spironolactone has been researched along with HIV Coinfection in 7 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Blood samples were collected prior and after the directly observed dosing (0, 0." | 3.30 | Estradiol and Spironolactone Plasma Pharmacokinetics Among Brazilian Transgender Women Using HIV Pre-Exposure Prophylaxis: Analysis of Potential Interactions. ( Anderson, P; Bushman, L; Castro, CRV; Cattani, VB; Eksterman, L; Estrela, R; Grinsztejn, B; Jalil, EM; Monteiro, L; Torres, T; Veloso, VG; Wagner Cardoso, S; Wilson, E, 2023) |
| "No differences in tenofovir and emtricitabine plasma PK parameters were observed between the short-term PK of noFHT (n = 12) and sFHT participants (n = 18), except for emtricitabine Cmax [GMR: 1." | 1.72 | Impact of feminizing hormone therapy on tenofovir and emtricitabine plasma pharmacokinetics: a nested drug-drug interaction study in a cohort of Brazilian transgender women using HIV pre-exposure prophylaxis. ( Anderson, P; Bushman, L; Cardoso, SW; Castro, CRV; Cattani, VB; Eksterman, L; Estrela, R; Grinsztejn, B; Jalil, EM; Monteiro, L; Torres, T; Veloso, VG; Wilson, E, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Cattani, VB | 2 |
| Jalil, EM | 2 |
| Eksterman, L | 2 |
| Torres, T | 2 |
| Cardoso, SW | 1 |
| Castro, CRV | 2 |
| Monteiro, L | 2 |
| Wilson, E | 2 |
| Bushman, L | 2 |
| Anderson, P | 2 |
| Veloso, VG | 2 |
| Grinsztejn, B | 2 |
| Estrela, R | 2 |
| Srinivasa, S | 1 |
| Walpert, AR | 1 |
| Thomas, TS | 1 |
| Huck, DM | 1 |
| Jerosch-Herold, M | 1 |
| Islam, S | 1 |
| Lu, MT | 1 |
| Burdo, TH | 1 |
| deFilippi, CR | 1 |
| Dunderdale, CN | 1 |
| Feldpausch, M | 1 |
| Iyengar, S | 1 |
| Shen, G | 1 |
| Baak, S | 1 |
| Torriani, M | 1 |
| Robbins, GK | 1 |
| Lee, H | 1 |
| Kwong, R | 1 |
| DiCarli, M | 1 |
| Adler, GK | 1 |
| Grinspoon, SK | 1 |
| Wagner Cardoso, S | 1 |
| Johnson, EL | 1 |
| Kaplan, PW | 1 |
| Lacombe, B | 1 |
| Morel, M | 1 |
| Margottin-Goguet, F | 1 |
| Ramirez, BC | 1 |
| Sanchez, NF | 1 |
| Sanchez, JP | 1 |
| Danoff, A | 1 |
| Stricker, RB | 1 |
| Goldberg, DA | 1 |
| Hu, C | 1 |
| Hsu, JW | 1 |
| Goldberg, B | 1 |
1 review available for spironolactone and HIV Coinfection
| Article | Year |
|---|---|
Caring for transgender patients with epilepsy.
Topics: Androgens; Anti-HIV Agents; Anticonvulsants; Antidepressive Agents; Anxiety Disorders; Comorbidity; | 2017 |
2 trials available for spironolactone and HIV Coinfection
| Article | Year |
|---|---|
Randomized Placebo-Controlled Trial to Evaluate Effects of Eplerenone on Myocardial Perfusion and Function Among Persons With Human Immunodeficiency Virus (HIV)-Results From the MIRACLE HIV Study.
Topics: Eplerenone; HIV; HIV Infections; Humans; Mineralocorticoid Receptor Antagonists; Perfusion; Spironol | 2023 |
Estradiol and Spironolactone Plasma Pharmacokinetics Among Brazilian Transgender Women Using HIV Pre-Exposure Prophylaxis: Analysis of Potential Interactions.
Topics: Adult; Anti-HIV Agents; Brazil; Canrenone; Estradiol; Female; HIV Infections; Humans; Male; Spironol | 2023 |
4 other studies available for spironolactone and HIV Coinfection
| Article | Year |
|---|---|
Impact of feminizing hormone therapy on tenofovir and emtricitabine plasma pharmacokinetics: a nested drug-drug interaction study in a cohort of Brazilian transgender women using HIV pre-exposure prophylaxis.
Topics: Anti-HIV Agents; Brazil; Cohort Studies; Drug Interactions; Emtricitabine; Estradiol; Female; HIV In | 2022 |
Specific Inhibition of HIV Infection by the Action of Spironolactone in T Cells.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Helicases; DNA-Binding Proteins; H | 2016 |
Health care utilization, barriers to care, and hormone usage among male-to-female transgender persons in New York City.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Community Health Services; Estrogens; Female; Health | 2009 |
A syndrome resembling primary aldosteronism (Conn syndrome) in untreated HIV disease.
Topics: HIV Infections; Humans; Hyperaldosteronism; Male; Middle Aged; Mineralocorticoid Receptor Antagonist | 1999 |