spironolactone has been researched along with Heart Valve Diseases in 18 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (72.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Franchini, A | 1 |
| Borgarelli, M | 2 |
| Abbott, JA | 1 |
| Menciotti, G | 1 |
| Crosara, S | 2 |
| Häggström, J | 1 |
| Lahmers, S | 1 |
| Rosenthal, S | 1 |
| Tyrrell, W | 1 |
| Ferasin, L | 1 |
| Lamb, K | 1 |
| Bussadori, C | 1 |
| Chiavegato, D | 1 |
| D'Agnolo, G | 1 |
| Migliorini, F | 1 |
| Poggi, M | 1 |
| Santilli, RA | 1 |
| Guillot, E | 1 |
| Garelli-Paar, C | 1 |
| Toschi Corneliani, R | 1 |
| Farina, F | 1 |
| Zani, A | 1 |
| Dirven, M | 1 |
| Smets, P | 1 |
| Guglielmini, C | 1 |
| Oliveira, P | 1 |
| Di Marcello, M | 1 |
| Porciello, F | 1 |
| Ciaramella, P | 1 |
| Piantedosi, D | 1 |
| Smith, S | 1 |
| Vannini, S | 1 |
| Dall'Aglio, E | 1 |
| Savarino, P | 1 |
| Quintavalla, C | 1 |
| Patteson, M | 1 |
| Silva, J | 1 |
| Locatelli, C | 2 |
| Baron Toaldo, M | 1 |
| Galizzi, A | 1 |
| Bagardi, M | 1 |
| Stranieri, A | 1 |
| Zanaboni, AM | 1 |
| Malchiodi, D | 1 |
| Borromeo, V | 1 |
| Brambilla, PG | 1 |
| Yan, S | 1 |
| Yu, J | 1 |
| Xia, Z | 1 |
| Zhu, B | 1 |
| Hu, J | 1 |
| Li, J | 1 |
| Hezzell, MJ | 1 |
| Boswood, A | 1 |
| López-Alvarez, J | 1 |
| Lötter, N | 1 |
| Elliott, J | 1 |
| Vinogradov, AV | 1 |
| Sycheva, IM | 1 |
| Zhuravleva, IA | 1 |
| Fleming, JS | 1 |
| Schröder, R | 1 |
| Ramdohr, B | 1 |
| Hüttemann, U | 1 |
| von Leitner, E | 1 |
| Schüren, KP | 1 |
| Beyer, J | 1 |
| Sebening, F | 1 |
| Valentin, N | 1 |
| Olesen, KH | 1 |
| Radó, JP | 1 |
| Marosi, J | 1 |
| Takó, J | 1 |
| Dévényi, I | 1 |
| Kaufmann, W | 2 |
| Steiner, B | 1 |
| Dürr, F | 2 |
| Meurer, KA | 1 |
| Behn, C | 1 |
| Neuhaus, GA | 1 |
| Praetorius, F | 1 |
| Horbach, L | 1 |
| Michaelis, J | 1 |
| Kühn, P | 1 |
| Probst, P | 1 |
| Gentili, G | 1 |
| Liberti, R | 1 |
| Judson, WE | 1 |
| Helmer, OM | 1 |
| Yasui, H | 1 |
| Awamura, M | 1 |
4 trials available for spironolactone and Heart Valve Diseases
| Article | Year |
|---|---|
DELay of Appearance of sYmptoms of Canine Degenerative Mitral Valve Disease Treated with Spironolactone and Benazepril: the DELAY Study.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Dog Diseases; Dogs; Echocardiograph | 2020 |
Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone-a pilot study.
Topics: Animals; Dog Diseases; Dogs; Female; Heart Valve Diseases; Male; Mitral Valve; Pilot Projects; Prosp | 2017 |
[Fluid redistribution between the extracellular medium and the cells in the diuretic therapy of cardiac insufficiency].
Topics: Adult; Aged; Body Water; Cardiac Glycosides; Clinical Trials as Topic; Coronary Disease; Diuretics; | 1975 |
[Direct positive inotropic influencing on the heart using oral spironolactone therapy].
Topics: Administration, Oral; Carbon Dioxide; Clinical Trials as Topic; Female; Heart Failure; Heart Valve D | 1972 |
14 other studies available for spironolactone and Heart Valve Diseases
| Article | Year |
|---|---|
The longitudinal outcome of canine (K9) myxomatous mitral valve disease (LOOK-Mitral) registry: Baseline treatment characteristics.
Topics: Animals; Cardiotonic Agents; Dog Diseases; Dogs; Heart Failure; Heart Valve Diseases; Mitral Valve; | 2022 |
Factors affecting the urinary aldosterone-to-creatinine ratio in healthy dogs and dogs with naturally occurring myxomatous mitral valve disease.
Topics: Aldosterone; Animals; Creatinine; Dog Diseases; Dogs; Female; Furosemide; Heart Valve Diseases; Male | 2021 |
A rare form of extremely wide QRS complex due to reversed homologous electrical ventricular separation of acute heart failure.
Topics: Acute Disease; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzaze | 2018 |
Heart failure and cardiac arrhythmias.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Diuretics; Electroconvulsive The | 1974 |
[Aldosterone-antagonists in heart surgery. Influence of the pre- and post-operative treatment using specific aldosterone-antagonists].
Topics: Administration, Oral; Diuresis; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Postoperative | 1973 |
Muscle electrolytes and total exchangeable electrolytes in patients with cardiac diseases.
Topics: Adult; Age Factors; Aortic Valve Stenosis; Body Water; Chlorides; Cytoplasm; Digoxin; Diuretics; Ext | 1973 |
Hyperkalemic intermittent paralysis associated with spironolactone in a patient with cardiac cirrhosis.
Topics: Acetazolamide; Adult; Aldosterone; Ascites; Female; Furosemide; Heart Failure; Heart Valve Diseases; | 1968 |
[Induced aldosteronism in hydropic heart insufficiency].
Topics: Acid-Base Equilibrium; Adult; Aged; Aldosterone; Body Weight; Carbon Isotopes; Cardiac Glycosides; E | 1969 |
[Effect of diuretic measures in hydropic conditions. I. Planning, results in heart insufficiency].
Topics: Adult; Aged; Body Weight; Diet, Sodium-Restricted; Diuresis; Diuretics; Documentation; Edema; Female | 1969 |
[Acid-base equilibrium and blood gas analysis in clinical cardiology].
Topics: Acetazolamide; Acid-Base Equilibrium; Bicarbonates; Blood Gas Analysis; Body Weight; Diagnosis, Diff | 1970 |
[Clinical study of the use of "Spirolang" 50].
Topics: Adult; Aged; Ascites; Chronic Disease; Digitalis Glycosides; Diuresis; Electrolytes; Ethacrynic Acid | 1971 |
Relationship of cardiorenal function to renin-aldosterone system in patients with valvular heart disease.
Topics: Aldosterone; Blood Pressure; Cardiac Volume; Diuretics; Heart; Heart Valve Diseases; Kidney; Natriur | 1971 |
The role of catecholamines in circulatory regulation on the chronic congestive heart failure. Clinical study of the urinary catecholamine excretion in the patients with chronic congestive heart failure.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiomyopathies; Catecholamines; Coronary Disease; Digital | 1968 |
Clinical studies on the acid-base balance disturbance in congestive heart failure.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Adult; Aldosterone; Alkalosis; Arteries; Benzothiadiaz | 1969 |