spironolactone has been researched along with Hidradenitis Suppurativa in 10 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Hidradenitis Suppurativa: A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with spironolactone aims to attenuate androgen-mediated conditions including acne, hidradenitis suppurativa, female pattern hair loss and hirsutism." | 6.66 | Spironolactone in dermatology: uses in acne and beyond. ( Al-Niaimi, F; Ali, FR; Searle, TN, 2020) |
| "Spironolactone is an economical potassium-sparing diuretic with an anti-androgenic effect and a good safety profile." | 5.56 | Spironolactone in Dermatology: Uses in Acne, Hidradenitis Suppurativa, Female Pattern Baldness, and Hirsutism. ( Morgado-Carrasco, D; Vargas-Mora, P, 2020) |
| "Hormonal therapy is a potential treatment for hidradenitis suppurativa (HS)." | 5.51 | Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa. ( Golbari, NM; Kimball, AB; Porter, ML, 2019) |
| "Hormonal treatments in hidradenitis suppurativa: a systematic review." | 3.01 | Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review. ( Hsiao, JL; Jeong, C; Masson, R; Shi, VY; Shih, T, 2023) |
| "Spironolactone is a drug, similar in structure to aldosterone and acts as an aldosterone receptor antagonist with an anti-androgenic effect." | 2.82 | Spironolactone in dermatology. ( Aguilar Medina, DA; Cazarín, J; Magaña, M, 2022) |
| "Treatment with spironolactone aims to attenuate androgen-mediated conditions including acne, hidradenitis suppurativa, female pattern hair loss and hirsutism." | 2.66 | Spironolactone in dermatology: uses in acne and beyond. ( Al-Niaimi, F; Ali, FR; Searle, TN, 2020) |
| "Hidradenitis suppurativa/acne inversa is a disease with deep-seated chronic painful nodules, abscesses, and draining sinus tracts, which manifests on the apocrine gland-rich skin areas of the body." | 2.61 | Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data. ( Kyrgidis, A; Nikolakis, G; Zouboulis, CC, 2019) |
| "Hidradenitis suppurativa is a recurrent inflammatory skin condition characterized by abscesses and boils, predominantly in the groin, armpit, and buttocks areas." | 2.55 | Hormonal therapies for hidradenitis suppurativa: Review. ( Clark, AK; Quinonez, RL; Saric, S; Sivamani, RK, 2017) |
| "Spironolactone is an economical potassium-sparing diuretic with an anti-androgenic effect and a good safety profile." | 1.56 | Spironolactone in Dermatology: Uses in Acne, Hidradenitis Suppurativa, Female Pattern Baldness, and Hirsutism. ( Morgado-Carrasco, D; Vargas-Mora, P, 2020) |
| "Hormonal therapy is a potential treatment for hidradenitis suppurativa (HS)." | 1.51 | Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa. ( Golbari, NM; Kimball, AB; Porter, ML, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 6 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horissian, M | 1 |
| Maczuga, S | 1 |
| Barbieri, JS | 1 |
| Zaenglein, AL | 1 |
| Aguilar Medina, DA | 1 |
| Cazarín, J | 1 |
| Magaña, M | 1 |
| Masson, R | 1 |
| Shih, T | 1 |
| Jeong, C | 1 |
| Shi, VY | 1 |
| Hsiao, JL | 1 |
| Quinlan, C | 1 |
| Kirby, B | 1 |
| Hughes, R | 1 |
| Vargas-Mora, P | 1 |
| Morgado-Carrasco, D | 1 |
| Searle, TN | 1 |
| Al-Niaimi, F | 1 |
| Ali, FR | 1 |
| Clark, AK | 1 |
| Quinonez, RL | 1 |
| Saric, S | 1 |
| Sivamani, RK | 1 |
| Golbari, NM | 1 |
| Porter, ML | 1 |
| Kimball, AB | 1 |
| Nikolakis, G | 1 |
| Kyrgidis, A | 1 |
| Zouboulis, CC | 1 |
| Lee, A | 1 |
| Fischer, G | 1 |
5 reviews available for spironolactone and Hidradenitis Suppurativa
| Article | Year |
|---|---|
Spironolactone in dermatology.
Topics: Acne Vulgaris; Dermatology; Female; Hidradenitis Suppurativa; Hirsutism; Humans; Spironolactone | 2022 |
Hormonal Treatments in Hidradenitis Suppurativa: A Systematic Review.
Topics: Finasteride; Flutamide; Hidradenitis Suppurativa; Humans; Liraglutide; Metformin; Spironolactone | 2023 |
Spironolactone in dermatology: uses in acne and beyond.
Topics: Acne Vulgaris; Adult; Alopecia; Dermatology; Drug Monitoring; Female; Hidradenitis Suppurativa; Hirs | 2020 |
Hormonal therapies for hidradenitis suppurativa: Review.
Topics: 5-alpha Reductase Inhibitors; Contraceptives, Oral, Hormonal; Dutasteride; Female; Finasteride; Hidr | 2017 |
Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data.
Topics: Androgen Antagonists; Androgens; Cyproterone Acetate; Drug Therapy, Combination; Finasteride; Hidrad | 2019 |
5 other studies available for spironolactone and Hidradenitis Suppurativa
| Article | Year |
|---|---|
Trends in the prescribing pattern of spironolactone for acne and hidradenitis suppurativa in adolescents.
Topics: Acne Vulgaris; Adolescent; Hidradenitis Suppurativa; Humans; Spironolactone | 2022 |
Spironolactone therapy for hidradenitis suppurativa.
Topics: Adult; Aftercare; Androgen Antagonists; Female; Hidradenitis Suppurativa; Humans; Middle Aged; Retro | 2020 |
Spironolactone in Dermatology: Uses in Acne, Hidradenitis Suppurativa, Female Pattern Baldness, and Hirsutism.
Topics: Acne Vulgaris; Alopecia; Dermatology; Female; Hidradenitis Suppurativa; Hirsutism; Humans; Spironola | 2020 |
Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa.
Topics: Adult; Androgen Antagonists; Female; Hidradenitis Suppurativa; Humans; Retrospective Studies; Spiron | 2019 |
A case series of 20 women with hidradenitis suppurativa treated with spironolactone.
Topics: Adolescent; Adult; Androgen Antagonists; Female; Hidradenitis Suppurativa; Humans; Middle Aged; Retr | 2015 |