investigated by carotid ultrasound at baseline and 1 and 6 years after the specific treatment." | 3.81 | Long-term effect of specific treatment of primary aldosteronism on carotid intima-media thickness. ( Holaj, R; Indra, T; Michalský, D; Novák, K; Petrák, O; Rosa, J; Šomlóová, Z; Štrauch, B; Wichterle, D; Widimský, J; Zelinka, T, 2015) |
| "Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and as a result, can form concentrically laminated electron dense spironolactone body inclusions within the adrenal gland." | 3.80 | Adrenal gland inclusions in patients treated with aldosterone antagonists (Spironolactone/Eplerenone): incidence, morphology, and ultrastructural findings. ( Calomeni, EP; Nadasdy, T; Patel, KA; Zynger, DL, 2014) |
| " Patients with IIH should be evaluated for aldosteronism and considered for spironolactone therapy." | 3.79 | Idiopathic intracranial hypertension associated with either primary or secondary aldosteronism. ( Khalid, H; Khan, MU; Salpietro, V; Weber, KT, 2013) |
| "The aim of this paper is to report a case of unilateral PA with spontaneous remission and reduction of cardiac hypertrophy after long-term spironolactone (SP) therapy." | 3.78 | Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy. ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012) |
| " We are not aware of any published QOL assessment in patients with bilateral primary aldosteronism (BPA), before or after commencing medical treatment (MT) with spironolactone and/or amiloride." | 3.77 | Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically. ( Ahmed, AH; Gordon, RD; Pimenta, E; Stowasser, M; Sukor, N, 2011) |
| "We conducted a prospective study of patients with primary aldosteronism who were reevaluated 1 yr after either adrenalectomy or treatment with spironolactone." | 3.75 | Intrarenal hemodynamics in primary aldosteronism before and after treatment. ( Bazzocchi, M; Catena, C; Di Fabio, A; Sechi, LA; Uzzau, A, 2009) |
| "3%) patients had primary hyperaldosteronism, and response to spironolactone treatment further confirmed this diagnosis." | 3.74 | Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study. ( Douma, S; Doumas, M; Kartali, N; Papadopoulos, N; Papaefthimiou, P; Petidis, K; Triantafyllou, A; Vogiatzis, K; Zamboulis, C, 2008) |
| "Spironolactone is frequently used before adrenalectomy for hyperaldosteronism to control blood pressure." | 3.74 | Good blood pressure control on antihypertensives, not only response to spironolactone, predicts improved outcome after adrenalectomy for aldosteronoma. ( Brunaud, L; Clark, OH; Duh, QY; Kebebew, E; Lee, J; Lindsay, S; Zarnegar, R, 2007) |
| "We hypothesized that the increased urinary Ca2+ and Mg2+ excretion and bone loss that accompanies aldosteronism is aggravated with furosemide and is attenuated by spironolactone." | 3.73 | Diuretics and bone loss in rats with aldosteronism. ( Bhattacharya, SK; Chhokar, VS; Law, PH; Sun, Y; Weber, KT, 2005) |
| "We hypothesized that aldosteronism is accompanied by hypercalciuria and hypermagnesuria that lead to bone loss, which could be rescued by hydrochlorothiazide and spironolactone." | 3.73 | Bone loss in rats with aldosteronism. ( Bhattacharya, SK; Chhokar, VS; Runyan, AL; Runyan, JW; Sun, Y; Weber, KT, 2005) |
| "We report the case of normoaldosterone spironolactone sensitive hypertension." | 3.73 | [Normoaldosterone spironolactone sensitive hypertension--a case report]. ( Herman, ZS; Krysiak, R; Okopień, B, 2005) |
| "We report the case of normoaldosterone spironolactone sensitive hypertension." | 3.73 | [Normoaldosterone spironolactone sensitive hypertension]. ( Herman, ZS; Krysiak, R; Okopień, B, 2006) |
| "When performed with careful regard to confounding factors, measurement of the aldosterone : renin ratio in all hypertensive individuals, followed by fludrocortisone suppression testing to confirm or exclude primary aldosteronism and adrenal venous sampling to determine the subtype, can result in the detection of significant numbers of patients with specifically treatable or potentially curable hypertension." | 3.72 | High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. ( Archibald, C; Cowley, DC; Gordon, RD; Gunasekera, TG; Smithers, BM; Stowasser, M; Ward, G, 2003) |
| "The aim of our study was to compare serum leptin levels in patients with primary hyperaldosteronism (PA) with those of healthy subjects and to explore the relationship of serum leptin levels and the parameters of insulin action in these patients before and after surgical or pharmacological treatment." | 3.71 | Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: relationships to insulin sensitivity. ( Haluzík, M; Prázný, M; Sindelka, G; Skrha, J; Widimský, J; Zelinka, T, 2002) |
| " Five of these patients with aldosterone producing adenoma were operated on and four patients with idiopathic hyperaldosteronism were treated with spironolactone." | 3.70 | Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment. ( Haas, T; Hilgertová, J; Prázný, M; Sindelka, G; Skrha, J; Widimský, J, 2000) |
| "We evaluated the effects of prolonged spironolactone treatment on aldosterone secretion in patients with primary aldosteronism." | 3.69 | Aldosterone response to adrenocorticotrophin and furosemide in primary aldosteronism after prolonged spironolactone treatment. ( Ichikawa, S; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sakamoto, H; Sato, K; Yagi, A, 1994) |
| "A case of primary aldosteronism is presented in which the CT scan was initially misleading, adrenocortical scintigraphy was rendered inaccurate by pharmacological interference of spironolactone, and selective adrenal venous sampling of aldosterone was technically difficult." | 3.69 | Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism. ( Freitas, JE; Grekin, R; Gross, MD; Shapiro, B, 1994) |
| "A retrospective analysis was performed regarding age and sex of the patients, duration of hypertension, family history of hypertension, preoperative blood pressure, plasma aldosterone concentration (PAC), plasma renin activity (PRA) and efficacy of spironolactone on blood pressure between both groups." | 3.69 | Prognostic factors of primary aldosteronism. ( Chang, CH; Chang, CL; Chang, YY; Ho, HC; Lin, HS; Ou, YC; Wu, HC; Yang, CR, 1996) |
| "The study showed that the main determinants of a surgical cure of hypertension in primary aldosteronism were presence of adenoma and preoperative response to spironolactone." | 3.69 | Factors influencing outcome of surgery for primary aldosteronism. ( Beazley, RM; Celen, O; Melby, JC; O'Brien, MJ, 1996) |
| " Finally, potassium-sparing diuretics, especially spironolactone, play an important role in controlling high blood pressure in patients with primary aldosteronism." | 3.69 | [The clinical spectrum of potassium-sparing diuretics]. ( Greminger, P; Suter, PM, 1997) |
| "A case of primary aldosteronism treated with spironolactone therapy has been followed up for 24 years." | 3.68 | Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma. ( Hashimoto, T; Ito, Y; Koshida, H; Miyamori, I; Morimoto, S; Morise, T; Takeda, R; Yamazaki, T, 1992) |
| "Time-related changes in plasma levels of aldosterone, deoxycorticosterone, corticosterone, and cortisol were studied during treatment with spironolactone in 8 patients with primary aldosteronism due to adenomas." | 3.68 | Time-related changes in plasma adrenal steroids during treatment with spironolactone in primary aldosteronism. ( Ichikawa, S; Murata, K; Nakamura, T; Ono, Z; Sakamaki, T; Sakamoto, H; Takayama, Y, 1990) |
| "Aldosterone-producing adenomas in patients who have not been given spironolactone are more responsive to ACTH than to angiotensin II." | 3.67 | In vitro responses of aldosterone-producing adenomas to angiotensin II and ACTH after treatment with spironolactone before adrenalectomy. ( Wisgerhof, M, 1984) |
| " Hypertension, hypokalaemia, hyperaldosteronism and renin suppression were corrected by unilateral adrenalectomy in 3/5 patients and by spironolactone treatment in 2/5." | 3.67 | Primary aldosteronism is comprised of primary adrenal hyperplasia and adenoma. ( Arteaga, EE; Biglieri, EG; Kater, CE, 1984) |
| "The withdrawal effect of spironolactone treatment on natriuresis was studied in relation to atrial natriuretic peptide (ANP) in five patients with primary aldosteronism due to adenoma." | 3.67 | Role of atrial natriuretic peptide in mineralocorticoid escape phenomenon in patients with primary aldosteronism. ( Ichikawa, S; Kato, T; Kogure, M; Murata, K; Nakamura, T; Sakamaki, T; Sato, K; Tajima, Y, 1987) |
| "The prognosis of hypertension was evaluated pre-operatively in 40 patients with primary aldosteronism owing to adenoma by examining the severity of hypertension, family history of hypertension, age of the patients, duration of hypertension, plasma renin activity, plasma aldosterone concentration, and efficacy of spironolactone (100 mg per day for 10 days) on blood pressure." | 3.67 | Pre-operative evaluation of the prognosis of hypertension in primary aldosteronism owing to adenoma. ( Murai, M; Saito, I; Saruta, T; Suzuki, H; Takita, T; Tazaki, H, 1987) |
| " Serum electrolytes became normal after spironolactone but not after dexamethasone." | 3.66 | Normotensive primary aldosteronism: report of a case. ( Ikeda, F; Imura, H; Kono, T; Oseko, F; Tanimura, H, 1981) |
| " Blood pressure was normal during treatment with spironolactone and during pregnancy, when the action of aldosterone and other similar steroids was presumably blocked by an increased production of progesterone; this suggests that the hypertension is dependent upon sodium-retaining steroids such as aldosterone." | 3.66 | Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism. ( Bartter, FC; Gill, JR, 1981) |
| "So-called Spironolactone bodies are reported in four adrenal cortical adenomas that were removed from patients with primary hyperaldosteronism, treated preoperatively with spironolactone." | 3.66 | [Spironolactone bodies. Light and electron microscope study apropos of 4 cases of adrenal adenomas with primary hyperaldosteronism]. ( Abelanet, R; Daudet-Monsac, M; Lellouch-Tubiana, A; Louvel, A; Vacher-Lavenu, MC, 1982) |
| "Histological sections taken from aldosterone-producing-adenomas and from non-tumorous adrenal cortex of 18 patients treated for primary aldosteronism by unilateral adrenalectomy were examined for spironolactone inclusion bodies." | 3.66 | Factors affecting the frequency of occurrence of spironolactone bodies in aldosteronomas and non-tumorous cortex. ( Cohn, D; Gordon, RD; Jackson, RV, 1983) |
| "Spironolactone alone in full dosage failed to correct hypertension in a patient with Conn's syndrome and renal impairment, although the previously increased total exchangeable sodium fell to normal and the previously suppressed plasma angiotensin II did not rise above the normal range." | 3.66 | Combined captopril and spironolactone treatment in Conn's syndrome with renal impairment and refractory hypertension. ( Atkinson, AB; Brown, JJ; Davies, DL; Lever, AF; Robertson, JI, 1981) |
| " Patients with edema, ascites, or both had significantly greater elevation of plasma aldosterone levels compared to nonedematous patients; these patients also demonstrated a substantial degree of hepatic dysfunction as evidenced by lower serum albumin levels and higher bilirubin and alkaline phosphatase levels." | 3.66 | Hyperaldosteronism associated with liver metastases. ( Citrin, DL; Crowley, J; Pandya, KJ; Whitehead, R, 1980) |
| "Plasma 18-hydroxycorticosterone (180HB) concentration was measured in 23 patients with primary aldosteronism." | 3.66 | The significance of elevated levels of plasma 18-hydroxycorticosterone in patients with primary aldosteronism. ( Biglieri, EG; Schambelan, M, 1979) |
| "Serum and muscle electrolytes were determined in a case of primary aldosteronism before and after potassium and magnesium infusions as well as spironolactone treatment and following surgery." | 3.66 | Effects on muscle electrolytes of potassium and magnesium infusions, spironolactone medication and operation in a case of primary aldosteronism. ( Dyckner, T; Wester, PO, 1979) |
| "In children with congenital heart disease duration and extent of hyperaldosteronism and the influence of spironolactone after surgery with a heart-lung-machine, were evaluated by direct measurement of plasma aldosterone levels." | 3.66 | [The effect of aldosterone antagonists in juvenile heart surgery]. ( Holzer, H; Parth, K; Wimmer, M, 1979) |
| "To determine the effect of aldosterone antagonist on renal prostaglandin E synthesis, the rate of urinary excretion of immunoreactive prostaglandin E was measured radioimmunologically before and during the oral administration of an aldosterone antagonist, spironolactone, in 5 patients with essential hypertension, 3 with primary aldosteronism and 2 with postoperative primary aldosteronism." | 3.66 | Effect of spironolactone on urinary excretion of immunoreactive prostaglandin E in essential hypertension and primary aldosteronism. ( Abe, K; Chiba, S; Irokawa, N; Otsuka, Y; Sakurai, Y; Sato, M; Seino, M; Yasujima, M; Yoshinaga, K, 1978) |
| " The short-term (9 days) effect of indomethacin in combination with spironolactone was a suppression of hyperreninemia and hyperaldosteronism and an increase in vascular sensitivity to angiotensin II associated with potassium and sodium retention." | 3.66 | Bartter's syndrome without hyperplasia of the juxtaglomerular apparatus, treated with indomethacin. ( Kornerup, HJ; Pedersen, EB; Petersen, VP, 1978) |
| "Spironolactone bodies were observed in an adrenal cortical adenoma that was removed from a patient with primary hyperaldosteronism (Conn syndrome) treated preoperatively with spironolactone." | 3.65 | Spironolactone bodies in an adrenal adenoma. ( Cooper, PH; Shrago, SS; Waisman, J, 1975) |
| " Our results show that both before and after a 9-months therapy with spironolactone episodic aldosterone release of an aldosterone producing adrenal adenoma was mediated through ACTH and that endogeneous angiotensin II had no or only little influence." | 3.65 | Control of plasma aldosterone in a patient with Conn's syndrome before and during spironolactone medication. ( Vetter, H; Vetter, W, 1975) |
| "Urinary kallikrein excretion was measured before and after administration of spironolactone in 12 patients with essential hypertension (including 7 patients with low renin and 5 patients with normal renin) and 6 patients with primary aldosteronism." | 3.65 | Effect of spironolactone on urinary kallikrein excretion in patients with essential hypertension and in primary aldosteronism. ( Abe, K; Chiba, S; Irokawa, N; Otsuka, Y; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K, 1977) |
| " Five patients with primary aldosteronism due to adenoma were followed during spironolactone treatment, for 35-55 days after the drug had been stopped, and finally, after surgery." | 3.65 | Volume-pressure relationships during development of mineralocorticoid hypertension in man. ( Derkx, FH; Man in 't Veld, AJ; Schalekamp, DH; Verhoeven, RP; Wenting, GH, 1977) |
| "During treatment with indomethacin in a patient with Bartter's syndrome, hypokalemia, high plasma renin concentration, hyperaldosteronism and decreased sensitivity to angiotensin infusion were corrected." | 3.65 | Bartter's syndrome with hyperplasia of renomedullary cells: successful treatment with indomethacin. ( Amery, A; Clement, J; Michielsen, P; van Damme B, B; Verberckmoes, R, 1976) |
| "Numerous spironolactone bodies have been detected in the zona glomerulosa cells of the adrenal cortex of a 36-year-old spironolactone-treated woman whose non-tumorous right adrenal gland was removed surgically because of primary hyperaldosteronism." | 3.65 | Fine structure and morphogenesis of spironolactone bodies in the zona glomerulosa of the human adrenal cortex. ( Horvath, E; Kovacs, K; Singer, W, 1973) |
| "The effect of prolonged preoperative treatment with spironolactone has been studied in a series of 67 patients with hypertension, aldosterone excess, and low plasma renin." | 3.65 | Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin. ( Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI, 1972) |
| "Primary aldosteronism (PA) is the most common form of secondary hypertension." | 3.01 | Primary aldosteronism in pregnancy. ( Forestiero, V; Monticone, S; Mulatero, P; Sconfienza, E, 2023) |
| "Primary aldosteronism (PA) represents the most common cause of secondary hypertension." | 2.80 | Long-term effects of adrenalectomy or spironolactone on blood pressure control and regression of left ventricle hypertrophy in patients with primary aldosteronism. ( Holaj, R; Indra, T; Petrák, O; Rosa, J; Šomlóová, Z; Štrauch, B; Widimský, J, 2015) |
| "Observational studies in primary hyperaldosteronism suggest a positive relationship between aldosterone and parathyroid hormone (PTH); however, interventions to better characterize the physiological relationship between the renin-angiotensin-aldosterone system (RAAS) and PTH are needed." | 2.79 | Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone. ( Adler, GK; Brown, JM; Garg, R; Garza, AE; Luther, JM; Pojoga, LH; Ruan, DT; Vaidya, A; Williams, GH; Williams, JS, 2014) |
| "Primary aldosteronism (PA) has deleterious effects on kidney function independent of blood pressure levels." | 2.78 | Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism. ( Allolio, B; Beuschlein, F; Diederich, S; Endres, S; Fischer, E; Fourkiotis, V; Lang, K; Quinkler, M; Reincke, M; Rump, LC; Vonend, O; Willenberg, HS, 2013) |
| "Spironolactone treatment (19 patients in the high aldosterone group and 15 patients from the normal aldosterone group participated in the follow-up) resulted in a significant decrease in clinic systolic blood pressure, right and left ventricular end diastolic volumes, left atrial volume, left ventricular mass, and brain natriuretic peptide at 3 and 6 months of follow-up in patients with high aldosterone, whereas in those with normal aldosterone status, spironolactone decreased blood pressure and left ventricular mass without changes in ventricular or atrial volumes or plasma brain natriuretic peptide." | 2.75 | Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study. ( Aban, I; Ahmed, M; Calhoun, DA; Corros, C; Dell'Italia, LJ; Denney, T; Gaddam, K; Gupta, H; Husain, A; Inusah, S; Lloyd, SG; Oparil, S; Pimenta, E, 2010) |
| "The Taiwan Society of Aldosteronism (TSA) Task Force acknowledged the novel issues of PA and reached a group consensus on PA in Taiwan by collecting the best available evidence and conducting one group meeting, several conference calls, and multiple e-mail communications." | 2.72 | Taiwan mini-frontier of primary aldosteronism: Updating treatment and comorbidities detection. ( Chan, CK; Chang, YY; Chen, ZW; Huang, WC; Lin, YH; Tsai, YC; Wu, CY; Wu, KH; Wu, VC; Yen, IW, 2021) |
| "Primary hyperaldosteronism was confirmed if plasma renin activity was <1." | 2.70 | Hyperaldosteronism among black and white subjects with resistant hypertension. ( Calhoun, DA; Nishizaka, MK; Thakkar, RB; Weissmann, P; Zaman, MA, 2002) |
| "Ventricular arrhythmia was recognized as the most common cause of death in this population." | 2.69 | Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. ( Coelho, O; Gruppi, CJ; Mady, C; Mansur, A; Maranhão, M; Ramires, FJ; Ramires, JA, 2000) |
| "Hypertension was associated with a significant increase in stroke volume and a non-significant increase in cardiac index." | 2.68 | [Conn's syndrome. Study of systemic cardiovascular hemodynamics after medical treatment with spironolactone and after surgical treatment]. ( Amah, G; Ben Maiz, H; Blacher, J; Girerd, X; Kheder, A; Safar, M, 1997) |
| "Hyperaldosteronism was confirmed in 74% of 72 consecutive patients admitted for acute myocardial infarction, in 85% if patients previously treated by an antialdosterone drug or admitted after the acute phase are excluded, and in 96% if patients with cardiac failure are included." | 2.65 | [Hyperaldosteronism in the acute phase of myocardial infarction. Effects of its treatment on the prevention of ventricular fibrillation]. ( Denis, B; Dimitriou, R; Machecourt, J; Page, E; Reboud, JP; Wolf, JE, 1984) |
| "Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension." | 2.53 | Diagnosing and Managing Primary Aldosteronism in Hypertensive Patients: a Case-Based Approach. ( Carey, RM, 2016) |
| "Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 2.52 | Progress in primary aldosteronism: mineralocorticoid receptor antagonists and management of primary aldosteronism in pregnancy. ( Reincke, M; Riester, A, 2015) |
| " The range of adverse effects experienced with spironolactone has led to its modification and the consequent synthesis of eplerenone." | 2.52 | Efficacy and safety of mineralocorticoid receptors in mild to moderate arterial hypertension. ( Gaudio, C; Greco, C; Patti, G; Pelliccia, F; Rosano, G; Volterrani, M, 2015) |
| "Primary aldosteronism (PA) is the most common cause of secondary hypertension." | 2.52 | Systematic review of surgery and outcomes in patients with primary aldosteronism. ( Johannsson, G; Muth, A; Ragnarsson, O; Wängberg, B, 2015) |
| "Hypertension is one of the most common cardiovascular diseases during pregnancy." | 2.52 | [Hypertension in the course of primary aldosteronism during pregnancy]. ( Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M, 2015) |
| "Primary aldosteronism, caused by autonomous secretion of aldosterone by the adrenals, is estimated to account for at least 5% of hypertension cases." | 2.52 | Pharmacological treatment of aldosterone excess. ( Deinum, J; Lenders, JW; Riksen, NP, 2015) |
| "The identification of primary aldosteronism as a common cause of resistant hypertension is a significant advance in our ability to care for patients with hypertension." | 2.49 | Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism. ( Weiner, ID, 2013) |
| "A close association exists between hyperaldosteronism, RHTN, and obstructive sleep apnea (OSA) based upon recent studies which indicate that OSA is worsened by aldosterone-mediated fluid retention." | 2.48 | Resistant hypertension and aldosterone: an update. ( Ahmed, MI; Calhoun, DA; Clark, D, 2012) |
| "Primary hyperaldosteronism (PHA) is characterized by an increased Aldosterone synthesis which is independent of the Renin-Angiotensin-Aldosterone-System (RAAS)." | 2.48 | [Primay hyperaldosteronism--diagnostic and treatment]. ( Beuschlein, F; Potthoff, SA; Vonend, O, 2012) |
| "Primary aldosteronism (PA) is an important cause of secondary hypertension, is being increasingly diagnosed and may account for more than 10% of hypertensive patients, both in primary care and in referral centers." | 2.47 | Treatment of primary aldosteronism: Where are we now? ( Karagiannis, A, 2011) |
| "Primary aldosteronism (PA) has been recognized as a common cause of secondary hypertension and accounts for approximately 5-15% of the hypertensive population in Japan." | 2.47 | Primary aldosteronism, diagnosis and treatment in Japan. ( Karashima, S; Takeda, Y; Yoneda, T, 2011) |
| "Diabetic nephropathy is the most common cause of end-stage renal disease in the western world." | 2.47 | The renin-angiotensin-aldosterone system and its blockade in diabetic nephropathy: main focus on the role of aldosterone. ( Schjoedt, KJ, 2011) |
| "Primary hyperaldosteronism will be the most common etiology." | 2.47 | [Primary hyperaldosteronism]. ( Chambaz, IC; Pechère-Bertschi, A, 2011) |
| "Aldosterone was in the past considered only as a prohypertensinogenic agent." | 2.46 | Aldosterone in uremia - beyond blood pressure. ( Koleganova, N; Ritz, E, 2010) |
| "The primary hyperaldosteronism (PHA) is the most prevalent form (8-10%) of secondary causes of hypertension among hypertensive subjects." | 2.45 | [Conn's syndrome]. ( Born-Frontsberg, E; Quinkler, M, 2009) |
| "Primary hyperaldosteronism is characterised by hypertension, hypokalemia, suppressed plasma renin activity, and increased aldosterone excretion." | 2.45 | Rhabdomyolysis due to primary hyperaldosteronism. ( Corrales, PP; López, AH; Martínez, JJ; Meneses, AL; Oliveira, CL; Rodríguez, SA; Romero, FB, 2009) |
| "Hyperaldosteronism is associated with endothelial dysfunction and impaired vascular reactivity in patients with hypertension or congestive heart failure." | 2.44 | Mineralocorticoid receptor antagonists and endothelial function. ( Leopold, JA; Maron, BA, 2008) |
| "Primary aldosteronism is one of the few potentially curable forms of hypertension." | 2.44 | Primary aldosteronism. ( Auchus, RJ; Nwariaku, FE, 2007) |
| "Primary aldosteronism is a much more common cause of secondary hypertension than once suspected, accounting for approximately 10% of cases." | 2.43 | The pharmacological treatment of primary aldosteronism. ( Bouloux, PM; Janmohamed, S, 2006) |
| "Resistant hypertension is defined as blood pressure that remains above target levels despite treatment with three different antihypertensive agents." | 2.43 | Aldosterone antagonists: effective add-on therapy for the treatment of resistant hypertension. ( Calhoun, DA; Gaddam, KK; Pratt-Ubunama, MN, 2006) |
| "The prevalence of primary hyperaldosteronism is 5-10% of all hypertensive patients, and clearly above the estimated prevalence in the past." | 2.43 | [Modern pharmacological aspects of hyperaldosteronism therapy]. ( Quinkler, M; Reincke, M, 2006) |
| "Aldosterone has direct effects on the vasculature and has been associated with vascular smooth muscle cell hypertrophy, endothelial dysfunction, cardiac fibrosis, proteinuria, and renal vascular injury." | 2.42 | Aldosterone: a risk factor for vascular disease. ( Fritsch Neves, M; Schiffrin, EL, 2003) |
| "Hyperaldosteronism in its various forms is a recognized secondary cause of hypertension, yet the frequency of these disorders and the appropriate evaluation of suspected patients remain controversial." | 2.42 | Aldo is back: recent advances and unresolved controversies in hyperaldosteronism. ( Auchus, RJ, 2003) |
| "Primary aldosteronism (PA) has been regarded for a long time as being a rare cause of arterial hypertension, but its prevalence has recently been reassessed as about 10%." | 2.42 | [Investigation of hyperaldosteronism in the hypertensive patient. Why? When? How?]. ( Amar, J; Chamontin, B; Herpin, D; Sosner, P, 2003) |
| "Adrenal cortical carcinoma is a rare endocrine tumor, and complete surgical resection is the only potentially curative treatment." | 2.41 | Adrenal cortical carcinoma. ( Boushey, RP; Dackiw, AP, 2001) |
| "Among 154 cases of primary aldosteronism seen in the General Clinical Research Center at San Francisco General Hospital, twelve patients did not fulfill established characteristics of an aldosterone producing adenoma (APA) or idiopathic hyperaldosteronism (IHA)." | 2.38 | Correctable subsets of primary aldosteronism. Primary adrenal hyperplasia and renin responsive adenoma. ( Biglieri, EG; Irony, I; Kater, CE; Shackleton, CH, 1990) |
| " Suitable techniques for the investigation of secondary aldosteronism of unknown cause and for primary and secondary hypoaldosteronism are described, as well as the adjustment of dosage for replacement therapy where mineralocorticoid secretion is deficient." | 2.37 | Disorders of mineralocorticoid activity. ( Drury, PL, 1985) |
| "Primary hyperaldosteronism (PA) is the most common secondary form of hyper-tension in middle-aged adults." | 1.91 | Best Practices: Indications and Procedural Controversies of Adrenal Vein Sampling for Primary Aldosteronism. ( Quencer, KB; Sharma, A; Singh, A, 2023) |
| "Primary aldosteronism is the underlying cause of hypertension in primary care settings in approximately 6% of cases, and it is even more common in patients with resistant hypertension." | 1.91 | Primary Aldosteronism. ( Quencer, KB; Rugge, JB; Senashova, O, 2023) |
| "Newly presenting hypertension is much the same-hold off on first-order antihypertensive(s) and prescribe spironolactone 25 mg/day for 4 weeks." | 1.91 | Who and How Should We Screen for Primary Aldosteronism? ( Funder, JW, 2023) |
| "Patients with primary aldosteronism (PA) have a high prevalence of microalbuminuria (MAU), which leads to more severe systemic vascular damage." | 1.62 | Long-term impact of spironolactone compliance on microalbuminuria in patients with primary aldosteronism. ( Hu, J; Li, N; Luo, Q; Wang, G; Wang, M; Wang, X; Zhang, D; Zhang, W, 2021) |
| "Primary aldosteronism (PA) is the most frequent form of endocrine hypertension." | 1.56 | Spironolactone reduces biochemical markers of bone turnover in postmenopausal women with primary aldosteronism. ( Adolf, C; Bidlingmaier, M; Braun, LT; Fuss, CT; Hahner, S; Handgriff, L; Heinrich, DA; Künzel, H; Reincke, M; Schneider, H; Sturm, L, 2020) |
| "Primary aldosteronism is associated with high cardiovascular morbidity and mortality due to activation of cardiac mineralocorticoid receptors." | 1.48 | Systolic heart failure in a patient with primary aldosteronism. ( Alvarez, C; Mohan, V, 2018) |
| "Renovascular hypertension is one of the common causes of secondary hypertension." | 1.48 | Unilateral renal artery stenosis presenting as acute flaccid paralysis: a rare presentation. ( Banerjee, S; Garg, K; Rajput, R; Singh, PK, 2018) |
| "Eplerenone treatment of patients with PA reduces blood pressure, increases serum potassium level, and improves vascular status." | 1.43 | Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism. ( Anzai, K; Kawate, H; Matsuda, Y; Matsuzaki, C; Nomura, M; Ohnaka, K; Sakamoto, R; Shibue, K; Takayanagi, R, 2016) |
| "KCNMB2(-/-) mice displayed hyperaldosteronism, normal plasma K(+) concentration, and produced dilute urine with decreased K(+) concentration." | 1.43 | Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice. ( Bleich, M; de Bruijn, PI; Jensen, IS; Larsen, CK; Leipziger, J; Praetorius, HA; Sorensen, MV, 2016) |
| "Treatment with spironolactone inhibited Akt/AS160 phosphorylation, reduced Rab-dependent Kv1." | 1.43 | Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice. ( Buschmeyer, B; Koehncke, C; Lisewski, U; Pieske, B; Roepke, TK; Wilck, N, 2016) |
| "Primary aldosteronism is associated with increased left ventricular (LV) mass independently of blood pressure." | 1.43 | Dietary Salt Intake Is a Determinant of Cardiac Changes After Treatment of Primary Aldosteronism: A Prospective Study. ( Bertin, N; Catena, C; Colussi, G; Novello, M; Pilz, S; Sechi, LA; Tomaschitz, A; Verheyen, ND, 2016) |
| "Treatment of primary aldosteronism (PA) aims at preventing or correcting hypertension, hypokalemia and target organ damage." | 1.43 | SFE/SFHTA/AFCE consensus on primary aldosteronism, part 6: Adrenal surgery. ( Amar, L; Chaffanjon, P; Kraimps, JL; Ménégaux, F; Steichen, O; Zinzindohoue, F, 2016) |
| "Primary aldosteronism (PA), the most common form of secondary hypertension, causes relevant morbidity." | 1.43 | The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism. ( Asbach, E; Bidlingmaier, M; Fourkiotis, V; Gerum, S; Lichtenauer, UD; Manolopoulou, J; Quinkler, M; Reincke, M, 2016) |
| "In experimental hyperaldosteronism, the increase in Gal-3 expression was associated with cardiac inflammation and fibrosis, alterations that were prevented by Gal-3 blockade independently of blood pressure levels." | 1.42 | Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension. ( Cachofeiro, V; Calvier, L; Fernández-Celis, A; Jaisser, F; Jurado-López, R; López-Andrés, N; Martínez-Martínez, E; Rossignol, P; Rossoni, LV; Rousseau, E; Zannad, F, 2015) |
| "Primary aldosteronism (PA, also Conn syndrome) is a benign disease in majority of cases." | 1.40 | Predictors of malignancy in primary aldosteronism. ( Agha, A; Haneya, A; Hornung, M; Iesalnieks, I; Jung, EM; Schlitt, HJ; Schreyer, A, 2014) |
| "Primary aldosteronism (PA) is one of the commonest forms of curable hypertension, and use of the plasma aldosterone-to-renin ratio as a screening test has led to a more efficient identification of this condition." | 1.39 | Mineralocorticoid receptor antagonists and renal involvement in primary aldosteronism: opening of a new era. ( Catena, C; Colussi, G; Sechi, LA, 2013) |
| "The incidence of left ventricular hypertrophy (LVH) in primary aldosteronism (PA) is higher than in essential hypertension." | 1.39 | Regression of left ventricular hypertrophy in patients with primary aldosteronism/low-renin hypertension on low-dose spironolactone. ( Bergman, M; Chagnac, A; Gafter, U; Herman-Edelstein, M; Korzets, A; Ori, Y; Salman, H; Zingerman, B, 2013) |
| "Primary aldosteronism (PA) is mainly caused by aldosterone-producing adenoma and idiopathic bilateral adrenal hyperplasia (IHA)." | 1.38 | Spontaneous remission of idiopathic aldosteronism after long-term treatment with spironolactone: results from the German Conn's Registry. ( Beuschlein, F; Bidlingmaier, M; Degenhart, C; Fischer, E; Jung, P; Reincke, M, 2012) |
| "Primary aldosteronism (PA) patients display an increased incidence of insulin resistance." | 1.38 | Genes implicated in insulin resistance are down-regulated in primary aldosteronism patients. ( Bertello, C; Fallo, F; Giraudo, G; Monticone, S; Mulatero, P; Urbanet, R; Veglio, F; Vettor, R; Williams, TA, 2012) |
| "Hyperaldosteronism combined with hypertension favored the macrophage infiltration (CD68(+) cells) in heart, and enhanced the mRNA level of monocyte chemoattractant protein 1, osteopontin, and galectin 3." | 1.38 | Aldosterone inhibits antifibrotic factors in mouse hypertensive heart. ( Azibani, F; Benard, L; Carrier, L; Chatziantoniou, C; Delcayre, C; Fazal, L; Launay, JM; Merval, R; Polidano, E; Samuel, JL; Schlossarek, S; Tournoux, F, 2012) |
| "Hyperaldosteronism is associated with vascular injury and increased cardiovascular events." | 1.37 | Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans. ( Bauersachs, J; Dietrich, B; Ertl, G; Fleissner, F; Hahner, S; Jazbutyte, V; Schmitter, K; Thum, T; Widder, JD; Wiebking, V, 2011) |
| "Kidney impairment is noted in primary aldosteronism (PA), and probably initiated by glomerular hyperfiltration." | 1.37 | Kidney impairment in primary aldosteronism. ( Chang, HW; Cheng, BW; Chiang, CK; Chiu, JS; Chu, TS; Chueh, SC; Ho, YL; Hu, FC; Huang, KH; Kuo, CC; Lin, CY; Lin, JW; Lin, LY; Lin, SL; Lin, YH; Liu, KL; Tsai, CT; Wang, SM; Wu, KD; Wu, VC; Yang, SY; Yen, RF, 2011) |
| "Thus, in rats with aldosteronism, in which a reduction in effective refractory period was not evident, the mechanism for VA susceptibility is presumably linked to a decrease in conduction velocity and/or increased dispersion of refractoriness, probably caused by consequential myocardial fibrosis." | 1.37 | Spironolactone prevents the inducibility of ventricular tachyarrhythmia in rats with aldosteronism. ( Bellary, SR; de Jongh Curry, AL; Deshmukh, PA; Kamalov, G; Magotra, M; Schwender, FT; Sun, Y; Weber, KT, 2011) |
| "Spironolactone treatment reversed all the above effects." | 1.37 | A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone. ( Cachofeiro, V; Díez, J; Fortuno, MA; Lahera, V; López-Andrés, N; Martin-Fernandez, B; Rossignol, P; Zannad, F, 2011) |
| "Resistant hypertension has evolved as an important global health care problem." | 1.37 | What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated? ( Sica, DA, 2011) |
| "No reports have described mycotic pseudoaneurysm in the aortic arch in a diabetic patient associated with primary aldosteronism." | 1.36 | Successful treatment of a mycotic aortic pseudoaneurysm in a patient with type 2 diabetes mellitus while treating primary aldosteronism with spironolactone. ( Fukata, M; Furukawa, H; Ito, H; Ito, Y; Konishi, T; Matsuzawa, Y; Nishikawa, T; Okura, K; Saito, J; Yoshimura, K, 2010) |
| " A maximal possible effect (E(max)) model was employed to determine the basic pharmacodynamic parameters of spironolactone, measured by high-performance liquid chromatography, in antagonizing the renal effects of aldosterone." | 1.36 | A preclinical pharmacokinetic and pharmacodynamic approach to determine a dose of spironolactone for treatment of congestive heart failure in dog. ( Elliott, J; Guyonnet, J; Kaltsatos, V, 2010) |
| "We recommend case detection of primary aldosteronism be sought in higher risk groups of hypertensive patients and those with hypokalemia by determining the aldosterone-renin ratio under standard conditions and that the condition be confirmed/excluded by one of four commonly used confirmatory tests." | 1.35 | Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. ( Carey, RM; Fardella, C; Funder, JW; Gomez-Sanchez, CE; Mantero, F; Montori, VM; Stowasser, M; Young, WF, 2008) |
| "Primary hyperaldosteronism (Conns' syndrome) commonly presents with a combi-nation of clinical features of hypokalemia and hypertension." | 1.35 | Conns' syndrome - atypical presentations. ( Hari Kumar, K; Jha, R; Jha, S; Modi, KD, 2009) |
| "Primary aldosteronism (PA) is the most common secondary cause of hypertension that has recently been implicated in alterations of the immune system and progression of cardiovascular disease." | 1.35 | Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha. ( Carvajal, CA; Castillo, CR; Contreras, FJ; Fardella, CE; Herrada, AA; Kalergis, AM; Mosso, LM; Stehr, CB, 2009) |
| "Patients with primary aldosteronism were compared with patients with essential hypertension and were treated to reach a blood pressure of less than 140/90 mm Hg." | 1.35 | Cardiovascular outcomes in patients with primary aldosteronism after treatment. ( Baroselli, S; Catena, C; Chiuch, A; Colussi, G; Lapenna, R; Nadalini, E; Sechi, LA, 2008) |
| "Primary hyperaldosteronism is a rare (<1%) and underdiagnosed cause of secondary hypertension." | 1.34 | Is primary hyperaldosteronism a risk factor for aortic dissection? ( Ahmed, SH; Husain, NM; Khawaja, SN; Massey, CV; Pettyjohn, FS, 2007) |
| "The aldosterone/renin ratio is a valid screening and sodium loading a valid confirmation test in GRA." | 1.34 | A German family with glucocorticoid-remediable aldosteronism. ( Altenhenne, C; Büchner, NJ; Dekomien, G; Epplen, JT; Hofebauer, S; Maser-Gluth, C; Rump, LC; Sellin, L; Vonend, O; Weiner, SM, 2007) |
| "Treatment of primary aldosteronism decreased blood pressure (BP) and restored normal potassium concentrations." | 1.34 | Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment. ( Baroselli, S; Bazzocchi, M; Catena, C; Chiuch, A; Colussi, GL; Lapenna, R; Nadalini, E; Novello, M; Sechi, LA, 2007) |
| "Primary aldosteronism (PA) is the most common secondary cause of hypertension and recently has been implicated as a cause of impaired glucose tolerance." | 1.34 | A possible association between primary aldosteronism and a lower beta-cell function. ( Artigas, RA; Carvajal, CA; Castillo, CR; Fardella, CE; Maiz, A; Mosso, LM; Ortiz, EH, 2007) |
| "Fifty-four patients with primary aldosteronism were enrolled in a prospective study and were followed for a mean of 6." | 1.34 | Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism. ( Catena, C; Chiuch, A; Colussi, G; Gianfagna, P; Lapenna, R; Nadalini, E; Sechi, LA, 2007) |
| "Spironolactone is an effective therapy for BAH and it is an adequate option for APA treatment when an adrenalectomy is not viable." | 1.33 | [Primary aldosteronism: analysis of a series of 54 patients]. ( Aliaga, L; Fernández-Torres, C; Jaén, F; Jiménez-Alonso, J; Mediavilla-García, JD; Sabio, JM, 2005) |
| "We followed up a girl with primary aldosteronism for 8 y, which was diagnosed at 6 y of age when she was referred to us for evaluation of heart murmur and growth failure." | 1.33 | Long-term follow-up of a girl with primary aldosteronism: effect of potassium supplement. ( Higashino, H; Hirose, Y; Isozaki, Y; Kobayashi, Y; Noda, Y; Takaya, J, 2005) |
| "Sixty-four patients with primary aldosteronism were included in the study." | 1.33 | Diurnal blood pressure pattern in patients with primary aldosteronism. ( Elenkova, A; Kalinov, K; Nachev, E; Orbetzova, M; Schigarminova, R; Stoynev, A; Yaneva, M; Zacharieva, S, 2006) |
| "Patients with primary aldosteronism were compared with 100 patients with essential hypertension, matched for severity and duration of hypertension." | 1.33 | Long-term renal outcomes in patients with primary aldosteronism. ( Baroselli, S; Catena, C; Colussi, GL; Lapenna, R; Nadalini, E; Novello, M; Sechi, LA, 2006) |
| "The incidence of primary aldosteronism in patients with difficult to treat hypertension is higher than previously stated in texts." | 1.32 | [Treatment refractory hypertension with atrophic kidney: attending to one and not neglecting the other]. ( Guertler, M; Suter, PM; Vetter, W, 2003) |
| "Primary hyperaldosteronism (PH) is frequently considered to be a secondary form of diabetes mellitus (DM)." | 1.32 | Does the treatment of primary hyperaldosteronism influence glucose tolerance? ( Sindelka, G; Skrha, J; Strauch, B; Widimský, J, 2003) |
| "Thus, aldosteronism is associated with an activation of circulating immune cells induced by iterations in PBMC divalent cations and transduced by oxidative/nitrosative stress." | 1.32 | Aldosteronism and peripheral blood mononuclear cell activation: a neuroendocrine-immune interface. ( Ahokas, RA; Bhattacharya, SK; Gerling, IC; Herring, PA; Lu, L; Postlethwaite, AE; Sun, Y; Warrington, KJ; Weber, KT; Wodi, LA, 2003) |
| "We report a rare case of adrenocortical carcinoma." | 1.32 | Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma. ( Azizlerli, H; Kapran, Y; Kurtulmus, N; Yarman, S, 2004) |
| "Treatment with losartan reverses this aldosterone-induced decrease in pump function, and coadministration with MR antagonists produces an additive effect on pump function, consistent with a beneficial effect of MR blockade in patients with hypertension and congestive heart failure treated with angiotensin type 1 receptor antagonists." | 1.31 | Mineralocorticoid and angiotensin receptor antagonism during hyperaldosteronemia. ( Funder, JW; Mardini, M; Mihailidou, AS; Raison, M, 2002) |
| "Primary aldosteronism is a common cause of non-renal secondary hypertension." | 1.31 | Normokalemic hyperaldosteronism in patients with resistant hypertension. ( Benchetrit, S; Bernheim, J; Podjarny, E, 2002) |
| "Only when the Cushing syndrome has been confirmed clinically and biochemically, should an imaging procedure be performed." | 1.31 | [Secondary forms of hypertension. 5. Hypertension caused by Cushing syndrome and Conn's disease]. ( Füessl, HS, 2002) |
| "Glucocorticoid-remediable aldosteronism (GRA) is a rarely recognised cause of arterial hypertension." | 1.30 | Abolished nocturnal blood pressure fall in a boy with glucocorticoid-remediable aldosteronism. ( Bernhardt, R; Hampf, M; Seeman, T; Widimský, J, 1999) |
| "We believe that primary hyperaldosteronism was a major pathogenetic factor in the formation of renal calculi since the increased urinary excretion of Ca++ and uric acid noted at onset declined following a short-term spironolactone administration and remission from renal calculi has persisted following initial nephrolithotomy and continued spironolactone therapy, which also corrected hypertension and hypokalemia, a hallmark of this disorder." | 1.29 | Renal calculi in primary hyperaldosteronism. ( Kabadi, UM, 1995) |
| "Since 1974 primary aldosteronism has been diagnosed in 71 patients in our outpatient clinic." | 1.29 | Primary aldosteronism: difference in clinical presentation and long-term follow-up between adenoma and bilateral hyperplasia of the adrenal glands. ( Erdmenger, L; Grüne, S; Jeck, T; Mengden, T; Vetter, W; Weisser, B, 1994) |
| "Spironolactone treatment (100 mg/daily) completely reversed the syndrome of mineralocorticoid excess." | 1.29 | Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism. ( Balsano, F; Bonavita, MS; Carlomagno, A; Coassin, S; De Siati, L; Falaschi, P; Ferri, C; Gualdi, G, 1994) |
| "In 30-40% of patients with primary aldosteronism owing to adenoma, hypertension is not relieved even though a hyper-functioning adenoma has been completely removed." | 1.29 | [The prediction of blood pressure after adrenalectomy in primary aldosteronism]. ( Ishibashi, K; Ishida, M; Ishida, T; Kanbe, M; Kido, K; Matsuura, H; Mitsuda, H; Oshima, T; Ozono, R; Watanabe, M, 1993) |
| "Primary hyperaldosteronism was detected in 1% of patients evaluated for secondary hypertension in a referral hospital in Southern India." | 1.29 | Primary hyperaldosteronism--diagnostic approach and management. ( Cherian, AM; Jesudason, SR; Kanagasabapathy, AS; Nair, A; Seshadri, MS, 1993) |
| "Spironolactone, however, was able to prevent myocardial fibrosis in RHT and aldosterone models of acquired arterial hypertension irrespective of the development of LVH and the presence of hypertension." | 1.29 | Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension. ( Brilla, CG; Matsubara, LS; Weber, KT, 1993) |
| "Twenty-eight patients with primary aldosteronism were treated from 1974 to 1990." | 1.28 | [Diagnosis and treatment of primary aldosteronism]. ( Wang, GY, 1992) |
| "Treatment with spironolactone alone, or in combination with either intravenous dopamine or ibopamine orally, amiloride, enalapril, hydralazine or clonidine corrected serum potassium values but failed to normalize blood pressure and to correct plasma renin activity and plasma aldosterone." | 1.28 | A neonate with idiopathic hyperaldosteronism. ( Derkx, FH; Donckerwolcke, RA; Griffiven, AW; Schalekamp, MA; Vande Walle, JG; Veenhoven, RH; Wit, JM, 1991) |
| "Two clinical cases of women with primary hyperaldosteronism are reported." | 1.28 | [2 cases of primary hyperaldosteronism]. ( Dodev, K; Kolarski, V; Nakov, N; Rashkov, R; Vladov, V, 1991) |
| "Four cases of pseudohyperaldosteronism due to chronic ingestion of liquorice-containing laxatives are described." | 1.28 | Pseudohyperaldosteronism from liquorice-containing laxatives. ( Armanini, D; Pratesi, C; Scali, M; Zampollo, V; Zennaro, MC, 1990) |
| "The treatment of Bartter's syndrome is fraught with difficulties, and there is no consensus concerning the pathogenetic mechanisms involved." | 1.28 | Bartter's syndrome--treatment with potassium, spironolactone and ACE-inhibitor. ( Christensen, P; Clementsen, P; Damkjaer, M; Giese, J; Hansen, CL; Høegholm, A, 1989) |
| "Treatment with spironolactone, mitotane, or aminoglutethimide had transient clinical effects." | 1.27 | Aldosterone-producing adrenocortical carcinoma. Preoperative recognition and course in three cases. ( Arteaga, E; Biglieri, EG; Kater, CE; Lopez, JM; Schambelan, M, 1984) |
| "Serum of patients with Bartter's syndrome incubated with healthy RBC distinctly increased their 86Rb influx." | 1.27 | The effect of long-term treatment with spironolactone on sodium pump abnormalities in the red blood cells of patients with Bartter's syndrome. ( Dvoráková, J; Horký, K; Schreiber, V, 1984) |
| "In other words, the Bartter's syndrome or the hypopotassemia should be one of the fundamental disorders for developing tetanic symptom." | 1.27 | [Development of tetany in siblings suffered from Bartter's syndrome]. ( Kimura, S; Kita, S; Okamoto, S; Shiozaki, Y; Suitsu, N, 1984) |
| "Spironolactone treatment normalized the arterial pressure in patients with primary aldosteronism at all Na intakes." | 1.27 | Effect of spironolactone on fluid volumes and adrenal steroids in primary aldosteronism. ( Hirano, Y; Ichikawa, S; Kogure, M; Matsuo, H; Murata, K; Sakamaki, T; Tajima, Y; Yagi, S, 1984) |
| "Spironolactone was administered in 6 of these patients, but not in the remaining patient." | 1.27 | Ultrastructural studies of adrenal adenoma causing primary aldosteronism. ( Kumazawa, J; Kuramoto, H, 1985) |
| "Biological primary aldosteronism was found post-operatively in 2 of these 3 patients and also in one whose hypertension was improved." | 1.27 | [Results of the surgical treatment of Conn's adenomas]. ( Chatellier, G; Corvol, P; Duclos, JM; Ménard, J; Pagny, JY; Plouin, PF, 1987) |
| "Secondary hyperaldosteronism produced by Na+ depletion was associated with increases in salt and fluid absorption in both the small intestine and the distal colon but not in the cecum and the proximal colon." | 1.27 | Amiloride-sensitive salt and fluid absorption in small intestine of sodium-depleted rats. ( Cortright, RN; Groseclose, RG; Hopfer, U; Will, PC, 1985) |
| "An unusual case of primary aldosteronism with bilateral single adenomas is reported." | 1.26 | Primary aldosteronism with bilateral adrenal adenomas. ( Favre, L; Hauser, H; Jacot-des-Combes, E; Mégevand, R; Morel, P; Riondel, AM; Vallotton, MB, 1980) |
| "In untreated patients with primary aldosteronism caused either by adrenal adenoma or hyperplasia plasma aldosterone and cortisol concentrations fluctuated in unison and dexamethasone reduced both hormones markedly." | 1.26 | Primary aldosteronism: effects of inhibition of ACTH and potassium administration on plasma aldosterone concentration. ( Ganguly, A; Luetscher, JA; Weinberger, MH, 1982) |
| "Thus, the present case of pseudoaldosteronism was attributed to Jintan, and raises a caution to excessive Jintan ingestion." | 1.26 | A case of pseudoaldosteronism due to addiction of Jintan, a mouth refresher popular among Japanese. ( Arakawa, K; Kamei, H, 1982) |
| "4." | 1.26 | The effect of mineralocorticoid administration on urine free dopamine in man. ( Lee, MR; Oates, NS; Perkins, CM, 1980) |
| "Hyperaldosteronism is an important factor contributing to fluid and sodium retention in infants with heart failure." | 1.26 | The occurrence of hyperaldosteronism in infants with congestive heart failure. ( Baylen, BG; Johnson, G; Kaplan, S; Srivastava, L; Tsang, R, 1980) |
| "Spironolactone was indicated preoperatively for all surgical candidates, for non-operated APA patients, and for all IHA patients." | 1.26 | Primary aldosteronism -- screening, diagnosis and therapy. ( Gregorová, I; Horký, K; Hradec, E; Silinková-Málková, E; Vancura, J, 1981) |
| "In primary aldosteronism the type of adrenal lesion was correctly identified in 28 of 40 patients (70%) by standard adrenal scintigraphy." | 1.26 | Adrenal scintigraphy in primary aldosteronism. Spironolactone as a cause of incorrect classification between adenoma and hyperplasia. ( Fischer, M; Vetter, H; Vetter, W; Winterg, B; Zidek, W, 1982) |
| " We conclude that aldosterone antagonists in the dosage used had no effect on the course of postoperative hyperaldosteronism." | 1.26 | Hyperaldosteronism after heart surgery in children. Part I: Treatment with aldosterone antagonists. ( Haschke, F; Parth, K; Wimmer, M, 1981) |
| "Potassium chloride was most effective in raising the serum potassium level during the first 4 weeks of administration." | 1.26 | Bartter's syndrome with normal urinary excretion of prostaglandin E: therapeutic effects of propranolol, spironolactone, indomethacin and potassium chloride. ( Abe, K; Chiba, S; Haruyama, T; Kabuki, J; Otsuka, Y; Saito, T; Sato, M; Yasujima, M; Yoshinaga, K, 1980) |
| "Idiopathic aldosteronism was usually treated by unilateral or subtotal adrenalectomy." | 1.26 | Results of treatment in 68 patients with idiopathic aldosteronism in Japan. ( Kumagai, A, 1980) |
| "Hyperparathyroidism and hyperaldosteronism coexisted in association with medullary sponge kidneys in a 27-year-old woman with severe hypertension." | 1.26 | Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension. ( Hellman, DE; Kartchner, M; Komar, N; Mayes, D; Pitt, M, 1980) |
| "Two cases of primary aldosteronism are described." | 1.26 | Primary aldosteronism. A report of 2 cases. ( Huddle, KR, 1981) |
| "The diagnosis of Bartter's syndrome was made in a 9-month-old boy investigated for poor weight and height gain." | 1.26 | Treatment of Bartter's syndrome in early childhood with prostaglandin synthetase inhibitors. ( Lee, MR; Littlewood, JM; Meadow, SR, 1978) |
| "When ibuprofen was added to this regimen, potassium supplements were no longer required." | 1.26 | Long-term use of propranolol, ibuprofen, and spironolactone in the management of Bartter's syndrome. ( Berger, M; Brouhard, BH; Cunningham, RJ; Petrusick, T; Travis, LB, 1979) |
| " The recommended dosage i." | 1.26 | [Experiences with aldactone in pediatric cardiology (author's transl)]. ( Bachl, G; Schlemmer, M; Stiskal, A; Wimmer, M, 1979) |
| "In an 18-year-old boy with Bartter's syndrome, hypophosphatemia was discovered (2." | 1.26 | Hypophosphatemia and hyperparathyroidism in a case of Bartter's syndrome. ( Bernheim, J; David, L; François, R; Sann, L, 1978) |
| "A 63-year-old man had asymptomatic Bartter's syndrome, discovered during evaluation for hypokalemia." | 1.26 | Asymptomatic Bartter's syndrome. ( Barbour, GL; Day, JO, 1978) |
| "Twenty patients suffering from primary hyperaldosteronism were studied." | 1.26 | [The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism]. ( Benguigui, L; Corvol, P; Houde, M; Menard, J; Milliez, P; Tonnelier, M, 1977) |
| "It is suggested that patients with Bartter's syndrome be treated simultaneously with large doses of spironolactone and a high sodium intake." | 1.25 | Bartter's syndrome. New insights into pathogenesis and treatment. ( Brown, RS; Solomon, RJ, 1975) |
| "The recognition of Conn's syndrome is important for that account as it coincides with an operatively curable hypertension." | 1.25 | Diagnosis and therapy of primary hyperaldosteronism in general practice. ( Bellin, H; Naumann, G; Schultz, J, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 384 (63.16) | 18.7374 |
| 1990's | 40 (6.58) | 18.2507 |
| 2000's | 82 (13.49) | 29.6817 |
| 2010's | 87 (14.31) | 24.3611 |
| 2020's | 15 (2.47) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T | 1 |
| Morimoto, S | 7 |
| Ichihara, A | 1 |
| Nikrýnová Nguyen, TMP | 1 |
| Štrauch, B | 4 |
| Petrák, O | 3 |
| Krátká, Z | 1 |
| Holaj, R | 3 |
| Kurcová, I | 1 |
| Marešová, V | 1 |
| Pilková, A | 1 |
| Hartinger, J | 1 |
| Waldauf, P | 1 |
| Zelinka, T | 3 |
| Widimský, J | 9 |
| Forestiero, V | 1 |
| Sconfienza, E | 1 |
| Mulatero, P | 3 |
| Monticone, S | 2 |
| Quencer, KB | 2 |
| Singh, A | 1 |
| Sharma, A | 1 |
| Mai, X | 3 |
| Kometani, M | 5 |
| Yoneda, T | 6 |
| Mandal, C | 1 |
| Dutta, PK | 1 |
| Rugge, JB | 1 |
| Senashova, O | 1 |
| Funder, JW | 5 |
| Park, W | 1 |
| Whitfield, P | 1 |
| Corley, B | 1 |
| Harper, S | 1 |
| Feltham, J | 1 |
| Carroll, R | 1 |
| Mikačić, I | 1 |
| Adolf, C | 1 |
| Braun, LT | 1 |
| Fuss, CT | 1 |
| Hahner, S | 2 |
| Künzel, H | 1 |
| Handgriff, L | 1 |
| Sturm, L | 1 |
| Heinrich, DA | 1 |
| Schneider, H | 1 |
| Bidlingmaier, M | 4 |
| Reincke, M | 9 |
| Lin, YF | 1 |
| Peng, KY | 1 |
| Chang, CH | 2 |
| Hu, YH | 1 |
| Wu, VC | 4 |
| Chung, SD | 1 |
| Wang, X | 1 |
| Luo, Q | 1 |
| Wang, M | 1 |
| Hu, J | 1 |
| Zhang, D | 1 |
| Zhang, W | 1 |
| Wang, G | 1 |
| Li, N | 1 |
| Ruilope, LM | 2 |
| Ruiz-Hurtado, G | 1 |
| Tamargo, J | 1 |
| Chan, CK | 1 |
| Chang, YY | 2 |
| Tsai, YC | 1 |
| Chen, ZW | 2 |
| Wu, CY | 1 |
| Huang, WC | 1 |
| Yen, IW | 1 |
| Wu, KH | 1 |
| Lin, YH | 3 |
| DeCarlo, KE | 1 |
| Agrawal, N | 1 |
| Morganti, A | 1 |
| Mancia, G | 1 |
| Stavropoulos, K | 1 |
| Imprialos, KP | 1 |
| Doumas, M | 2 |
| Athyros, VG | 3 |
| Karagiannis, A | 5 |
| Calhoun, DA | 7 |
| Nakano, Y | 1 |
| Yoshimoto, T | 1 |
| Fukuda, T | 1 |
| Murakami, M | 3 |
| Bouchi, R | 1 |
| Minami, I | 1 |
| Hashimoto, K | 1 |
| Fujii, Y | 1 |
| Kihara, K | 1 |
| Ogawa, Y | 1 |
| Pilz, S | 3 |
| Trummer, C | 1 |
| Verheyen, N | 2 |
| Schwetz, V | 1 |
| Pandis, M | 1 |
| Aberer, F | 1 |
| Grübler, MR | 1 |
| Meinitzer, A | 1 |
| Bachmann, A | 1 |
| Voelkl, J | 1 |
| Alesutan, I | 1 |
| Catena, C | 10 |
| Sechi, LA | 10 |
| März, W | 2 |
| Obermayer-Pietsch, B | 1 |
| Tomaschitz, A | 3 |
| Alvarez, C | 1 |
| Mohan, V | 1 |
| Choy, KW | 1 |
| Singh, PK | 1 |
| Rajput, R | 1 |
| Banerjee, S | 1 |
| Garg, K | 1 |
| Naito, T | 1 |
| Hagiya, H | 1 |
| Nakagami, F | 1 |
| Yamamoto, K | 1 |
| Liang, K | 1 |
| Ou, X | 1 |
| Huang, X | 1 |
| Lan, Q | 1 |
| Hill, MA | 1 |
| Sowers, JR | 1 |
| Kakoki, M | 1 |
| Pochynyuk, OM | 1 |
| Hathaway, CM | 1 |
| Tomita, H | 1 |
| Hagaman, JR | 1 |
| Kim, HS | 1 |
| Zaika, OL | 1 |
| Mamenko, M | 1 |
| Kayashima, Y | 1 |
| Matsuki, K | 1 |
| Hiller, S | 1 |
| Li, F | 1 |
| Xu, L | 1 |
| Grant, R | 1 |
| Bertorello, AM | 1 |
| Smithies, O | 1 |
| Weiner, ID | 2 |
| Petramala, L | 1 |
| Savoriti, C | 1 |
| Zinnamosca, L | 1 |
| Marinelli, C | 1 |
| Settevendemmie, A | 1 |
| Calvieri, C | 1 |
| Catani, M | 1 |
| Letizia, C | 1 |
| Agha, A | 1 |
| Hornung, M | 1 |
| Iesalnieks, I | 1 |
| Schreyer, A | 1 |
| Jung, EM | 1 |
| Haneya, A | 1 |
| Schlitt, HJ | 1 |
| Ritz, E | 2 |
| Pieske, B | 2 |
| Rus-Machan, J | 1 |
| Kienreich, K | 1 |
| Gaksch, M | 1 |
| Grübler, M | 1 |
| Fahrleitner-Pammer, A | 1 |
| Mrak, P | 1 |
| Toplak, H | 1 |
| Kraigher-Krainer, E | 1 |
| Brown, JM | 1 |
| Williams, JS | 1 |
| Luther, JM | 1 |
| Garg, R | 1 |
| Garza, AE | 1 |
| Pojoga, LH | 1 |
| Ruan, DT | 1 |
| Williams, GH | 2 |
| Adler, GK | 1 |
| Vaidya, A | 1 |
| Adachi, M | 1 |
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| Holmes, AM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP)[NCT04150666] | 0 participants (Actual) | Interventional | 2019-12-01 | Withdrawn (stopped due to No subjects are willing to participating.) | |||
| Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications[NCT01406015] | 38 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
| Aldosterone and Glucose Homeostasis[NCT00732160] | 34 participants (Actual) | Interventional | 2008-09-30 | Completed | |||
| Caveolin-1 and Vascular Dysfunction[NCT01426529] | Phase 1 | 120 participants (Anticipated) | Interventional | 2010-10-01 | Active, not recruiting | ||
| Salt Sensitive Hypertension and Striatin[NCT03683069] | Phase 4 | 400 participants (Actual) | Interventional | 2019-01-15 | Active, not recruiting | ||
| Unilateral Primary Aldosteronism, Mineralocorticoid Antagonists Versus Surgical Treatment - A Randomized Controlled Trial[NCT05797558] | 80 participants (Anticipated) | Interventional | 2023-04-28 | Recruiting | |||
| 68Ga-Pentixafor PET/CT for the Subtyping Diagnosis of Primary Aldosteronism: A Prospective Diagnostic Accuracy Study[NCT05131061] | 100 participants (Actual) | Observational | 2021-11-11 | Completed | |||
| Effects of Mineralocorticoid and AT-1 Receptor Antagonism on the Aldosterone-Renin Ratio (ARR) In Primary Aldosteronism Patients (EMIRA Study): Rationale and Design[NCT04185857] | 50 participants (Actual) | Observational | 2018-01-01 | Completed | |||
| Prospective Cross-sectional Study on Prevalence of Primary Aldosteronism in Resistant Hypertension and Association With Cardiometabolic Complications[NCT04213963] | 100 participants (Anticipated) | Observational | 2011-09-01 | Recruiting | |||
| The Intra-Procedural Cortisol Assay During Adrenal Vein Sampling: Rationale andDesign of A Randomized Study (I-PADUA)[NCT03449797] | 200 participants (Anticipated) | Interventional | 2018-04-01 | Not yet recruiting | |||
| Prospective Assessment of The Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation[NCT01267747] | 411 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension[NCT01996449] | Phase 2 | 14 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
| The Prevalence and the Prognosis of Resistant Hypertension Ascertained With Systemic Investigation and Optimal Treatment With Antihypertensive Drugs[NCT01703780] | 9,638 participants (Actual) | Observational | 2012-07-31 | Active, not recruiting | |||
| Aldosterone-Renin Ratio to Diagnose Primary Aldosteronism in a Population of Patients With Therapy-Resistant Hypertension: Test Characteristics, Diagnostic Value and Predictive Value for Antihypertensive Treatment. The Dutch ARRAT Study.[NCT00407784] | 500 participants | Observational | 2007-01-31 | Recruiting | |||
| Characteristics Predicting Clinically Relevant Reduction of Hypertension Following Adrenalectomy for Primary Aldosteronism: a Multicenter Analysis[NCT04761354] | 514 participants (Actual) | Observational | 2016-03-26 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Insulin resistance was measured using the 75 G glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 mL of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. HOMA-IR was calculated using the Insulin and glucose levels obtained. A negative change (decrease in insulin resistance) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)
| Intervention | IR index (Mean) | |
|---|---|---|
| Baseline | Change from Baseline at Week 6 | |
| Placebo | 3.4 | 0.1 |
| Spironolactone | 2.7 | 0.1 |
Insulin sensitivity was measured using the 75 gram (G) glucose tolerance test. Participants ingested 75 grams of glucose in 300-400 milliliters (mL) of water over 5 minutes. Blood samples were taken before ingesting glucose and then every 30 minutes for 120 minutes. Insulin sensitivity index was calculated by Matsuda and Defronzo's formula using the values obtained. A positive change from Baseline (increase in insulin sensitivity) indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to ingesting glucose and every 30 minutes for 120 minutes)
| Intervention | IS index (Mean) | |
|---|---|---|
| Baseline | Change from Baseline at Week 6 | |
| Placebo | 4.6 | -1.1 |
| Spironolactone | 3.7 | -0.1 |
Renal plasma blood flow was determined by clearance of para-aminohippurate (PAH). A loading dose of PAH (8 mg/kg) was given intravenously followed by a 1 hour constant infusion of PAH at a rate of 12 mg/minute (min). Plasma samples were obtained at Baseline and at 50 and 60 minutes. PAH clearance was calculated from the plasma levels and infusion rates and reported in millimeters (mL)/minute (min). A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6 (Prior to PAH infusion and at 50 and 60 minutes post PAH infusion)
| Intervention | mL/min (Mean) | |
|---|---|---|
| Baseline | Change from Baseline at Week 6 | |
| Placebo | 521 | -5.2 |
| Spironolactone | 488 | -2.3 |
Ultrasonography of the brachial artery was performed to evaluate endothelial function by flow mediated dilatation (FMD) studies. A blood pressure cuff was placed on the participant's upper arm and was compressed for 5 minutes. After release of compression, brachial artery diameter and blood flow velocity were measured. FMD was expressed as the percentage change in brachial artery diameter. A positive change from Baseline indicates improvement. (NCT01406015)
Timeframe: Baseline and Week 6
| Intervention | percent dilalation (Mean) | |
|---|---|---|
| Baseline | Change from Baseline at Week 6 | |
| Placebo | 10.2 | -2.0 |
| Spironolactone | 9.6 | -1.2 |
Acute Insulin response during Hyperglycemic clamp (delta insulin uU/mL, t=0-10) (NCT00732160)
Timeframe: 3 hours
| Intervention | uU/mL (Mean) |
|---|---|
| Vehicle, HS | 48.9 |
| Vehicle, LS | 37.6 |
| Aldosterone, HS | 51.8 |
| Aldosterone, LS | 34.4 |
Insulin sensitivity index (ISI) was calculated by dividing the average glucose infusion rate (mg glucose infusion/kg body weight/min) by the average insulin concentration (uU/mL) from 90 to 120 minutes. This was multiplied by 100 (thus, x100 in units description), per reporting convention in literature. (NCT00732160)
Timeframe: 3 hours
| Intervention | mg/kg/min per uU/mL*100 (Mean) |
|---|---|
| Vehicle, HS | 25.2 |
| Vehicle, LS | 24.8 |
| Aldosterone, HS | 23.4 |
| Aldosterone, LS | 24.7 |
measurement of sympathetic nerve activity by microneurography (intraneural microelectrodes) (NCT01996449)
Timeframe: 8 weeks post treatment initiation
| Intervention | bursts/minute (Mean) |
|---|---|
| Amlodipine | 41 |
| Eplerenone | 43.8 |
measurement of sympathetic nerve activity by microneurography (intraneural microelectrodes) during arm cycling exercise (NCT01996449)
Timeframe: 8 weeks post treatment initiation
| Intervention | bursts/minute (Mean) |
|---|---|
| Amlodipine | 47 |
| Eplerenone | 51 |
89 reviews available for spironolactone and Hyperaldosteronism
| Article | Year |
|---|---|
Primary aldosteronism in pregnancy.
Topics: Eplerenone; Female; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists | 2023 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Spontaneous Remission of Primary Aldosteronism with Mineralocorticoid Receptor Antagonist Therapy: A Review.
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; | 2022 |
Taiwan mini-frontier of primary aldosteronism: Updating treatment and comorbidities detection.
Topics: Adrenalectomy; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spi | 2021 |
Resistant hypertension: Renal denervation or intensified medical treatment?
Topics: Antihypertensive Agents; Blood Pressure Determination; Denervation; Drug Resistance; Humans; Hyperal | 2018 |
Endocrine and hypertensive disorders of potassium regulation: primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Aldosterone; Eplerenone; Humans; Hy | 2013 |
Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease.
Topics: Adrenalectomy; Aldosterone; Animals; Bone Density; Bone Diseases; Calcium; Cardiovascular Diseases; | 2014 |
Discordant genotype-phenotype correlation in familial hyperaldosteronism type III with KCNJ5 gene mutation: a patient report and review of the literature.
Topics: Adrenal Glands; Amino Acid Substitution; Child, Preschool; G Protein-Coupled Inwardly-Rectifying Pot | 2014 |
Progress in primary aldosteronism: mineralocorticoid receptor antagonists and management of primary aldosteronism in pregnancy.
Topics: Animals; Disease Management; Eplerenone; Female; Humans; Hyperaldosteronism; Mineralocorticoid Recep | 2015 |
[Primary hyperaldosteronism: boundaries of diagnostics and therapy].
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocortical Hyperfunction; Aldos | 2014 |
Efficacy and safety of mineralocorticoid receptors in mild to moderate arterial hypertension.
Topics: Eplerenone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Random | 2015 |
Systematic review of surgery and outcomes in patients with primary aldosteronism.
Topics: Adrenalectomy; Epidemiologic Methods; Eplerenone; Humans; Hyperaldosteronism; Mineralocorticoid Rece | 2015 |
[Hypertension in the course of primary aldosteronism during pregnancy].
Topics: Acid Sensing Ion Channel Blockers; Aldosterone; Amiloride; Antihypertensive Agents; Eplerenone; Fema | 2015 |
Pharmacological treatment of aldosterone excess.
Topics: Aldosterone; Cytochrome P-450 CYP11B2; Dihydropyridines; Drug Interactions; Epithelial Sodium Channe | 2015 |
Third-generation Mineralocorticoid Receptor Antagonists: Why Do We Need a Fourth?
Topics: Animals; Drug Discovery; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Protein | 2016 |
Ankylosing spondylitis associated with primary aldosteronism in a middle-aged woman.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Biological Products; Biomarkers; Drug | 2017 |
[Aldosterone antagonists--first choice in resistant hypertension].
Topics: Adrenergic beta-Antagonists; Coronary Vasospasm; Diuretics, Potassium Sparing; Drug Therapy, Combina | 2016 |
Diagnosing and Managing Primary Aldosteronism in Hypertensive Patients: a Case-Based Approach.
Topics: Adrenalectomy; Eplerenone; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Laparoscopy; Mass | 2016 |
Mineralocorticoid receptor antagonists and endothelial function.
Topics: Aldosterone; Animals; Endocrine System Diseases; Endothelium, Vascular; Eplerenone; Humans; Hyperald | 2008 |
[Conn's syndrome].
Topics: Adrenalectomy; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spi | 2009 |
Rhabdomyolysis due to primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Female; Humans; Hyperaldosteronism; Hyperten | 2009 |
Aldosterone in uremia - beyond blood pressure.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Endothelial Cells; Endothelium, Vascular; | 2010 |
[Mineralocorticoid receptor antagonists: inhibition of the renin angiotensin system].
Topics: Albuminuria; Diabetes Mellitus, Type 2; Eplerenone; Female; Heart Failure; Humans; Hyperaldosteronis | 2010 |
Treatment of primary aldosteronism: Where are we now?
Topics: Adrenalectomy; Eplerenone; Humans; Hyperaldosteronism; Spironolactone | 2011 |
Primary aldosteronism, diagnosis and treatment in Japan.
Topics: Eplerenone; Humans; Hyperaldosteronism; Japan; Spironolactone | 2011 |
The renin-angiotensin-aldosterone system and its blockade in diabetic nephropathy: main focus on the role of aldosterone.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cyto | 2011 |
Aldosterone-induced fibrosis in the kidney: questions and controversies.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Antihypertensive Agents; Blood Pressure; Child, | 2011 |
[Primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Algorithms; Humans; Hyperaldosteronism; Hypertensi | 2011 |
Resistant hypertension and aldosterone: an update.
Topics: Aldosterone; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Hyperaldosteronis | 2012 |
[Primay hyperaldosteronism--diagnostic and treatment].
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Adenoma; A | 2012 |
[Resistant hypertension].
Topics: Age Factors; Aldosterone; Coronary Vasospasm; Disease Management; Diuretics; Humans; Hyperaldosteron | 2012 |
Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system.
Topics: Aldosterone; Animals; Cardiomegaly; Cardiovascular System; Heart Failure; Humans; Hyperaldosteronism | 2002 |
Aldosterone: a risk factor for vascular disease.
Topics: Aldosterone; Animals; Arteries; Fibrosis; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoi | 2003 |
Aldo is back: recent advances and unresolved controversies in hyperaldosteronism.
Topics: Eplerenone; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Incidence; Male; Re | 2003 |
[Investigation of hyperaldosteronism in the hypertensive patient. Why? When? How?].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Age of Onset; Female; Humans; Hyperaldosteronism; Hypertens | 2003 |
[SECONDARY HYPERALDOSTERONISM. PHYSIOPATHOLOGIC, CLINICAL AND THERAPEUTIC CONSIDERATIONS].
Topics: Adrenal Cortex Hormones; Angiotensins; Blood Transfusion; Capillary Permeability; Diet; Diet Therapy | 1963 |
ALDOSTERONE IN CLINICAL MEDICINE.
Topics: Aldosterone; Blood Volume; Body Weight; Desoxycorticosterone; Dexamethasone; Diuretics; Drug Therapy | 1964 |
Clinical manifestation of aldosteronoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Diagnosis, Differential; Humans; Hyperaldosteronism | 2004 |
Aldosterone antagonism: an emerging strategy for effective blood pressure lowering.
Topics: Eplerenone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spiron | 2005 |
[The latest developments in endocrinology 2004/2005].
Topics: Adrenal Gland Neoplasms; Adult; Bone Density Conservation Agents; Chronic Kidney Disease-Mineral and | 2006 |
The pharmacological treatment of primary aldosteronism.
Topics: Aldosterone; Amiloride; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combinatio | 2006 |
Aldosterone antagonists: effective add-on therapy for the treatment of resistant hypertension.
Topics: Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Miner | 2006 |
[Clinical characteristics of primary and secondary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Drug Therapy, Combination; E | 2006 |
[Idiopathic hyperaldosteronism (IHA)].
Topics: Adrenal Cortex; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Hyperplasia; Miner | 2006 |
[Modern pharmacological aspects of hyperaldosteronism therapy].
Topics: Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocortical Adenoma; Angiotensin II Type 1 Recept | 2006 |
[Treatment for symptoms of pseudoaldosteronism].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Diet, Sodium-Restricted; Glycyrrhiza; Glyc | 2007 |
Mechanisms and treatment of resistant hypertension.
Topics: Blood Pressure Monitoring, Ambulatory; Contraceptives, Oral; Diuretics; Drug Resistance; Humans; Hyp | 2007 |
Primary aldosteronism.
Topics: Adenoma; Heart Failure; Humans; Hyperaldosteronism; Mass Screening; Mineralocorticoid Receptor Antag | 2007 |
[Drug-induced pseudoaldosteronism].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Early Diagnosis; Glycyrrhiza; Glycyrrhizic Acid; Humans | 2007 |
The kinins and prostaglandins in hypertension.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Water; Dinoprost; Female; Furos | 1981 |
Primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Amiloride; Diagnosis, Differential; F | 1980 |
Primary aldosteronism--a review.
Topics: 18-Hydroxycorticosterone; Adenoma; Adolescent; Adrenal Glands; Adult; Aldosterone; Child; Humans; Hy | 1980 |
Pathogenesis of mineralocorticoid hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Aldosterone; Animals; Bloo | 1981 |
[Glucocorticoid-suppressible aldosteronism].
Topics: Glucocorticoids; Humans; Hyperaldosteronism; Spironolactone | 1993 |
[Hyperaldosteronism, spironolactone and liver cirrhosis].
Topics: Ascites; Humans; Hyperaldosteronism; Liver Cirrhosis; Renin-Angiotensin System; Spironolactone | 1997 |
[Differential diagnosis and therapy of primary hyperaldosteronism].
Topics: Adrenalectomy; Aldosterone; Diagnosis, Differential; Humans; Hyperaldosteronism; Mineralocorticoid R | 1998 |
Primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diagnosis, Differential; Humans; Hype | 1998 |
The spironolactone renaissance.
Topics: Aldosterone; Androgen Antagonists; Angiogenesis Inhibitors; Animals; Clinical Trials as Topic; Colla | 2001 |
Hyperaldosteronism: recent concepts, diagnosis, and management.
Topics: Aged; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; M | 2001 |
[Primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Algorithms; Amiloride; Di | 1998 |
Adrenal cortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adult; Algorithms; Antineoplastic Agents; Carcinoma; Chemot | 2001 |
Abnormal regulation of aldosterone in hypertension.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Circadian Rhythm; Diures | 1975 |
Spirolactones: clinical and pharmacologic studies.
Topics: Aldosterone; Animals; Binding, Competitive; Canrenoic Acid; Canrenone; Diuresis; Humans; Hyperaldost | 1977 |
Primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; | 1977 |
Bartter's syndrome.
Topics: Adrenalectomy; Bartter Syndrome; Humans; Hyperaldosteronism; Prostaglandin Antagonists; Prostaglandi | 1977 |
[Primary aldosteronism--aldosterone-induced sodium storing hypertension--symptoms and differential diagnosis].
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Alkalosis; Animals; Diagnosis, Differential; Dogs; F | 1979 |
Low renin hypertension.
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism | 1975 |
Mineralocorticoid receptor ligands: biochemical, pharmacological, and clinical aspects.
Topics: Addison Disease; Adrenal Cortex Hormones; Animals; Brain Chemistry; Canrenone; Drug Design; Hippocam | 1991 |
Correctable subsets of primary aldosteronism. Primary adrenal hyperplasia and renin responsive adenoma.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal | 1990 |
[Properties and indications of potassium-sparing diuretics].
Topics: Amiloride; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hy | 1986 |
Disorders of mineralocorticoid activity.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Specime | 1985 |
Assessment of adrenocortical function.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aldoster | 1971 |
Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; | 1973 |
[Hepatogenous (secondary) aldosteronism (author's transl)].
Topics: Aldosterone; Angiotensin II; Chronic Disease; Esophageal and Gastric Varices; Hepatitis; Hepatitis A | 1974 |
[Diagnosis and therapy of primary hyperaldosteronism].
Topics: Adrenal Gland Neoplasms; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; H | 1972 |
Aldosteronism updated.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differentia | 1973 |
The use of spironolactone in the diagnosis and the treatment of hypertension associated with mineralocorticoid excess.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Carc | 1973 |
Adrenal causes of hypertension.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Carci | 1974 |
Therapeutic alternatives in hypertension.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Carotid Sinus; Drug Resistance; Electric Stimulation; Human | 1973 |
[Present trends in the diagnosis of primary hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Desoxycorticosterone; Humans; Hyperaldosteronism; Pot | 1974 |
[Low renin essential hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin; Spironolactone; Trichlormet | 1973 |
Current management of primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Angiography; Humans; Hyperaldosteron | 1974 |
[New clinical application of spironolactone].
Topics: Adrenal Glands; Adult; Antihypertensive Agents; Ascites; Brain Edema; Diuretics; Edema; Female; Huma | 1974 |
Primary hyperaldosteronism.
Topics: Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Desoxycorticosterone; Electrocardiography; Hum | 1974 |
Juxtaglomerular cell hyperplasia and secondary hyperaldosteronism (Bartter's syndrome): a re-evaluation of the pathophysiology.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aldosterone; Child; Child, Preschool; Female; Humans; Hype | 1968 |
Commentary on incidence of primary aldosteronism: current estimations based on objective data.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Blood Pressure; Desoxycorticosterone; | 1969 |
[Role of aldosterone in the pathogenesis of cardiac insufficiency (review of the literature)].
Topics: Aldosterone; Animals; Cats; Chlorine; Depression, Chemical; Dogs; Edema; Heart Failure; Humans; Hype | 1967 |
[Steroid spirolactones--antagonists of mineralocorticoids].
Topics: Adrenalectomy; Animals; Ascites; Chemistry Techniques, Analytical; Desoxycorticosterone; Dogs; Feces | 1969 |
[Aldosterone and aldosterone antagonists in surgery].
Topics: Adult; Aldosterone; Blood Volume; Brain Edema; Cardiac Surgical Procedures; Child; Digitalis Glycosi | 1971 |
Combination diuretic drug therapy.
Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemid | 1971 |
24 trials available for spironolactone and Hyperaldosteronism
| Article | Year |
|---|---|
Effects of mineralocorticoid receptor antagonists on sex hormones and body composition in patients with primary aldosteronism.
Topics: Body Composition; Female; Gonadal Steroid Hormones; Humans; Hyperaldosteronism; Male; Mineralocortic | 2022 |
Mineralocorticoid Receptor Blockers and Aldosterone to Renin Ratio: A Randomized Controlled Trial and Observational Data.
Topics: Aged; Aldosterone; Double-Blind Method; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperparathy | 2018 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Rel | 2014 |
Long-term effects of adrenalectomy or spironolactone on blood pressure control and regression of left ventricle hypertrophy in patients with primary aldosteronism.
Topics: Adrenalectomy; Antihypertensive Agents; Blood Pressure; Electrocardiography; Female; Humans; Hyperal | 2015 |
Comparison of eplerenone and spironolactone for the treatment of primary aldosteronism.
Topics: Adult; Aged; Blood Pressure; Eplerenone; Female; Humans; Hyperaldosteronism; Kidney Function Tests; | 2016 |
Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.
Topics: Aldosterone; Bendroflumethiazide; Blood Pressure; Cross-Over Studies; Diuretics; Drug Therapy, Combi | 2010 |
Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: a prospective clinical study.
Topics: Age of Onset; Cardiac Volume; Creatinine; Diastole; Diuretics; Electrocardiography; Female; Heart; H | 2010 |
A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Eplerenone; Female; Humans; Hyperaldosteronism; | 2011 |
Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aged, 80 and over; Albuminuria; Blood Pressure; Creatinine; Eplerenone; | 2013 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Hyperaldosteronism among black and white subjects with resistant hypertension.
Topics: Adult; Aged; Aged, 80 and over; Alabama; Aldosterone; Black People; Blood Pressure; Diuretics; Drug | 2002 |
Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Administratio | 2008 |
[Hyperaldosteronism in the acute phase of myocardial infarction. Effects of its treatment on the prevention of ventricular fibrillation].
Topics: Acute Disease; Adult; Aged; Anti-Arrhythmia Agents; Canrenoic Acid; Clinical Trials as Topic; Female | 1984 |
Spironolactone and triamterene in volume-dependent essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1980 |
[Spironolactone in essential hypertension associated with abnormal aldosterone regulation and in Conn's syndrome (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertensi | 1980 |
Spironolactone prevents Na+/H+ exchange enhancement in primary aldosteronism.
Topics: Adult; Blood Pressure; Erythrocytes; Female; Humans; Hydrogen; Hyperaldosteronism; Hypertension; Mal | 1997 |
[Conn's syndrome. Study of systemic cardiovascular hemodynamics after medical treatment with spironolactone and after surgical treatment].
Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged | 1997 |
Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy.
Topics: Analysis of Variance; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Death, | 2000 |
Renin-aldosterone profiling in hypertension.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Clinical Trials as Topic; Diagnosis, Differential; D | 1977 |
[Search for ways to correct volemic disorders in thyrotoxicosis before surgery].
Topics: Aldosterone; Blood Volume; Circadian Rhythm; Clinical Trials as Topic; Drug Evaluation; Humans; Hype | 1977 |
Carbenoxolone sodium for gastric ulcer.
Topics: Benzothiadiazines; Body Weight; Carbenoxolone; Clinical Trials as Topic; Diuretics; Duodenal Ulcer; | 1975 |
Comparative clinical study of spironolactone and potassium canrenoate. A randomized evaluation with double cross-over.
Topics: Aldosterone; Canrenoic Acid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperald | 1988 |
Assessment of the antimineralocorticoid effect of RU 28318 in healthy men with induced exogenous and endogenous hypermineralocorticism.
Topics: Adult; Aldosterone; Clinical Trials as Topic; Double-Blind Method; Fludrocortisone; Furosemide; Huma | 1985 |
Does prolonged pretreatment with large doses of spironolactone hasten a recovery from juxtaglomerular-adrenal suppression in primary aldosteronism?
Topics: Adolescent; Adrenal Glands; Adult; Blood Pressure; Clinical Trials as Topic; Diet, Sodium-Restricted | 1970 |
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-R | 1970 |
495 other studies available for spironolactone and Hyperaldosteronism
| Article | Year |
|---|---|
Adherence and blood pressure control in patients with primary aldosteronism.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Eplerenone; Fe | 2022 |
Best Practices: Indications and Procedural Controversies of Adrenal Vein Sampling for Primary Aldosteronism.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Humans; Hyperaldosteronism; Middl | 2023 |
Unique Case of Cardiomyopathy Secondary to Adrenal Adenoma (Primary-Aldosteronism).
Topics: Adenoma; Adrenocortical Adenoma; Aldosterone; Cardiomyopathies; Female; Humans; Hyperaldosteronism; | 2023 |
Primary Aldosteronism.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Renin; Spironolactone | 2023 |
Who and How Should We Screen for Primary Aldosteronism?
Topics: Aldosterone; Antihypertensive Agents; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Reni | 2023 |
Increasing rates of referrals for investigation of primary aldosteronism at a tertiary centre.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Ant | 2023 |
An unmet medical need vs. regulatory recommendations: how should we treat patients with hyperaldosteronism and advanced chronic kidney disease when surgery is not feasible?
Topics: Adult; Humans; Hyperaldosteronism; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Renal | 2020 |
Spironolactone reduces biochemical markers of bone turnover in postmenopausal women with primary aldosteronism.
Topics: Alkaline Phosphatase; Biomarkers; Bone Density; Bone Remodeling; Female; Humans; Hyperaldosteronism; | 2020 |
Changes in Glucose Metabolism after Adrenalectomy or Treatment with a Mineralocorticoid Receptor Antagonist for Primary Aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Blood Glucose; Fasting; Female; Humans; Hyperaldosteronism; | 2020 |
Long-term impact of spironolactone compliance on microalbuminuria in patients with primary aldosteronism.
Topics: Albuminuria; Humans; Hyperaldosteronism; Medication Adherence; Spironolactone; Treatment Outcome | 2021 |
Editorial commentary: Adequate blood pressure control unattainable without adequate recognition and treatment of primary aldosteronism.
Topics: Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Spironolactone | 2022 |
Double hit! A unique case of resistant hypertension.
Topics: Adrenal Glands; Aldosterone; Diuretics; Female; Humans; Hyperaldosteronism; Hyperparathyroidism, Pri | 2017 |
Subclinical target organ damage in primary aldosteronism: resistant to spironolactone therapy?
Topics: Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Spironolactone | 2018 |
Reply.
Topics: Humans; Hyperaldosteronism; Spironolactone | 2018 |
Medical Versus Surgical Treatment of Primary Aldosteronism.
Topics: Adrenalectomy; Atrial Fibrillation; Humans; Hyperaldosteronism; Spironolactone | 2018 |
Effect of Eplerenone on the Glomerular Filtration Rate (GFR) in Primary Aldosteronism: Sequential Changes in the GFR During Preoperative Eplerenone Treatment to Subsequent Adrenalectomy.
Topics: Adrenalectomy; Adult; Blood Pressure; Drug Administration Schedule; Eplerenone; Female; Glomerular F | 2018 |
Systolic heart failure in a patient with primary aldosteronism.
Topics: Adrenalectomy; Combined Modality Therapy; Heart Failure, Systolic; Humans; Hyperaldosteronism; Hyper | 2018 |
Investigation of primary aldosteronism in patients with resistant hypertension.
Topics: Amiloride; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Spironolactone | 2018 |
Unilateral renal artery stenosis presenting as acute flaccid paralysis: a rare presentation.
Topics: Antihypertensive Agents; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension, Renovasc | 2018 |
An uncommon cause of leg oedema.
Topics: Aged; Aldosterone; Edema; Female; Humans; Hyperaldosteronism; Hypokalemia; Leg; Magnetic Resonance I | 2019 |
Adrenocortical hypofunction with simultaneous primary aldosteronism: A case report.
Topics: Adrenal Insufficiency; Aged; Aldosterone; Cushing Syndrome; Female; Humans; Hydrocortisone; Hyperald | 2019 |
Mineralocorticoid antagonists and ENaC inhibitors in hyperaldosteronism.
Topics: Amiloride; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Spirono | 2019 |
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; DNA Primers; Gene Expression Regula | 2013 |
Primary aldosteronism and low-renin hypertension: a continuum?
Topics: Essential Hypertension; Female; Humans; Hyperaldosteronism; Hypertension; Hypertrophy, Left Ventricu | 2013 |
Primary aldosteronism with concurrent primary hyperparathyroidism in a patient with arrhythmic disorders.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Arrhythmias, Cardiac; Electr | 2013 |
Predictors of malignancy in primary aldosteronism.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Aged; Aldosterone; Cell Transformation, Neoplastic; Female; | 2014 |
Adrenal gland inclusions in patients treated with aldosterone antagonists (Spironolactone/Eplerenone): incidence, morphology, and ultrastructural findings.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aged; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperten | 2014 |
Long-term effect of specific treatment of primary aldosteronism on carotid intima-media thickness.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Blood Pressure; Carotid I | 2015 |
Unadjusted Plasma Renin Activity as a "First-Look" Test to Decide Upon Further Investigations for Primary Aldosteronism.
Topics: Adult; Aldosterone; Antihypertensive Agents; Body Mass Index; Female; Humans; Hyperaldosteronism; Hy | 2015 |
Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Galectin 3; Humans; Hyperal | 2015 |
Eplerenone improves carotid intima-media thickness (IMT) in patients with primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Atherosclerosis; Biomarkers; Carotid Intima-Media Thickness | 2016 |
Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice.
Topics: Aldosterone; Animals; Blood Pressure; Epithelial Sodium Channels; Eplerenone; Female; Hyperaldostero | 2016 |
Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice.
Topics: Adrenal Glands; Aldosterone; Animals; Atrial Fibrillation; Electrophysiological Phenomena; Gene Expr | 2016 |
Dietary Salt Intake Is a Determinant of Cardiac Changes After Treatment of Primary Aldosteronism: A Prospective Study.
Topics: Adrenalectomy; Adult; Analysis of Variance; Cohort Studies; Echocardiography, Doppler; Female; Follo | 2016 |
SFE/SFHTA/AFCE consensus on primary aldosteronism, part 6: Adrenal surgery.
Topics: Adrenalectomy; France; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Intraoperative Complic | 2016 |
SFE/SFHTA/AFCE primary aldosteronism consensus: Introduction and handbook.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Calcium Channel Blockers; France; Humans | 2016 |
SFE/SFHTA/AFCE consensus on primary aldosteronism, part 7: Medical treatment of primary aldosteronism.
Topics: Eplerenone; Female; France; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Mineralocor | 2016 |
ARAs to the RESCUE.
Topics: Aldosterone; Eplerenone; Gynecomastia; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Meta-A | 2016 |
The Clinical Value of Salivary Aldosterone in Diagnosis and Follow-Up of Primary Aldosteronism.
Topics: Adrenalectomy; Aged; Aldosterone; Case-Control Studies; Circadian Rhythm; Eplerenone; Female; Follow | 2016 |
Effects of Treating Primary Aldosteronism on Renal Function.
Topics: Adrenalectomy; Adult; Aldosterone; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; M | 2017 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.
Topics: Anti-Inflammatory Agents; Blood Pressure; Female; Fludrocortisone; Humans; Hyperaldosteronism; Hyper | 2008 |
Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.
Topics: Algorithms; Catheterization; Combined Modality Therapy; Cosyntropin; Diagnostic Techniques, Endocrin | 2008 |
Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.
Topics: Algorithms; Catheterization; Combined Modality Therapy; Cosyntropin; Diagnostic Techniques, Endocrin | 2008 |
Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.
Topics: Algorithms; Catheterization; Combined Modality Therapy; Cosyntropin; Diagnostic Techniques, Endocrin | 2008 |
Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.
Topics: Algorithms; Catheterization; Combined Modality Therapy; Cosyntropin; Diagnostic Techniques, Endocrin | 2008 |
Intrarenal hemodynamics in primary aldosteronism before and after treatment.
Topics: Adrenalectomy; Adult; Aged; Albuminuria; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; H | 2009 |
Conns' syndrome - atypical presentations.
Topics: Adrenalectomy; Adult; Blood Pressure; Diagnosis, Differential; Electrocardiography; Follow-Up Studie | 2009 |
Coupled calcium and zinc dyshomeostasis and oxidative stress in cardiac myocytes and mitochondria of rats with chronic aldosteronism.
Topics: Aldehydes; Aldosterone; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Dis | 2009 |
Hypertension of Kcnmb1-/- is linked to deficient K secretion and aldosteronism.
Topics: Analysis of Variance; Animals; Eplerenone; Hyperaldosteronism; Hyperkalemia; Hypertension; Kidney Tu | 2009 |
Primary aldosteronism can alter peripheral levels of transforming growth factor beta and tumor necrosis factor alpha.
Topics: Adult; Aldosterone; Cross-Sectional Studies; Female; Humans; Hyperaldosteronism; Hypertension; Inter | 2009 |
Update in primary aldosteronism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Amiloride; Antihypertensive Agents; Chromos | 2009 |
Spironolactone for all hypertensive patients?
Topics: Aldosterone; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Practic | 2010 |
Hyperaldosteronism is associated with a decrease in number and altered growth factor expression of endothelial progenitor cells in rats.
Topics: Animals; Cell Count; Cells, Cultured; Down-Regulation; Endothelial Cells; Hyperaldosteronism; Male; | 2011 |
Successful treatment of a mycotic aortic pseudoaneurysm in a patient with type 2 diabetes mellitus while treating primary aldosteronism with spironolactone.
Topics: Aged; Aneurysm, False; Aneurysm, Infected; Aortic Aneurysm; Blood Vessel Prosthesis Implantation; Di | 2010 |
A preclinical pharmacokinetic and pharmacodynamic approach to determine a dose of spironolactone for treatment of congestive heart failure in dog.
Topics: Animals; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Heart Failure; Hyperaldosteronism; Ma | 2010 |
Hyperaldosteronism and left ventricular hypertrophy.
Topics: Humans; Hyperaldosteronism; Hypertrophy, Left Ventricular; Insecticide-Treated Bednets; Spironolacto | 2010 |
46-year-old man with treatment-resistant hypertension.
Topics: Blood Pressure; Diagnosis, Differential; Diet, Sodium-Restricted; Drug Resistance; Follow-Up Studies | 2010 |
Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans.
Topics: Aldosterone; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Endo | 2011 |
Kidney impairment in primary aldosteronism.
Topics: Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Logistic Mode | 2011 |
[Diagnosis of secondary hypertension causing miscarriage during the first trimester of pregnancy].
Topics: Abortion, Spontaneous; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Antihypertensive Age | 2011 |
Ventricular repolarization before and after treatment in patients with secondary hypertension due to renal-artery stenosis and primary aldosteronism.
Topics: Adrenalectomy; Adult; Aged; Angioplasty; Blood Pressure; Electrocardiography; Female; Heart Ventricl | 2011 |
Spironolactone prevents the inducibility of ventricular tachyarrhythmia in rats with aldosteronism.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Collagen; Electric Stimulation; Electrocardiograp | 2011 |
Quality of life in patients with bilateral primary aldosteronism before and during treatment with spironolactone and/or amiloride, including a comparison with our previously published results in those with unilateral disease treated surgically.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Amiloride; Australia; Diuretics; Drug Therapy, Combination; | 2011 |
A role for cardiotrophin-1 in myocardial remodeling induced by aldosterone.
Topics: Aldosterone; Animals; Blood Pressure; Blotting, Western; Collagen; Cytokines; Disease Models, Animal | 2011 |
Spontaneous remission of idiopathic aldosteronism after long-term treatment with spironolactone: results from the German Conn's Registry.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Mineralocorti | 2012 |
What is the role of aldosterone excess in resistant hypertension and how should it be investigated and treated?
Topics: Aldosterone; Eplerenone; Female; Humans; Hyperaldosteronism; Hyperkalemia; Hypertension; Male; Miner | 2011 |
Eplerenone use in primary aldosteronism during pregnancy.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Eplerenone; Female; Follow-U | 2012 |
Unilateral primary aldosteronism with spontaneous remission after long-term spironolactone therapy.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Antihypertensive Agents; Cardiomegaly; Enalapril; Human | 2012 |
Predictive factors of left ventricular mass changes after treatment of primary aldosteronism.
Topics: Adrenalectomy; Adult; Aldosterone; Blood Pressure; Female; Heart Ventricles; Humans; Hyperaldosteron | 2012 |
Genes implicated in insulin resistance are down-regulated in primary aldosteronism patients.
Topics: Adipocytes; Adiponectin; Adult; Aged; Aldosterone; Carrier Proteins; Cells, Cultured; Down-Regulatio | 2012 |
Aldosterone inhibits antifibrotic factors in mouse hypertensive heart.
Topics: Aldosterone; Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blo | 2012 |
Endothelin-1 and adrenomedullin plasma levels after exposure to fludrocortisone, dexamethasone, and spironolactone.
Topics: Adrenal Insufficiency; Adrenomedullin; Adult; Anti-Inflammatory Agents; Biomarkers; Dexamethasone; D | 2012 |
Quality of life in patients with primary aldosteronism: gender differences in untreated and long-term treated patients and associations with treatment and aldosterone.
Topics: Adrenalectomy; Aged; Aldosterone; Female; Germany; Humans; Hyperaldosteronism; Male; Middle Aged; Mi | 2012 |
Overlapping spironolactone dosing in primary aldosteronism and resistant essential hypertension.
Topics: Aged; Diuretics; Humans; Hyperaldosteronism; Hypertension; Male; Potassium; Spironolactone | 2012 |
Mineralocorticoid receptor antagonists and renal involvement in primary aldosteronism: opening of a new era.
Topics: Eplerenone; Female; Humans; Hyperaldosteronism; Kidney; Male; Spironolactone | 2013 |
Idiopathic intracranial hypertension associated with either primary or secondary aldosteronism.
Topics: Adolescent; Adult; Aldosterone; Child; Electrolytes; Female; Humans; Hyperaldosteronism; Male; Middl | 2013 |
Regression of left ventricular hypertrophy in patients with primary aldosteronism/low-renin hypertension on low-dose spironolactone.
Topics: Aged; Blood Pressure Determination; Echocardiography; Essential Hypertension; Female; Follow-Up Stud | 2013 |
Mineralocorticoid and angiotensin receptor antagonism during hyperaldosteronemia.
Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Eplerenone; Heart Ventricles | 2002 |
Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone.
Topics: Aldosterone; Animals; Blood Pressure; Blotting, Northern; Carotid Arteries; Collagen; Collagen Type | 2002 |
[Treatment refractory hypertension with atrophic kidney: attending to one and not neglecting the other].
Topics: Adult; Antihypertensive Agents; Atrophy; Diagnosis, Differential; Drug Resistance; Drug Therapy, Com | 2003 |
[Conn syndrome as cause of stubborn hypertension. Which hypertensives should you screen?].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic beta-Antagonists; Aldosterone; Angiotens | 2003 |
Does the treatment of primary hyperaldosteronism influence glucose tolerance?
Topics: Adrenalectomy; Adult; Blood Glucose; Blood Pressure; Combined Modality Therapy; Female; Glucose Into | 2003 |
Efficacy of screening for primary aldosteronism by adrenocortical scintigraphy without discontinuing antihypertensive medication.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Biomarkers; Female; Humans; Hyperaldosteronism; J | 2003 |
[Conn's syndrome treated with spirolactone].
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Aldosterone; Diuretics; Hyperaldosteronism; Mineralocortico | 1961 |
[The effect of spirolactone SC-9420 in a case of secondary aldosteronism].
Topics: Aldosterone; Diuretics; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Spironolactone | 1961 |
[Initial results in the spirolactone treatment of 2 cases of the edematous syndrome with secondary aldosteronism].
Topics: Aldosterone; Diuretics; Edema; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Spironola | 1960 |
Primary aldosteronism. The value of spironolactone in diagnosis.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Lactones; Spirono | 1961 |
The diuretic effect of spirolactone SC-9420 in a case of secondary aldosteronism.
Topics: Aldosterone; Diuretics; Hyperaldosteronism; Spironolactone | 1960 |
[Conn's syndrome with adrenocortical adenoma. Action of spirolactone, SC-9420].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Diuretics; Humans; Hy | 1962 |
Correction of hyperaldosteronism and of massive fluid retention of unknown cause by sympathomimetic agents.
Topics: Amphetamine; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypotension; Hypotension, Orthostatic | 1962 |
Hypotensive effect of SC-9420 on 3 cases of primary aldosteronism.
Topics: Humans; Hyperaldosteronism; Potassium; Sodium; Spironolactone | 1962 |
Effect of aldosterone on the metabolism of magnesium.
Topics: Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Magnesium; Potassium; Spironolactone | 1962 |
[The hyperaldosteronism syndrome in edema caused by decompensated respiratory insufficiency and its treatment by spirolactones].
Topics: Diuretics; Edema; Humans; Hyperaldosteronism; Mineralocorticoid Receptor Antagonists; Pulmonary Emph | 1962 |
[Metabolic effects and clinical indications of spironolactone in secondary hyperaldosteronism].
Topics: Humans; Hyperaldosteronism; Spironolactone | 1963 |
[Cushing's syndrome, adiposity, hyperaldosteronism. Effect of spirolactone].
Topics: Adiposity; Cushing Syndrome; Humans; Hyperaldosteronism; Obesity; Spironolactone | 1963 |
[Clinical applications of spironolactone].
Topics: Ascites; Heart Failure; Humans; Hyperaldosteronism; Spironolactone | 1963 |
[Physiological bases of the utilization of aldosterone antagonists. Their clinical applications].
Topics: Heart Failure; Humans; Hyperaldosteronism; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; | 1962 |
[The effects of spironolactones in cardiac and hypertensive patients].
Topics: Heart Failure; Humans; Hyperaldosteronism; Hypertension; Spironolactone | 1963 |
[The clinical importance of spironolactones, peripheral antagonists of aldosterone].
Topics: Aldosterone; Edema; Humans; Hyperaldosteronism; Spironolactone; Water-Electrolyte Balance | 1961 |
HYPERALDOSTERONISM AND HYPERGRANULARITY OF THE JUXTAGLOMERULAR CELLS IN RENAL HYPERTENSION. METABOLIC STUDIES.
Topics: Alkalosis; Humans; Hyperaldosteronism; Hypertension, Renal; Hypokalemia; Kidney; Potassium; Renal Ar | 1963 |
MALIGNANT HYPERTENSION AND ALDOSTERONE SECRETION. INFLUENCE OF REVERSAL AND PROGRESSION OF THE SYNDROME IN TWO CASES.
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Spironolactone; Urem | 1963 |
SPIROLACTONE EFFECT ON POSTOPERATIVE ELECTROLYTES AND ADRENAL ACTIVITY.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Chlorides; Creatine; Creatinine; Electrolytes; Humans; Hyp | 1963 |
[ON USE OF THE BLOCKING AGENT ALDOSTERONE].
Topics: Aldosterone; Aortic Valve; Diuretics; Heart Failure; Humans; Hyperaldosteronism; Mitral Valve Insuff | 1963 |
[ENDOCRINOLOGICAL ASPECTS OF THE POTASSIUM DEPLETION SYNDROME].
Topics: Diuretics; Endocrine Glands; Heparin; Hyperaldosteronism; Hypokalemia; Liver Cirrhosis; Mineralocort | 1963 |
SECONDARY ALDOSTERONISM AND REFRACTORY OEDEMATOUS STATES.
Topics: Betamethasone; Biochemical Phenomena; Biochemistry; Diuretics; Edema; Heart Failure; Hepatitis; Huma | 1963 |
[TREATMENT OF STATES OF HYPERALDOSTERONISM. THERAPEUTIC INDICATIONS OF SPIRONOLACTONE].
Topics: Humans; Hyperaldosteronism; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Propiopheno | 1963 |
[TREATMENT BY SPIRONOLACTONE OF A FAMILIAL PERIODIC PARALYSIS WITH HYPERALDOSTERONISM].
Topics: Humans; Hyperaldosteronism; Paralyses, Familial Periodic; Paralysis; Spironolactone | 1963 |
[CLINICAL RESEARCH ON A NEW DIURETIC: TRIAMTERENE].
Topics: Ascites; Diabetes Insipidus; Diuretics; Edema; Humans; Hydrochlorothiazide; Hyperaldosteronism; Live | 1963 |
ALDOSTERONE AND SWEAT GLAND FUNCTION.
Topics: Acclimatization; Aldosterone; Dehydration; Hot Temperature; Humans; Hyperaldosteronism; Physiology; | 1963 |
HYPERTENSION DUE TO RENAL ARTERY OCCLUSION SIMULATING PRIMARY ALDOSTERONISM.
Topics: Aldosterone; Angiotensins; Blood Chemical Analysis; Blood Pressure; Hyperaldosteronism; Hypertension | 1964 |
[THE ALDOSTERONE ANTAGONISTS IN THE TREATMENT OF CIRRHOTIC ASCITIS].
Topics: Adrenal Cortex Hormones; Ascites; Diuresis; Hernia, Umbilical; Humans; Hyperaldosteronism; Liver Cir | 1963 |
PRIMARY ALDOSTERONISM IN PREGNANCY.
Topics: Adolescent; Black People; Clinical Laboratory Techniques; Diagnosis, Differential; Epistaxis; Female | 1964 |
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; | 1964 |
[PRIMARY ALDOSTERONISM (CONN SYNDROME)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Child; Diagnosis, Differential; Humans; Hyperaldost | 1964 |
THE DIAGNOSTIC IMPLICATION OF RESTRICTION OF SALT INTAKE AND ADMINISTRATION OF VARIOUS DRUGS IN PRIMARY ALDOSTERONISM.
Topics: Aldosterone; Biomedical Research; Cushing Syndrome; Desoxycorticosterone; Diagnosis, Differential; D | 1964 |
[THERAPY OF THE EDEMAS].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Edema; Hyperaldosteronism; Metabolism; Organomercury Compo | 1964 |
CLINICAL TRIAL OF TRIAMTERENE IN HYPERTENSIVE PATIENTS.
Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure Determination; Diuretics; Gout; Hyperal | 1964 |
[PLACE OF ALDACTONE IN THE THERAPY OF EDEMA].
Topics: Aldosterone; Edema; Heart Failure; Humans; Hyperaldosteronism; Liver Cirrhosis; Spironolactone | 1964 |
PRIMARY ALDOSTERONISM AND THE EFFECTS OF TWO MINERALOCORTICOID INHIBITORS--TRIAMTERENE AND SPIRONOLACTONE (ALDACTONE).
Topics: Adenoma; Adrenal Gland Neoplasms; Diuretics; Humans; Hyperaldosteronism; Mineralocorticoids; Patholo | 1964 |
[FURTHER OBSERVATIONS ON CONN'S SYNDROME].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Electrocardiography; Humans; Hyperaldosteronism; Hy | 1964 |
[ALDOSTERONE AND SPIROLACTONES IN THE CLINICAL TREATMENT OF INTERNAL DISEASES (REVIEW OF THE LITERATURE AND ANALYSIS OF PERSONAL CASES)].
Topics: Albuminuria; Aldosterone; Blood; Cardiovascular Diseases; Drug Therapy; Humans; Hyperaldosteronism; | 1963 |
[PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF SECONDARY ALDOSTERONISM AND ITS TREATMENT].
Topics: Adrenocorticotropic Hormone; Aldosterone; Ascites; Body Fluids; Classification; Dexamethasone; Extra | 1964 |
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL ADENOMA IN A THREE-YEAR-OLD CHILD.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Adenoma; | 1964 |
[CASE OF IDIOPATHIC EDEMA].
Topics: Blood Chemical Analysis; Edema; Humans; Hyperaldosteronism; Physiology; Psychosomatic Medicine; Spir | 1964 |
PRIMARY ALDOSTERONISM: OBSERVATIONS IN SIX CASES AND REVIEW OF DIAGNOSTIC PROCEDURES.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Diabetes Mellitus; Diagnosis, Differen | 1964 |
BILATERAL RENAL ARTERY STENOSIS WITH ALDOSTERONISM.
Topics: Angiography; Chlorides; Electrocardiography; Guanethidine; Heart Failure; Humans; Hyperaldosteronism | 1964 |
INTRACTABLE ASCITES.
Topics: Adrenal Cortex Hormones; Albumins; Ascites; Diet, Sodium-Restricted; Diuretics; Hyperaldosteronism; | 1964 |
CATHETERIZATION OF THE LEFT ADRENAL VEIN FOR CONTRAST INJECTION AND STEROID ANALYSIS IN A CASE OF CONN'S SYNDROME.
Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Angiography; Blood; | 1964 |
[THE SIGNIFICANCE OF SPIRONOLACTONE FOR THE DIAGNOSIS OF PRIMARY ALDOSTERONISM].
Topics: Diagnosis; Humans; Hyperaldosteronism; Inulin; Kidney Function Tests; p-Aminohippuric Acid; Spironol | 1964 |
IDIOPATHIC EDEMA ND HYPERALDOSTERONURIA: POSTURAL VENOUS PLASMA POOLING.
Topics: Adolescent; Aldosterone; Angiotensins; Blood Pressure; Body Weight; Drug Therapy; Edema; Ephedrine; | 1965 |
HYPOKALEMIA AND HYPERTENSION; A PRESENTATION OF FOUR CASES INCLUDING A CASE OF PRIMARY ALDOSTERONISM.
Topics: Adrenal Gland Neoplasms; Drug Therapy; Geriatrics; Heart Arrest; Humans; Hydroflumethiazide; Hyperal | 1964 |
HYPERTENSION AND HYPERALDOSTERONISM OF RENAL AND ADRENAL ORIGIN.
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Blood; Child; Diagnosis, | 1965 |
THE RELATIONSHIP BETWEEN VASCULAR REACTIVITY AND EXTRACELLULAR POTASSIUM.
Topics: Angiotensins; Blood Chemical Analysis; Blood Pressure; Blood Vessels; Body Weight; Chlorothiazide; C | 1965 |
EFFECTS OF SALT RESTRICTION, SPIRONOLACTONE, AND AMMONIUM CHLORIDE ON ACID-BASE RELATIONS IN A CASE OF PRIMARY ALDOSTERONISM.
Topics: Acid-Base Equilibrium; Adrenal Gland Neoplasms; Alkalosis; Ammonium Chloride; Blood; Diet, Sodium-Re | 1965 |
[ACTION OF SPIRONOLACTONE IN THE TREATMENT OF EDEMA OF SECONDARY ALDOSTERONISM].
Topics: Edema; Heart Failure; Humans; Hyperaldosteronism; Nephrotic Syndrome; Spironolactone | 1965 |
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL CARCINOMA.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Alkalosis; Blood; Drug Therapy; Hyperaldosteronism | 1965 |
[APROPOS OF A CASE OF CONN'S SYNDROME. THE DIFFERENTIAL DIAGNOSIS OF HYPERALDOSTERONISM WITH THE HELP OF DYNAMIC FUNCTION TESTS].
Topics: Albumins; Alkalosis; Angiotensins; Diagnosis, Differential; Hyperaldosteronism; Hypertension; Hypoka | 1964 |
CONN'S SYNDROME WITH ASSOCIATED PREGNANCY.
Topics: Adenoma; Adrenal Gland Neoplasms; Blood; Dexamethasone; Diagnosis; Female; Humans; Hyperaldosteronis | 1965 |
Primary aldosteronism. Preoperative preparation with spironolactone.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Aldosterone; Humans; Hyperaldosteronism; Mineralocorticoid | 1962 |
[Tissular aldactone saliuretic inhibitor of aldosterone. Its significance in the treatment of edemas associated with secondary hyperaldosteronism].
Topics: Aldosterone; Diuretics; Edema; Edetic Acid; Hyperaldosteronism; Spironolactone | 1961 |
Primary aldosteronism, diagnosed by the aldosterone to renin ratio, is a common cause of hypertension.
Topics: Aldosterone; Antihypertensive Agents; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hyperte | 2003 |
Aldosteronism and peripheral blood mononuclear cell activation: a neuroendocrine-immune interface.
Topics: Aldosterone; Animals; Calcium; Cell Separation; Coronary Vessels; Disease Models, Animal; Disease Pr | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Aldosterone; Female; F | 2003 |
Evaluation of high blood pressure in a 12-year-old girl.
Topics: Child; Dexamethasone; Diagnosis, Differential; Female; Glucocorticoids; Humans; Hyperaldosteronism; | 2004 |
Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aldosterone; Diuretics; Female; Histocyto | 2004 |
Hypokalemic quadriparesis with normotensive primary hyperaldosteronism.
Topics: Blood Pressure; Female; Humans; Hyperaldosteronism; Hypokalemia; Middle Aged; Mineralocorticoid Rece | 2004 |
[New potentialities in the treatment of idiopathic hyperaldosteronism].
Topics: Adrenal Glands; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; D | 2004 |
The neuroendocrine-immune interface gone awry in aldosteronism.
Topics: Aldosterone; Animals; Central Nervous System; Heart Failure; Humans; Hyperaldosteronism; Kidney; Min | 2004 |
A patient with concurrent primary hyperaldosteronism and adrenal insufficiency.
Topics: Adrenal Insufficiency; Aged; Humans; Hyperaldosteronism; Male; Mineralocorticoid Receptor Antagonist | 2004 |
Hyperparathyroidism and the calcium paradox of aldosteronism.
Topics: Aldosterone; Animals; Bone Density; Bone Resorption; Calcium; Hyperaldosteronism; Hyperparathyroidis | 2005 |
Relative glomerular hyperfiltration in primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aged; Blood Pressure; Female; Glomerular Filtration Rate; | 2005 |
[Primary aldosteronism: analysis of a series of 54 patients].
Topics: Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Anta | 2005 |
Conn's syndrome presenting as depression.
Topics: Adult; Depressive Disorder; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypokalemia; Male; | 2005 |
Diuretics and bone loss in rats with aldosteronism.
Topics: Animals; Bone Density; Calcium; Disease Models, Animal; Diuretics; Furosemide; Hyperaldosteronism; M | 2005 |
Bone loss in rats with aldosteronism.
Topics: Animals; Bone Resorption; Calcium; Hydrochlorothiazide; Hyperaldosteronism; Magnesium; Male; Parathy | 2005 |
Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans.
Topics: Adult; Aged; Aldosterone; Biomarkers; Blotting, Western; Case-Control Studies; Diuretics; Dose-Respo | 2005 |
Long-term follow-up of a girl with primary aldosteronism: effect of potassium supplement.
Topics: Adolescent; Blood Pressure; Body Height; Body Weight; Child; Child Development; Developmental Disabi | 2005 |
Bilateral renal artery stenosis and primary aldosteronism in a diabetic patient.
Topics: Adrenal Glands; Arteriosclerosis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; | 2005 |
Diurnal blood pressure pattern in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circa | 2006 |
Long-term renal outcomes in patients with primary aldosteronism.
Topics: Adrenalectomy; Adult; Albuminuria; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; H | 2006 |
[Normoaldosterone spironolactone sensitive hypertension--a case report].
Topics: Aged; Biomarkers; Diagnosis, Differential; False Positive Reactions; Female; Humans; Hyperaldosteron | 2005 |
[Normoaldosterone spironolactone sensitive hypertension].
Topics: Aged; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Spironolactone | 2006 |
Is primary hyperaldosteronism a risk factor for aortic dissection?
Topics: Antihypertensive Agents; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortography; Cardiac Catheter | 2007 |
Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism.
Topics: Administration, Oral; Aldosterone; Clinical Trials as Topic; Eplerenone; Gynecomastia; Humans; Hyper | 2007 |
Primary hyperaldosteronism in a patient with end-stage renal disease.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Follow-Up Studies; Fosinopril | 2007 |
A German family with glucocorticoid-remediable aldosteronism.
Topics: Adolescent; Aldosterone; Algorithms; Blood Pressure; Dexamethasone; Eplerenone; Female; Germany; Glu | 2007 |
Renal cysts and hypokalemia in primary aldosteronism: results of long-term follow-up after treatment.
Topics: Adrenalectomy; Aldosterone; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Hypokalemia | 2007 |
Zinc dyshomeostasis in rats with aldosteronism. Response to spironolactone.
Topics: Aldosterone; Animals; Coronary Vessels; Disease Models, Animal; Feces; Fibrosis; Homeostasis; Hypera | 2007 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang | 2007 |
A possible association between primary aldosteronism and a lower beta-cell function.
Topics: Aged; Aldosterone; Blood Glucose; C-Peptide; Case-Control Studies; Cholesterol; Female; Humans; Hype | 2007 |
Long-term cardiac effects of adrenalectomy or mineralocorticoid antagonists in patients with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aldosterone; Antihypertensive Agents; Female; Follo | 2007 |
Will the lessons from primary aldosteronism change the treatment of hypertension and left ventricular hypertrophy?
Topics: Adrenalectomy; Blood Pressure; Cohort Studies; Comorbidity; Follow-Up Studies; Humans; Hyperaldoster | 2007 |
Good blood pressure control on antihypertensives, not only response to spironolactone, predicts improved outcome after adrenalectomy for aldosteronoma.
Topics: Adrenalectomy; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cohort Studi | 2007 |
Cardiovascular outcomes in patients with primary aldosteronism after treatment.
Topics: Adrenalectomy; Adult; Aged; Aldosterone; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; | 2008 |
Aldosterone-to-renin ratio as a screening test for primary aldosteronism--the Dutch ARRAT Study.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Resistance; Eplerenone; Humans; Hyperaldoste | 2008 |
[Instinctive food selection as a disease-regulating factor].
Topics: Appetite; Autonomic Nervous System; Disease; Female; Food; Humans; Hunger; Hyperaldosteronism; Hypoc | 1966 |
Treatment of arterial hypertensive disease with diuretics. V. Spironolactone, an aldosterone antagonist.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Chlorthalidone; Female; Humans; Hyperaldost | 1967 |
Secondary aldosteronism in refractory edema.
Topics: Diuretics; Drug Synergism; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypokalemia; Liver Cirr | 1967 |
Bilateral adrenal hyperplasia as a cause of primary aldosteronism with hypertension, hypokalemia and suppressed renin activity.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Blood Urea Nitrogen; | 1967 |
A simple test to demonstrate pathologic secretion of aldosterone.
Topics: Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Potassium; Sodium; Spironolactone | 1967 |
Heterotopic adrenocortical adenoma producing primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Diagnosis, Differential; Diet, Sodium-Restricted; Female; H | 1967 |
Differential response to thiazides and spironolactone in primary aldosteronism.
Topics: Adult; Alkalosis; Blood Pressure; Diagnosis, Differential; Humans; Hydrochlorothiazide; Hyperaldoste | 1967 |
Changes in plasma renin activity after administration of spironolactone.
Topics: Adolescent; Adult; Aortic Coarctation; Blood Pressure; Cushing Syndrome; Female; Glomerulonephritis; | 1967 |
In vitro responses of aldosterone-producing adenomas to angiotensin II and ACTH after treatment with spironolactone before adrenalectomy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Angiotens | 1984 |
Aldosterone-producing adrenocortical carcinoma. Preoperative recognition and course in three cases.
Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Female; Glucocortico | 1984 |
The effect of long-term treatment with spironolactone on sodium pump abnormalities in the red blood cells of patients with Bartter's syndrome.
Topics: Adult; Aldosterone; Bartter Syndrome; Erythrocytes; Humans; Hyperaldosteronism; Ion Channels; Potass | 1984 |
[Treatment of hyperaldosteronism].
Topics: Adrenal Cortex Diseases; Canrenoic Acid; Female; Humans; Hyperaldosteronism; Male; Spironolactone | 1984 |
Primary aldosteronism with bilateral adrenal adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Aged; Female; Humans; Hyperaldosteronism; Inclusion Bodies; Neopla | 1980 |
Normotensive primary aldosteronism: report of a case.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Angiotensin II | 1981 |
Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Child, Preschool | 1981 |
Primary aldosteronism: effects of inhibition of ACTH and potassium administration on plasma aldosterone concentration.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aldoste | 1982 |
[Spironolactone bodies. Light and electron microscope study apropos of 4 cases of adrenal adenomas with primary hyperaldosteronism].
Topics: Adenoma; Adrenal Cortex Neoplasms; Humans; Hyperaldosteronism; Inclusion Bodies; Microscopy, Electro | 1982 |
Factors affecting the frequency of occurrence of spironolactone bodies in aldosteronomas and non-tumorous cortex.
Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Gland Neoplasms; Adult; Female; Humans; Hyperaldosteron | 1983 |
Pure primary hyperaldosteronism due to adrenal cortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Calcinosis; Carcinoma; Female; Humans; Hyperaldosteronism; Hypertension; H | 1984 |
Diagnosis of primary aldosteronism. Report of 2 cases with metabolic studies.
Topics: Adult; Female; Humans; Hyperaldosteronism; Kidney Tubules; Male; Potassium; Sodium; Spironolactone | 1983 |
A possible role of hypokalemia in the manifestation of high QRS voltage and sinus bradycardia in patients with primary aldosteronism.
Topics: Adult; Blood Pressure; Bradycardia; Electrocardiography; Female; Humans; Hyperaldosteronism; Hyperte | 1984 |
[Development of tetany in siblings suffered from Bartter's syndrome].
Topics: Adult; Bartter Syndrome; Biopsy; Calcium; Female; Humans; Hyperaldosteronism; Hypokalemia; Kidney; M | 1984 |
Effect of spironolactone on fluid volumes and adrenal steroids in primary aldosteronism.
Topics: Adrenal Cortex Hormones; Adult; Aged; Blood Pressure; Diet, Sodium-Restricted; Electrolytes; Extrace | 1984 |
Primary aldosteronism is comprised of primary adrenal hyperplasia and adenoma.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Ag | 1984 |
[Osteoporosis and prolonged administration of antialdosterone drugs. Histomorphometric study].
Topics: Adult; Calcifediol; Calcium; Drug Administration Schedule; Female; Fractures, Spontaneous; Humans; H | 1983 |
[Hypokalemic paralysis in a case with hyperthyroidism and idiopathic hyperaldosteronism].
Topics: Female; Humans; Hyperaldosteronism; Hyperthyroidism; Hypokalemia; Middle Aged; Paralysis; Periodicit | 1983 |
Plasma concentration and urinary excretion of arginine-vasopressin in primary aldosteronism during the fluid deprivation tests.
Topics: Adrenalectomy; Arginine Vasopressin; Diuresis; Humans; Hyperaldosteronism; Kidney Concentrating Abil | 1983 |
A case of pseudoaldosteronism due to addiction of Jintan, a mouth refresher popular among Japanese.
Topics: Captopril; Glycyrrhetinic Acid; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle | 1982 |
Recurrence of hypertension in primary aldosteronism after discontinuation of spironolactone. Time course of changes in cardiac output and body fluid volumes.
Topics: Aldosterone; Blood Pressure; Cardiac Output; Humans; Hyperaldosteronism; Hypertension; Potassium; Re | 1982 |
[Disorders of water and electrolyte equilibrium in liver diseases. Part 3: therapy (author's transl)].
Topics: Ascites; Benzothiadiazines; Canrenoic Acid; Diuretics; Humans; Hyperaldosteronism; Liver Diseases; S | 1982 |
The effect of mineralocorticoid administration on urine free dopamine in man.
Topics: Adult; Body Weight; Dopamine; Fludrocortisone; Humans; Hyperaldosteronism; Kidney; Male; Potassium; | 1980 |
The occurrence of hyperaldosteronism in infants with congestive heart failure.
Topics: Aldosterone; Body Weight; Epidemiologic Methods; Furosemide; Heart Failure; Humans; Hyperaldosteroni | 1980 |
Spironolactone and amiloride in hypertensive patients with and without aldosterone excess.
Topics: Adult; Amiloride; Blood Pressure; Body Weight; Female; Humans; Hyperaldosteronism; Hypertension; Mal | 1980 |
Familial, dexamethasone-suppressible, normokalemic hyperaldosteronism.
Topics: Adult; Aldosterone; Child; Circadian Rhythm; Dexamethasone; Humans; Hydroxycorticosteroids; Hyperald | 1980 |
Influence of spironolactone on aldosterone metabolism in hyperaldosteronism.
Topics: Aldosterone; Corticosterone; Humans; Hyperaldosteronism; Kinetics; Progesterone; Renin; Spironolacto | 1980 |
Influence of unilateral adrenalectomy on renin-angiotensin-aldosterone system in primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Angiotensins; Female; Humans; Hyperaldos | 1980 |
Bartter's syndrome: effect of indomethacin on prostaglandins, urinary kallikrein, renin-angiotensin-aldosterone system, and the response to angiotensin II antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Aminoglutethimide; Angiotensin II; Aspi | 1980 |
Combined captopril and spironolactone treatment in Conn's syndrome with renal impairment and refractory hypertension.
Topics: Adult; Angiotensin II; Captopril; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertensio | 1981 |
Primary aldosteronism -- screening, diagnosis and therapy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Humans; Hyperaldosteron | 1981 |
Bartter's syndrome.
Topics: Aldosterone; Bartter Syndrome; Brain Diseases, Metabolic; Child, Preschool; Electrolytes; Humans; Hy | 1981 |
Adrenal scintigraphy in primary aldosteronism. Spironolactone as a cause of incorrect classification between adenoma and hyperplasia.
Topics: 19-Iodocholesterol; Adenoma; Adosterol; Adrenal Gland Neoplasms; Adult; False Positive Reactions; Fe | 1982 |
Familial hyperaldosteronism, not suppressed by dexamethasone.
Topics: Adult; Blood Pressure; Child, Preschool; Dexamethasone; Female; Humans; Hydrocortisone; Hyperaldoste | 1982 |
Spironolactone bodies in aldosteronomas and in the attached adrenals. Enzyme histochemical study of 19 cases of primary aldosteronism and a case of aldosteronism due to bilateral diffuse hyperplasia of the zona glomerulosa.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Animals; Female; Histocytochemistry; Humans; | 1981 |
[An adrenal function test for general practice. Diagnosis of adrenal cortex insufficiency and primary and secondary hyperaldosteronism].
Topics: Adrenal Cortex Function Tests; Adrenal Insufficiency; Cosyntropin; Humans; Hyperaldosteronism; Hyper | 1981 |
Hyperaldosteronism after heart surgery in children. Part I: Treatment with aldosterone antagonists.
Topics: Adolescent; Aldosterone; Canrenoic Acid; Child; Child, Preschool; Heart Defects, Congenital; Hematoc | 1981 |
[Spironolactones in the treatment of arterial hypertension of different etiologies associated with hyperaldosteronism].
Topics: Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antago | 1981 |
Spironolactone hepatitis in primary hyperaldosteronism.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Hyperaldosteronism; Liver; Middle Aged; Spir | 1981 |
[Apropos of a case of Conn's disease. Use of computerized axial tomography in the differential diagnosis from hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Desoxycorticosterone; Dexamethasone; Diagnosis, Differentia | 1981 |
Effect of indomethacin in two siblings with a renin-dependent hypertension, hyperaldosteronism and hypokalemia.
Topics: Adolescent; Adult; Angiotensin II; Drug Therapy, Combination; Female; Humans; Hyperaldosteronism; Hy | 1980 |
Hyperaldosteronism associated with liver metastases.
Topics: Aldosterone; Alkaline Phosphatase; Ascites; Bilirubin; Edema; Female; Humans; Hyperaldosteronism; Li | 1980 |
Bartter's syndrome with normal urinary excretion of prostaglandin E: therapeutic effects of propranolol, spironolactone, indomethacin and potassium chloride.
Topics: Adult; Bartter Syndrome; Female; Humans; Hyperaldosteronism; Indomethacin; Male; Potassium Chloride; | 1980 |
Results of treatment in 68 patients with idiopathic aldosteronism in Japan.
Topics: Adolescent; Adrenal Glands; Adrenalectomy; Adult; Child, Preschool; Female; Humans; Hyperaldosteroni | 1980 |
Hyperaldosteronism, hyperparathyroidism, medullary sponge kidneys, and hypertension.
Topics: Adenoma; Adult; Aldosterone; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperparathyroidism | 1980 |
Nephropathologic characteristics of a woman with Bartter's syndrome after prolonged treatment with spironolactone.
Topics: Adult; Bartter Syndrome; Biopsy, Needle; Female; Humans; Hyperaldosteronism; Juxtaglomerular Apparat | 1980 |
Edema associated with laxative abuse and excessive diuretic therapy.
Topics: Adult; Cathartics; Diet, Sodium-Restricted; Diuretics; Edema; Ethacrynic Acid; Female; Foot Diseases | 1980 |
Primary aldosteronism. A report of 2 cases.
Topics: Adult; Electrocardiography; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Spironolactone | 1981 |
Renal calculi in primary hyperaldosteronism.
Topics: Humans; Hyperaldosteronism; Kidney Calculi; Male; Middle Aged; Nephrostomy, Percutaneous; Spironolac | 1995 |
Primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Diagnosis, Differential; Glucocorticoids; Humans; Hyperaldosteroni | 1994 |
Primary aldosteronism: difference in clinical presentation and long-term follow-up between adenoma and bilateral hyperplasia of the adrenal glands.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Diagnosis, Differential; Follow-Up St | 1994 |
Aldosterone regulation in primary aldosteronism.
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Spiro | 1994 |
Aldosterone response to adrenocorticotrophin and furosemide in primary aldosteronism after prolonged spironolactone treatment.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Female; Furosemide; Humans; Hyperaldosteronism; Mal | 1994 |
Interference by spironolactone on adrenocortical scintigraphy and other pitfalls in the location of adrenal abnormalities in primary aldosteronism.
Topics: Adosterol; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Dexamethasone; Humans; Hyperaldosteroni | 1994 |
Unilateral adrenal hypersecretion of both aldosterone and cortisol in two first cousins with a syndrome of mineralocorticoid excess but without signs of hypercortisolism.
Topics: Adrenal Glands; Adult; Aldosterone; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hyperplasia; | 1994 |
[The prediction of blood pressure after adrenalectomy in primary aldosteronism].
Topics: Adrenalectomy; Adult; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hyperaldosteronism; M | 1993 |
Primary hyperaldosteronism--diagnostic approach and management.
Topics: Adult; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hypokalemia; Male; Middle Aged; Nifedi | 1993 |
Effect of spironolactone on cytosolic free sodium concentration in platelets from hypertensive patients with primary aldosteronism.
Topics: Aged; Aged, 80 and over; Blood Platelets; Blood Pressure; Creatinine; Cytosol; Female; Humans; Hyper | 1993 |
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Hyperaldosteronism; Hypertension; | 1993 |
Alterations of calcium metabolism and of parathyroid function in primary aldosteronism, and their reversal by spironolactone or by surgical removal of aldosterone-producing adenomas.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Analysis | 1995 |
Prognostic factors of primary aldosteronism.
Topics: Adolescent; Adult; Aged; Blood Pressure; Child; Female; Follow-Up Studies; Humans; Hyperaldosteronis | 1996 |
Factors influencing outcome of surgery for primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aged; Blood Pressure; Female | 1996 |
[The clinical spectrum of potassium-sparing diuretics].
Topics: Aged; Antihypertensive Agents; Death, Sudden, Cardiac; Diuretics; Female; Humans; Hyperaldosteronism | 1997 |
Hyperkalaemia and diarrhoea in a patient with surreptitious ingestion of potassium sparing diuretics.
Topics: Chronic Disease; Diarrhea; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyper | 1997 |
Diuretics in congestive heart failure: new evidence for old problems.
Topics: Diuretics; Heart Failure; Humans; Hyperaldosteronism; Norepinephrine; Potassium; Sodium; Spironolact | 1999 |
Medical management of aldosterone-producing adenomas.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; | 1999 |
A syndrome resembling primary aldosteronism (Conn syndrome) in untreated HIV disease.
Topics: HIV Infections; Humans; Hyperaldosteronism; Male; Middle Aged; Mineralocorticoid Receptor Antagonist | 1999 |
Abolished nocturnal blood pressure fall in a boy with glucocorticoid-remediable aldosteronism.
Topics: Adolescent; Base Sequence; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Follow-Up Studie | 1999 |
[Factors for postoperative persistent hypertension in patients with aldosterone-producing adenoma].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Age Factors; Aldosterone; Female; Follow-Up Studies; Humans | 1997 |
Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Glucose; Glucose Clamp Technique; Glucos | 2000 |
Bilateral adrenal cortical hyperplasia.
Topics: Adult; Aldosterone; Diagnosis, Differential; Diuretics; Female; Humans; Hydrocortisone; Hyperaldoste | 2000 |
Cautions over idiopathic aldosteronism.
Topics: Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antago | 2001 |
Normokalemic hyperaldosteronism in patients with resistant hypertension.
Topics: Adult; Aged; Aldosterone; Analysis of Variance; Antihypertensive Agents; Creatinine; Female; Humans; | 2002 |
Primary aldosteronism: the most frequent form of secondary hypertension?
Topics: Aldosterone; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Mineral | 2002 |
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertens | 2001 |
Serum leptin levels in patients with primary hyperaldosteronism before and after treatment: relationships to insulin sensitivity.
Topics: Adrenal Glands; Adrenalectomy; Adult; Female; Glucose Clamp Technique; Humans; Hyperaldosteronism; H | 2002 |
[Secondary forms of hypertension. 5. Hypertension caused by Cushing syndrome and Conn's disease].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Algorithms; Cushing Sy | 2002 |
Hypertension, hypokalemia, hyporeninemia and severe target organ damage.
Topics: Aldosterone; Blood Pressure; Cardiomegaly; Female; Humans; Hyperaldosteronism; Hypertension; Hypokal | 1976 |
Antiandrogenic effect of spirolactones: mechanism of action.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Binding, Competitive; Canrenoic Acid; Cell Nucleus; | 1975 |
Spironolactone bodies in an adrenal adenoma.
Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Endoplasmic Reticulum; H | 1975 |
[Plasma-aldosterone and renin activity in Bartter's syndrome (author's transl)].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Bartter Syndrome; Dexamethasone; Glucocort | 1975 |
[A case of primary aldosteronism associated with spironolactone inclusions (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Canrenoic Acid; Female; Humans; Hyperaldosteronism; Inclusi | 1975 |
Plasma concentration of aldosterone, 18-hydroxy-deoxycorticosterone and cortisol in adrenal veins of patients with low-renin hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropi | 1977 |
Control of plasma aldosterone in a patient with Conn's syndrome before and during spironolactone medication.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Female; | 1975 |
Comparison of the urinary excretion of free aldosterone and its acid-labile conjugate in rats during experimental hyperaldosteronism.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Hyperaldosteronism; Male; Potassium; Radioimmunoa | 1979 |
Results of adrenal surgery in patients with hypertension, aldosterone excess, and low plasma renin concentration.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Angiotensin II; Blood Pres | 1975 |
Treatment of Bartter's syndrome in early childhood with prostaglandin synthetase inhibitors.
Topics: Bartter Syndrome; Body Height; Body Weight; Child, Preschool; Cyclooxygenase Inhibitors; Humans; Hyp | 1978 |
Value of the spironolactone test in the diagnosis of primary hyperaldosteronism.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; | 1979 |
Influence of spironolactone on serum corticosteroids in primary hyperaldosteronism.
Topics: Adrenal Cortex Hormones; Adult; Depression, Chemical; Humans; Hyperaldosteronism; Male; Middle Aged; | 1979 |
[Disorder of the mineralocorticoid function of the adrenals in the acute period of myocardial infarct and the ways for its correction].
Topics: Acute Disease; Adrenal Gland Diseases; Adult; Aged; Aldosterone; Chronic Disease; Coronary Disease; | 1979 |
The use of spironolactone for the diagnosis of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Female; Humans; Hyperaldosteronism; Male; Spironolactone | 1979 |
Long-term use of propranolol, ibuprofen, and spironolactone in the management of Bartter's syndrome.
Topics: Adolescent; Bartter Syndrome; Child; Child, Preschool; Drug Therapy, Combination; Growth; Humans; Hy | 1979 |
The significance of elevated levels of plasma 18-hydroxycorticosterone in patients with primary aldosteronism.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosteron | 1979 |
[Therapy of primary hyperaldosteronism].
Topics: Adrenalectomy; Aldosterone; Androgen Antagonists; Angiotensin II; Estrogen Antagonists; Female; Huma | 1979 |
Effects on muscle electrolytes of potassium and magnesium infusions, spironolactone medication and operation in a case of primary aldosteronism.
Topics: Female; Humans; Hyperaldosteronism; Infusions, Parenteral; Magnesium; Magnesium Deficiency; Membrane | 1979 |
[Plasma aldosterone and electrolytes in primary and secondard aldosteronism (author's transl)].
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Ascites; Electrolytes; Female; Humans; Hypera | 1979 |
Escape from sodium and potassium retaining actions of aspirin-like drugs used in a patient with Bartter's syndrome.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; I | 1979 |
[The effect of aldosterone antagonists in juvenile heart surgery].
Topics: Adolescent; Cardiopulmonary Bypass; Child; Child, Preschool; Drug Administration Schedule; Heart Def | 1979 |
[Experiences with aldactone in pediatric cardiology (author's transl)].
Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Heart Failure; Humans; Hyperaldosteronism | 1979 |
[Physiopathological study of low renin essential hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin; | 1977 |
Idiopathic edema: pathogenesis, clinical features, and treatment.
Topics: Adrenalectomy; Body Weight; Capillaries; Capillary Permeability; Edema; Female; Humans; Hyperaldoste | 1978 |
Muscle electrolytes and fluid compartments in six children with Bartter's syndrome.
Topics: Bartter Syndrome; Child; Child, Preschool; Chlorides; Female; Humans; Hyperaldosteronism; Male; Musc | 1978 |
Pharmacologic studies in Bartter's syndrome: opposite effects of treatment with antikaliuretic and antiprostaglandin drugs. Part I.
Topics: Adult; Amiloride; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potas | 1978 |
[Bartter's syndrome, with limited response to adrenalectomy].
Topics: Adrenalectomy; Adult; Bartter Syndrome; Female; Humans; Hyperaldosteronism; Hypokalemia; Juxtaglomer | 1978 |
Interference of spironolactone therapy with adrenal steroid metabolism in secondary hyperaldosteronism.
Topics: Adrenal Cortex Hormones; Adult; Humans; Hyperaldosteronism; Male; Spironolactone; Water-Electrolyte | 1978 |
The treatment of low-renin ("primary") hyperaldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Amiloride; Blood Pressure; Dexamethasone; Female; | 1978 |
Effect of spironolactone on urinary excretion of immunoreactive prostaglandin E in essential hypertension and primary aldosteronism.
Topics: Adult; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Kidney; Kinins; Male; Middle A | 1978 |
[Bartter's syndrome--studies on a patient with evidence for excessive prostaglandin synthesis (author's transl)].
Topics: Bartter Syndrome; Humans; Hyperaldosteronism; Indomethacin; Male; Middle Aged; Propranolol; Prostagl | 1978 |
[Bartter's syndrome. Current prospects of nosographic classification and new therapeutic possibilities].
Topics: Aldosterone; Bartter Syndrome; Child; Electrolytes; Female; Humans; Hyperaldosteronism; Indomethacin | 1978 |
[Effect of pregnancy and long-term treatment with spirolactone on the clinical and laboratory picture of primary hyperaldosteronism].
Topics: Adult; Female; Humans; Hyperaldosteronism; Pregnancy; Pregnancy Complications; Spironolactone | 1978 |
Bartter's syndrome without hyperplasia of the juxtaglomerular apparatus, treated with indomethacin.
Topics: Adult; Bartter Syndrome; Diet, Sodium-Restricted; Drug Evaluation; Humans; Hyperaldosteronism; Hyper | 1978 |
Adrenal scintigraphy in low renin essential hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Blood Pressure; Dexamethasone; Female; Hum | 1978 |
Hypophosphatemia and hyperparathyroidism in a case of Bartter's syndrome.
Topics: Adolescent; Alkalosis; Bartter Syndrome; Humans; Hyperaldosteronism; Hyperparathyroidism; Hypokalemi | 1978 |
Asymptomatic Bartter's syndrome.
Topics: Angiotensin II; Bartter Syndrome; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypokalemia | 1978 |
[Spirolactones and potassium-sparing diuretics].
Topics: Amiloride; Edema; Humans; Hyperaldosteronism; Hypertension; Pyrazines; Spironolactone; Triamterene | 1978 |
[Clinical experience in the use of Osyrol 100 and Osyrol for injection (author's transl)].
Topics: Administration, Oral; Aged; Blood Pressure; Body Weight; Canrenoic Acid; Female; Heart Failure; Huma | 1975 |
[Primary and idiopathic hyperaldosteronism. Course 1 year after operation. Apropos of 28 cases].
Topics: Adrenal Cortex Neoplasms; Biopsy; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Male; Mi | 1976 |
Effect of spironolactone on urinary kallikrein excretion in patients with essential hypertension and in primary aldosteronism.
Topics: Adult; Animals; Biological Assay; Dogs; Female; Fluorometry; Humans; Hyperaldosteronism; Hypertensio | 1977 |
Volume-pressure relationships during development of mineralocorticoid hypertension in man.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Insufficiency; Blood Pressure; Blood Volume; Electrolytes; | 1977 |
Diagnosis, localization, and treatment of primary aldosteronism.
Topics: Aldosterone; Antihypertensive Agents; Catheterization; Diagnosis, Differential; Humans; Hyperaldoste | 1977 |
[The renin-angiotensin-aldosterone system in hypertensive patients. II. Diagnosis of primary hyperaldosteronism].
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Aldosterone; Blo | 1977 |
Spironolactone-induced inhibition of aldosterone biosynthesis in primary aldosteronism: morphological and functional studies.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Aldosterone; Humans; Hyperaldosteronism; | 1977 |
[Use of a new water-soluble aldosterone-antagonist in surgery. Early clinical results].
Topics: Adult; Aged; Biliary Tract Diseases; Female; Gastrointestinal Diseases; Gastrointestinal Neoplasms; | 1976 |
Bartter's syndrome with hyperplasia of renomedullary cells: successful treatment with indomethacin.
Topics: Adult; Bartter Syndrome; Body Weight; Dose-Response Relationship, Drug; Humans; Hyperaldosteronism; | 1976 |
[Aldosteronism].
Topics: Diuretics; Humans; Hyperaldosteronism; Nephrotic Syndrome; Renal Artery Obstruction; Spironolactone | 1976 |
[Rectal electrical potential difference and plasma aldosterone in hyperaldosteronism and low-, normal- and high-renin hypertension].
Topics: Action Potentials; Adult; Aged; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Male; | 1976 |
[Edematous hepatitis: a special form of acute virus hepatitis with secondary aldosteronism (author's transl)].
Topics: Adult; Aldosterone; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Edema; Female; | 1975 |
[Origin and treatment of the socalled "cast syndrome" following operations for scoliosis (author's transl)].
Topics: Adolescent; Adult; Body Constitution; Casts, Surgical; Child; Duodenum; Female; Gastrointestinal Dis | 1975 |
Two cases of pseudoaldosteronism (Liddle's syndrome) in siblings.
Topics: Adolescent; Blood Pressure; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperaldosteroni | 1975 |
Bartter's syndrome: clinical study of its treatment with salt loading and propranolol.
Topics: Bartter Syndrome; Child; Child, Preschool; Follow-Up Studies; Humans; Hyperaldosteronism; Infant; Ma | 1975 |
Bartter's syndrome. New insights into pathogenesis and treatment.
Topics: Adult; Aldosterone; Angiotensin II; Bartter Syndrome; Blood Volume; Female; Humans; Hyperaldosteroni | 1975 |
[Case of Bartter syndrome].
Topics: Bartter Syndrome; Child, Preschool; Humans; Hyperaldosteronism; Male; Parathyroid Hormone; Propranol | 1975 |
Spironolactone, a reassessment.
Topics: Diuresis; Drug Combinations; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokale | 1975 |
Diagnosis and therapy of primary hyperaldosteronism in general practice.
Topics: Antihypertensive Agents; Family Practice; Female; Germany, East; Humans; Hyperaldosteronism; Middle | 1975 |
[A contribution on diagnostic and therapy of myxoedema coma (author's transl)].
Topics: Aged; Coma; Female; Humans; Hyperaldosteronism; Myxedema; Remission, Spontaneous; Spironolactone; Tr | 1975 |
[A question of logic].
Topics: Diazoxide; Furosemide; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Male; Middle Aged; | 1976 |
[Diagnosis and treatment of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hyperkalem | 1992 |
Twenty-four year spironolactone therapy in an aged patient with aldosterone-producing adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Aldosterone; Fe | 1992 |
[Aldosteronism and the related diseases].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Calcium Channel Blockers; Female; Humans; Hypera | 1992 |
Renin gene expression in the adrenal and kidney of patients with primary aldosteronism.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Carcinoma, Renal Cell; Gene Ex | 1992 |
Verapamil and nifedipine in combination for the treatment of hypertrophy heart disease.
Topics: Adrenal Gland Diseases; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; | 1991 |
A neonate with idiopathic hyperaldosteronism.
Topics: Aldosterone; Calcium; Gastrointestinal Diseases; Humans; Hyperaldosteronism; Hypokalemia; Infant, Ne | 1991 |
[2 cases of primary hyperaldosteronism].
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Combined Modality Therapy; Female; Humans; Hyperaldosteron | 1991 |
[Abnormal production of adrenal gland hormones--special reference to mineralocorticoids].
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Aldosterone; Calcium Channel Blockers; Dexameth | 1991 |
Pseudohyperaldosteronism from liquorice-containing laxatives.
Topics: Adult; Aged; Aldosterone; Cathartics; Drug Combinations; Female; Glycyrrhiza; Humans; Hyperaldostero | 1990 |
Time-related changes in plasma adrenal steroids during treatment with spironolactone in primary aldosteronism.
Topics: Adenoma; Administration, Oral; Adrenal Gland Neoplasms; Adult; Aldosterone; Corticosterone; Desoxyco | 1990 |
Bartter's syndrome--treatment with potassium, spironolactone and ACE-inhibitor.
Topics: Adult; Bartter Syndrome; Captopril; Drug Therapy, Combination; Female; Humans; Hyperaldosteronism; P | 1989 |
Plasma aldosterone level in a female case of pseudohyperaldosteronism (Liddle's syndrome).
Topics: Adult; Aldosterone; Blood Pressure; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperald | 1989 |
Disappearance of spironolactone-induced gynaecomastia during treatment with potassium canrenoate.
Topics: Canrenoic Acid; Gynecomastia; Humans; Hyperaldosteronism; Male; Middle Aged; Pregnadienes; Spironola | 1985 |
Plasma levels of atrial natriuretic peptide in primary aldosteronism and essential hypertension.
Topics: Adult; Atrial Natriuretic Factor; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Age | 1986 |
Role of atrial natriuretic peptide in mineralocorticoid escape phenomenon in patients with primary aldosteronism.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Desoxycorticosterone; Humans; Hydroco | 1987 |
Plasma atrial natriuretic peptide (ANP) in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aldosterone; Atrial Natriuretic Factor; Fem | 1988 |
Ultrastructural studies of adrenal adenoma causing primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Cell Nucleus; Endoplasmic Reticulum; Female; Humans; Hyper | 1985 |
Glucocorticoid-suppressible hyperaldosteronism. Ultrastructural observation of a case.
Topics: Adrenal Cortex; Aldosterone; Dexamethasone; Endoplasmic Reticulum; Female; Humans; Hyperaldosteronis | 1985 |
[Hyperaldosteronism and cerebrovascular disease; report of 4 cases].
Topics: Adult; Cerebrovascular Disorders; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin | 1988 |
[Results of the surgical treatment of Conn's adenomas].
Topics: Adenoma; Adrenal Gland Neoplasms; Female; Humans; Hyperaldosteronism; Hypertension; Male; Retrospect | 1987 |
Long-term results of surgical and conservative treatment of patients with primary aldosteronism.
Topics: Adrenalectomy; Blood Pressure; Humans; Hyperaldosteronism; Spironolactone; Time Factors | 1987 |
Pre-operative evaluation of the prognosis of hypertension in primary aldosteronism owing to adenoma.
Topics: Adenoma; Adult; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pituitary Neopl | 1987 |
[Therapy of primary aldosteronism].
Topics: Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenalectomy; Carcinoma; Diagnosis, Dif | 1986 |
Amiloride-sensitive salt and fluid absorption in small intestine of sodium-depleted rats.
Topics: Adrenalectomy; Amiloride; Animals; Body Water; Colon; Diet, Sodium-Restricted; Electric Conductivity | 1985 |
Hypertension with aldosterone excess and low plasma-renin: preoperative distinction between patients with and without adrenocortical tumour.
Topics: Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Age Fac | 1970 |
Fine structure and morphogenesis of spironolactone bodies in the zona glomerulosa of the human adrenal cortex.
Topics: Adrenal Glands; Adrenalectomy; Adult; Cytoplasmic Granules; Endoplasmic Reticulum; Female; Golgi App | 1973 |
Functional black adenoma of the adrenal cortex. A rare cause of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Dexamethasone; Female; Histocytochemistry; Humans; Hyperald | 1974 |
Sodium and the renin-angiotensin system in essential hypertension and mineralocorticoid excess.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diagnosis, Differential; Fe | 1974 |
Hyperaldosteronism and migraine.
Topics: Humans; Hyperaldosteronism; Migraine Disorders; Spironolactone | 1968 |
Clinical investigation of the effects of adrenal corticosteroid excess on the colon.
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adult; Aldosterone; Colon; C | 1969 |
[Myocardial hyperexcitability in decompensated cardiopathies. Effect of spironolactone].
Topics: Cardiac Complexes, Premature; Dehydration; Digitalis Glycosides; Diuresis; Diuretics; Heart Failure; | 1969 |
Measurement of rectal electrical potential difference as an instant screening-test for hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Ascites; Electrodes; Electrodiagnosis; Feces; Fludrocortisone; Hum | 1970 |
The influence of a heparin-like compound on hypertension, electrolytes and aldosterone in man.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Blood Pressure; Female; Glycosaminoglycans; | 1966 |
Proceedings: On the role of diuretic-and spironolactone-induced hyperaldosteronism on electrolyte excretion in man.
Topics: Aldosterone; Diuretics; Furosemide; Humans; Hyperaldosteronism; Potassium; Sodium; Spironolactone; T | 1974 |
Inhibition of aldosterone production in diuretic-induced hyperaldosteronism by aldosterone antagonist canrenone in man.
Topics: Aldosterone; Butanes; Depression, Chemical; Diuresis; Hematocrit; Humans; Hydrochlorothiazide; Hyper | 1974 |
The effect of saluretics and spironolactone on aldosterone production and electrolyte excretion in man.
Topics: Adult; Aldosterone; Butanes; Diuresis; Female; Furosemide; Humans; Hydrochlorothiazide; Hyperaldoste | 1974 |
[Bartter syndrome. Vascular angiotensin II resistance with juxtaglomerular cellular hyperplasia and hyperaldosteronism].
Topics: Adult; Angiotensin II; Humans; Hyperaldosteronism; Hyperplasia; Hypokalemia; Kidney Diseases; Potass | 1965 |
Normotensive secondary hyperaldosteronism.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Child, Preschool; Diet Therapy; Dwarfism; Female | 1966 |
Hypokalaemic alkalosis and hyperplasia of the juxtaglomerular apparatus without hypertension or oedema.
Topics: Adolescent; Alkalosis; Angiotensin II; Blood Pressure; Extracellular Space; Humans; Hyperaldosteroni | 1967 |
Hyperplasia of the juxtaglomerular complex with secondary aldosteronism without hypertension (Bartter's syndrome).
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Ammonium Chloride; Angiotensin II; Bicarb | 1968 |
Activation of aldosterone secretion in primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Glucocorticoids; | 1969 |
[Differential diagnosis of the Bartter syndrome].
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Biopsy; Chymosin; Diagnosis, Differential; Female; Hu | 1968 |
Medical grand rounds from the University of Alabama Medical Center.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertens | 1969 |
Pathogenesis of Bartter's syndrome.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Albumins; Aldosterone; Alkalosis; Angiotensin I | 1969 |
Bartter's syndrome. A report of four cases, including three in one sibship, with comparative histologic evaluation of the juxtaglomerular apparatuses and glomeruli.
Topics: Alkalosis; Angiotensin II; Blood Pressure; Carbon Dioxide; Cerebrospinal Fluid Proteins; Electrolyte | 1970 |
An unusual type of hypokalaemic alkalosis with a disturbance of renin and aldosterone.
Topics: Adolescent; Adrenal Cortex Hormones; Albumins; Aldosterone; Alkalosis; Angiotensin II; Creatinine; D | 1970 |
Case studies of siblings with juxtaglomerular hyperplasia and secondary aldosteronism associated with severe azotemia and renal rickets--Bartter's syndrome or disease?
Topics: Aldosterone; Alkalosis; Angiotensin II; Bone Diseases; Child; Child, Preschool; Humans; Hyperaldoste | 1970 |
Neurodegenerative disorders and hyperaldosteronism.
Topics: Adolescent; Aldosterone; Angiotensin II; Birth Weight; Blood Pressure; Body Weight; Bundle-Branch Bl | 1971 |
[The renin-angiotensin-aldosterone system. Disorders and methods of clinical research].
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Dexamethasone; Electrol | 1970 |
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pr | 1972 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cor | 1972 |
[Physiopathologic bases of diagnosis and treatment of primary hyperaldosteronism].
Topics: Aged; Angiotensin II; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Potassium; Renin; Sodiu | 1970 |
A kindred with familial glucocorticoid suppressible aldosteronism.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Binding, Competitive; Child; Dexam | 1973 |
[Plasma aldosterone levels in primary aldosteronism. 1. Renin-angiotensin system and aldosterone].
Topics: Aldosterone; Angiotensin II; Enzyme Activation; Furosemide; Humans; Hydrochlorothiazide; Hyperaldost | 1973 |
Six year follow-up of a child with Bartter syndrome.
Topics: Aldosterone; Alkalosis; Angiotensin II; Biopsy; Blood Pressure; Child, Preschool; Diet Therapy; Fema | 1973 |
Some observations on the pathogenesis of Bartter's syndrome.
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Blood Volume; Drug Therapy, Combination; Humans; Hype | 1973 |
Control of plasma aldosterone in primary aldosteronism: distinction between adenoma and hyperplasia.
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Circadian Rhythm; Dexamethasone; Diet; Female; Hu | 1973 |
Spironolactone inclusions in an aldosteronoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Cytoplasmic Granules; Humans; Hyper | 1974 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extr | 1973 |
Renin-angiotensin-aldosterone system of a woman with Bartter's syndrome: Juxtaglomerular cell hyperplasia without hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hyp | 1974 |
Reduced aldosterone secretion during spironolactone treatment in primary aldosteronism: report of a case.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Choleste | 1974 |
The role of mineralocorticoids in the pathogenesis of hypokalemic periodic paralysis.
Topics: Adult; Aldosterone; Angiotensin II; Desoxycorticosterone; Humans; Hydrocortisone; Hyperaldosteronism | 1974 |
Pseudohypoaldosteronism: persistence of hyperaldosteronism and evidence for renal tubular and intestinal responsiveness to endogenous aldosterone.
Topics: Aldosterone; Angiotensin II; Child; Colon; Creatinine; Feces; Humans; Hydrocortisone; Hyperaldostero | 1974 |
[A description of a case of Conn's syndrome (author's transl)].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aortography; Female; Humans; | 1974 |
Idiopathic edema.
Topics: Adult; Age Factors; Aldosterone; Edema; Female; Heart Failure; Humans; Hydrochlorothiazide; Hydrosta | 1974 |
Urinary kallikrein excretion in hypertensive man. Relationships to sodium intake and sodium-retaining steroids.
Topics: Adult; Aldosterone; Blood Pressure; Diet; Diet, Sodium-Restricted; Fludrocortisone; Humans; Hyperald | 1974 |
[Importance of spironolactone in the diuretic treatment].
Topics: Diuresis; Humans; Hyperaldosteronism; Spironolactone | 1974 |
[Barrter's syndrome].
Topics: Anorexia Nervosa; Bartter Syndrome; Humans; Hyperaldosteronism; Prognosis; Spironolactone; Triamtere | 1974 |
Diuretics.
Topics: Benzothiadiazines; Blood; Chlorides; Diuretics; Diuretics, Osmotic; Edema; Ethacrynic Acid; Heart Di | 1974 |
[Variations in renin and aldosterone activity in a typical case of Barter syndrome. Influence of anti-aldosterones and sodium intake].
Topics: Adult; Aldosterone; Bartter Syndrome; Biological Transport, Active; Biopsy; Humans; Hyperaldosteroni | 1974 |
Management of potassium problems during long-term diuretic therapy.
Topics: Aldosterone; Diet; Diuretics; Extracellular Space; Homeostasis; Humans; Hydrogen-Ion Concentration; | 1974 |
Antihypertensive effect of spironolactone in essential, renal and mineralocorticoid hypertension.
Topics: Adult; Aldosterone; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Di | 1973 |
Faecal sodium-potassium ratio and aldosteronism in experimental hypertension in the rat.
Topics: Animals; Chronic Disease; Feces; Female; Hyperaldosteronism; Hypertension; Kidney; Nephrectomy; Pota | 1972 |
[Treatment of essential arterial hypertension with spironolactone: its value in the detection of primary hyperaldosteronism and prediction of its efficacy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Age Factors; Aldosterone; Diet Therapy; Humans; Hyperald | 1972 |
[Pathogenesis of essential hypertension with suppressed plasma renin activity].
Topics: Adult; Blood Pressure; Diet, Sodium-Restricted; Diuresis; Female; Furosemide; Humans; Hyperaldostero | 1972 |
Studies on essential hypertension with suppressed plasma renin activity: sodium excretion pattern on salt restriction and effects of spironolactone on blood pressure and plasma renin activity.
Topics: Adult; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hyperaldost | 1972 |
The diagnostic and therapeutic value of spironolactone in patients with systemic hypertension.
Topics: Acid-Base Equilibrium; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood Press | 1973 |
Role of the adrenal cortex in hypertension.
Topics: Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Humans; Hyperaldosteronism; Hypertensio | 1973 |
[Pathogenesis of hypertension in primary aldosteronism].
Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Female; Heart Rate; Humans; Hyperaldosteronism; | 1973 |
[Primary hyperaldosteronism with malignant hypertension].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Blood Pressure Determination; Female; Humans | 1973 |
[Bartter's syndrome in adults. Case report with light- and electron-microscopic findings].
Topics: Adult; Alkalosis; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Hypoten | 1973 |
Volume-dependent essential and steroid hypertension.
Topics: Adult; Aged; Aldosterone; Diet, Sodium-Restricted; Female; Follow-Up Studies; Humans; Hydrochlorothi | 1973 |
Amiloride in primary hyperaldosteronism with chronic peptic ulceration.
Topics: Aged; Amiloride; Bicarbonates; Blood Pressure; Body Water; Chlorides; Chronic Disease; Diuretics; Fe | 1973 |
[Therapy of secondary hyperaldosteronism].
Topics: Aminoglutethimide; Butanones; Heparin; Humans; Hyperaldosteronism; Metyrapone; Mineralocorticoid Rec | 1973 |
Experience with primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Female; Follow-Up Studies; Huma | 1973 |
Spironolactone as a nonspecific treatment for primary aldosteronism.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Creatini | 1973 |
[Treatment of essential arterial hypertension with spironolactone: its value for the screening of primary hyperaldosteronism and prediction of its efficacy].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Probability; Spironolactone | 1973 |
[The role of anti-aldosterones in the treatment of arterial hypertension].
Topics: Aldosterone; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Potas | 1973 |
[Research on the pathogenesis of hypertension in primary hyperaldosteronism].
Topics: Adrenal Gland Diseases; Animals; Hemodynamics; Hyperaldosteronism; Hyperplasia; Hypertension; Spiron | 1973 |
Studies on the mechanism of aldosterone-induced hypertension in man.
Topics: Adult; Blood Pressure; Cardiac Output; Chromium Radioisotopes; Extracellular Space; Female; Heart Ra | 1973 |
[Primary aldosteronism (clinical study and outcome of 8 cases)].
Topics: Adult; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Spironolactone | 1973 |
Pathogenesis of essential hypertension with a suppressed plasma renin activity.
Topics: Humans; Hyperaldosteronism; Hypertension; Renin; Spironolactone | 1973 |
Urologic considerations in Bartter's syndrome.
Topics: Adolescent; Adult; Biopsy; Carpal Bones; Female; Foot; Humans; Hydronephrosis; Hyperaldosteronism; H | 1974 |
[The value of studying essential arterial hypertension with isotopic methods. Their application in arterial hypertension with low renin level].
Topics: Adult; Body Water; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Plasma Volum | 1974 |
[New aspects of the use of spironolactone and its association with thiabutazide (per os and in injections) in the treatment of grave cardiac insufficiency].
Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Benzothiadiazines; Diabetes Complications; D | 1974 |
[Sodium-potassium ratio and electrical potential of colon in the screening of hyperaldosteronism (author's transl)].
Topics: Colon; Feces; Humans; Hyperaldosteronism; Hypertension; Membrane Potentials; Potassium; Sodium; Spir | 1974 |
[Aldosteronism in liver diseases].
Topics: Acute Disease; Aldosterone; Chronic Disease; Humans; Hyperaldosteronism; Liver Diseases; Spironolact | 1974 |
[Aldosteronism in cardiopulmonary diseases].
Topics: Aldosterone; Edema; Humans; Hyperaldosteronism; Metabolic Clearance Rate; Pulmonary Heart Disease; S | 1974 |
[Primary hyperaldosteronism].
Topics: Humans; Hyperaldosteronism; Spironolactone | 1970 |
[Antikaliuretic agents].
Topics: Adult; Aged; Aldosterone; Chemistry; Diuretics; Female; History, 20th Century; Humans; Hyperaldoster | 1971 |
Aldosterone excess and adrenal carcinoma.
Topics: Adrenal Gland Neoplasms; Aged; Aldosterone; Carcinoma; Humans; Hyperaldosteronism; Spironolactone | 1972 |
Hyporeninemic hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Blood Urea Nitrogen; Catecholamines; Diet, Sod | 1972 |
[Renin and aldosterone regulation in idiopathic edemas].
Topics: Adult; Aldosterone; Edema; Female; Humans; Hyperaldosteronism; Middle Aged; Renin; Spironolactone; S | 1972 |
Primary aldosteronism. Review of diagnostic tests and 15 cases.
Topics: Academic Dissertations as Topic; Adult; Aged; Aldosterone; Diagnosis, Differential; Electrolytes; Ev | 1972 |
Myopathy in association with primary hyperaldosteronism.
Topics: Electromyography; Humans; Hyperaldosteronism; Male; Middle Aged; Muscular Diseases; Potassium; Sodiu | 1972 |
Hyperaldosteronism from adrenal carcinoma.
Topics: Adrenal Gland Neoplasms; Adult; Carcinoma; Humans; Hyperaldosteronism; Male; Spironolactone | 1972 |
[Electrocardiographic observations in secondary aldosteronism].
Topics: Aged; Aldosterone; Body Weight; Digitalis Glycosides; Diuresis; Electrocardiography; Female; Heart F | 1972 |
Clinical study of verospirone and spironolactone.
Topics: Adult; Aged; Diuretics; Female; Heart Failure; Humans; Hyperaldosteronism; Liver Cirrhosis; Male; Mi | 1972 |
[Modification of ionic balance by an injectable antialdosterone drug in resuscitation].
Topics: Cell Membrane Permeability; Diuresis; Female; Humans; Hyperaldosteronism; Injections, Intravenous; M | 1972 |
Erythrocyte function and aldosterone.
Topics: Adrenalectomy; Aldosterone; Animals; Elasticity; Erythrocytes; Hematocrit; Heparin; Humans; Hyperald | 1971 |
[Primary aldosteronism].
Topics: Adrenal Gland Neoplasms; Female; Humans; Hyperaldosteronism; Middle Aged; Prognosis; Renin; Spironol | 1971 |
[Problems in Bartter's syndrome].
Topics: Alkalosis; Biopsy; Child, Preschool; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; | 1971 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |
Chronic hypokalaemia with growth retardation, normotensive hyperrenin-hyperaldosteronism ("Bartter's syndrome"), and hypercalciuria. Report of two cases with emphasis on natural history and on catch-up growth during treatment.
Topics: Alkalosis; Calcium; Child; Chronic Disease; Female; Growth Disorders; Humans; Hyperaldosteronism; Hy | 1971 |
[Primary hyperaldosteronism: differentiation between adenoma and primary hyperplasia of the adrenal glands and operative indications].
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Dexamethasone; Diagnosis, Dif | 1971 |
Aldosterone antagonists and triamterene.
Topics: Aldosterone; Humans; Hyperaldosteronism; Natriuresis; Potassium; Spironolactone; Triamterene | 1966 |
[Treatment of secondary hyperaldosteronism].
Topics: Adrenalectomy; Aldosterone; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Diuretics; Humans | 1969 |
Spironolactone in hyperaldosteronism.
Topics: Female; Humans; Hyperaldosteronism; Middle Aged; Spironolactone | 1969 |
Hypertension and hyperaldosteronism with low plasma renin concentration: analysis of a series of eighty-two patients.
Topics: Adrenal Glands; Aldosterone; Body Weight; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; P | 1969 |
Stenosis of the inferior vena cava with secondary hyperaldosteronism.
Topics: Angiography; Body Weight; Constriction; Diuresis; Diuretics; Edema; Humans; Hyperaldosteronism; Infa | 1969 |
Suppressed plasma renin activity in in hypertensive patients--its evaluation for the diagnosis of primary aldosteronism.
Topics: Aldosterone; Cushing Syndrome; Diet, Sodium-Restricted; Glomerulonephritis; Humans; Hydrochlorothiaz | 1969 |
[Induced aldosteronism in hydropic heart insufficiency].
Topics: Acid-Base Equilibrium; Adult; Aged; Aldosterone; Body Weight; Carbon Isotopes; Cardiac Glycosides; E | 1969 |
[The patient with edema].
Topics: Adolescent; Adult; Dietary Proteins; Diuretics; Edema; Electrocardiography; Female; Heart Failure; H | 1969 |
Increased plasma renin activity, secondary aldosteronism, and hypertension.
Topics: Child; Enuresis; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Function Tests; Potassium; | 1970 |
Serum magnesium in children with cirrhosis.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Hyperaldosteronism; Infant; Liver Cirrhosis; Ma | 1970 |
[Primary aldosteronism and its surgical treatment].
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Child; Female; Huma | 1970 |
The syndrome of primary aldosteronism.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Blood U | 1970 |
Drug-induced secondary hyperaldosteronism in patients with pulmonary tuberculosis.
Topics: Adult; Aldosterone; Female; Gentamicins; Humans; Hyperaldosteronism; Hypokalemia; Magnesium; Male; M | 1970 |
[Spironolactone test for the diagnosis of primary hyperaldosteronism].
Topics: Adult; Female; Humans; Hyperaldosteronism; Methods; Spironolactone | 1970 |
[Effect of long-term administration of spironolactone in massive dosage on the postoperative plasma renin activity in primary aldosteronism].
Topics: Adolescent; Adult; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Potassium; Renin; Sodium; | 1970 |
[1st results of the use of Soludactone in the treatment of certain forms of cerebral edema].
Topics: Adolescent; Adult; Aged; Aldosterone; Brain Edema; Female; Humans; Hyperaldosteronism; Male; Middle | 1970 |
[Cerebral edema and hyperaldosteronism].
Topics: Brain Edema; Brain Injuries; Humans; Hyperaldosteronism; Potassium; Sodium; Spironolactone | 1970 |
Management of aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aminoglutethimide; Humans; Hyperaldosteronism; Min | 1970 |
[Spironolactone preparations].
Topics: Administration, Oral; Edema; Humans; Hyperaldosteronism; Spironolactone; Water-Electrolyte Balance | 1970 |
Effect of spironolactone in hypertensive patients.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Antihypertensive Agents; Blood Urea Nitrogen; Fema | 1970 |
Effects of aldosterone and cortisol on human erythrocyte Na efflux.
Topics: Aldosterone; Biological Transport, Active; Cushing Syndrome; Erythrocytes; Humans; Hydrocortisone; H | 1971 |
Erythrocyte Na flux in a patient with Bartter's syndrome.
Topics: Aldosterone; Alkalosis; Ammonium Chloride; Biological Transport; Biological Transport, Active; Cell | 1971 |
[The spironolactone test at high dosage in the study of arterial hypertension with hyperaldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperte | 1971 |
[Endocrinologic and circulatory findings in a case of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Female; Hemodynamics; Humans; Hyperaldosteronism; Hyp | 1971 |
Urinary citrate excretion in primary aldosteronism.
Topics: Addison Disease; Adult; Aldosterone; Carbon Dioxide; Citrates; Desoxycorticosterone; Dexamethasone; | 1967 |
[Periodic paralyses].
Topics: Adrenal Insufficiency; Adult; Humans; Hyperaldosteronism; Hyperthyroidism; Hypokalemia; Male; Muscle | 1967 |
[Hypokalemic ileus and aldosteronism].
Topics: Adolescent; Aged; Humans; Hyperaldosteronism; Hypokalemia; Iatrogenic Disease; Injections, Intraveno | 1967 |
[Anti-aldosterone therapy in cirrhosis of the liver with ascites].
Topics: Ascites; Humans; Hyperaldosteronism; Liver Cirrhosis; Spironolactone | 1967 |
[Spironolactone test in the diagnosis of primary and secondary hyperaldosteronism in renal ischemia].
Topics: Adolescent; Adult; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension, Renal; Male; Midd | 1967 |
[Studies on the effect of the aldosterone-antagonist aldadeine-potassium on secondary aldosteronism after surgery with the heart-lung machine].
Topics: Acid-Base Equilibrium; Adult; Cardiac Surgical Procedures; Diuresis; Electrolytes; Erythrocytes; Hea | 1967 |
[The use of aldactone A in primary and secondary aldosteronism].
Topics: Adolescent; Adult; Biopsy; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension | 1968 |
Unilateral adrenalectomy for aldosteronomas localized preoperatively by differential adrenal vein catheterization.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiography; Ao | 1968 |
Primary aldosteronism.
Topics: Aldosterone; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor An | 1968 |
Aldosteronism in hypertension. The spironolactone response test.
Topics: Adrenalectomy; Aldosterone; Blood Pressure; Body Weight; Diagnosis, Differential; Electrolytes; Huma | 1968 |
[Renin studies in idiopathic edemas with secondary hyperaldosteronism].
Topics: Adolescent; Adult; Aldosterone; Dextrans; Edema; Female; Humans; Hyperaldosteronism; Infusions, Pare | 1968 |
[Kidney artery stenosis, renal hypertension and secondary hyperaldosteronism in an 8-year-old boy. (Stunted growth through potassium deficiency)].
Topics: Adrenal Glands; Aldosterone; Child; Dwarfism; Humans; Hyperaldosteronism; Hypertension, Renal; Hypok | 1968 |
[Hyperaldosteronism and the use of aldactone in cardiac insufficiency].
Topics: Adult; Aldosterone; Blood Flow Velocity; Blood Volume; Cardiac Output; Diuresis; Female; Heart Failu | 1968 |
Test for pathologic secretion of aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Diet; Humans; Hyperaldosteronism; Hyperplasia; Hypert | 1968 |
Potassium losing pyelonephritis. Response to spironolactone.
Topics: Aged; Diet Therapy; Humans; Hyperaldosteronism; Hypokalemia; Male; Peptic Ulcer; Potassium; Potassiu | 1969 |
[Primary hyperaldosteronism. Description of a clinical case].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adult; Alkalosis; Electrolytes; | 1969 |
Estimation of plasma potassium, renin and aldosterone in the diagnosis of primary hyperaldosteronism; the role of spironolactone in the treatment of this syndrome.
Topics: Aldosterone; Humans; Hyperaldosteronism; Potassium; Renin; Serologic Tests; Spironolactone | 1969 |
Aldosteronism and spironolactone.
Topics: Aldosterone; Humans; Hyperaldosteronism; Renin; Spironolactone | 1969 |
Aldosterone and spironolactone.
Topics: Aldosterone; Humans; Hyperaldosteronism; Renin; Spironolactone | 1969 |
[Effect of spironolactone on the excretion of sodium and potassium in the saliva in secondary hyperaldosteronism].
Topics: Heart Failure; Humans; Hyperaldosteronism; Liver Cirrhosis; Potassium; Saliva; Sodium; Spironolacton | 1969 |
[Diuretics in cirrhosis. Accidents. Indications].
Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic | 1969 |
[Inhibitions of steroid biosynthesis in the adrenal gland by aminogluthetimide (Elipten CIBA) and its practical significance].
Topics: 17-Ketosteroids; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Cushing Synd | 1969 |
Non-tumorous "primary" aldosteronism: II. Type not relieved by glucocorticoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Blood | 1969 |
Non-tumorous "primary" aldosteronism. I. Type relieved by glucocorticoid (glucocorticoid-remediable aldosteronism).
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adult; Aldosterone; Androgens | 1969 |
[Clinical use of concurrent antagonists of aldosterone in patients with cardiac insufficiency].
Topics: Adult; Arrhythmias, Cardiac; Caproates; Cardiac Glycosides; Diuretics; Drug Tolerance; Ethisterone; | 1969 |
Management of primary and secondary hyperaldosteronism.
Topics: Diuretics; Humans; Hyperaldosteronism; Spironolactone | 1969 |
Plasma renin activity in the diagnosis of primary aldosteronism: failure to distinguish primary aldosteronism from essential hypertension.
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Animals; Biological Assay; Blood Urea Nitrogen; Chlorot | 1969 |
[Therapeutically induced aldosteronism in hydropic cardiac insufficiency].
Topics: Aldosterone; Carbon Isotopes; Cardiac Glycosides; Diuretics; Heart Failure; Humans; Hyperaldosteroni | 1969 |
Hyperaldosteronism.
Topics: Humans; Hyperaldosteronism; Spironolactone | 1969 |
The effect of adrenal steroids on stool composition, as revealed by in vivo dialysis of faeces.
Topics: Adult; Aldosterone; Depression, Chemical; Dialysis; Feces; Female; Fludrocortisone; Humans; Hydrocor | 1969 |
Plasma concentration of renin in a patient with Conn's syndrome with fibrinoid lesions of the renal arterioles: the effect of treatment with spironolactone.
Topics: Adrenal Gland Neoplasms; Adult; Aminohippuric Acids; Blood; Blood Volume; Creatine; Extracellular Sp | 1965 |
Conn's syndrome due to adrenal hyperplasia with hypertrophy of zona glomerulosa, relieved by unilateral adrenalectomy.
Topics: Adrenal Gland Diseases; Adrenalectomy; Adult; Alkalosis; Humans; Hydrocortisone; Hyperaldosteronism; | 1965 |
[Secondary aldosteronism following surgery using the heart-lung machine and its regulation with Aldactone].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aldosterone; Alkalosis; Cardiac Surgical Procedures; Child | 1965 |
[Secondary hyperaldosteronism of ascitogenic cirrhosis. Therapeutic results].
Topics: Humans; Hyperaldosteronism; Liver Cirrhosis; Prednisone; Spironolactone | 1963 |
[Modification of sweat electrolytes by spirolactones in secondary hyperaldosteronism].
Topics: Addison Disease; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Liver Cirrhosis; Potassium; So | 1965 |
[Secondary hyperaldosteronism as a secondary disease in intractable cardiac decompensation].
Topics: Adult; Cardiac Surgical Procedures; Digitalis Glycosides; Diuresis; Electrocardiography; Female; Hea | 1965 |
Conn's syndrome. A detailed study on corticoid metabolites in the urine in two operated cases.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adult; Blood Pressure Determination; Chro | 1966 |
Surgical aspects of hypertension.
Topics: Adrenalectomy; Endarterectomy; Humans; Hyperaldosteronism; Hypertension; Renal Artery Obstruction; R | 1966 |
Primary aldosteronism due to adrenocortical adenoma (Conn's syndrome).
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Female; Humans; Hyperaldosteronism; Hypokalemia; Paralysis; | 1966 |
[Diuresis therapy in hyperaldosteronism].
Topics: Adult; Aged; Aorta; Edema; Female; Heart Failure; Humans; Hyperaldosteronism; Liver Cirrhosis; Male; | 1966 |