spironolactone has been researched along with Gout in 9 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with spironolactone did not affect the biomarker of fibrosis Gal-3 in AF patients." | 5.41 | Galectin-3 in patients with atrial fibrillation and restored sinus rhythm. ( Angelov, A; Bocheva, Y; Chervenkov, T; Kisheva, A; Yotov, Y, 2021) |
| "Dark red nodules that drained an opaque amber liquid developed on the extensor surfaces of both legs in a 69-year-old woman receiving furosemide and spironolactone for congestive heart failure." | 3.65 | Panniculitis of the legs with urate crystal deposition. ( Niemi, KM, 1977) |
| "Hypertension is the leading cause of early mortality in the world, and reduction of blood pressure can help to reduce that burden." | 2.53 | Update in Hypertension Therapy. ( Mankin, LA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kisheva, A | 1 |
| Yotov, Y | 1 |
| Chervenkov, T | 1 |
| Angelov, A | 1 |
| Bocheva, Y | 1 |
| Mankin, LA | 1 |
| SIMPSON, FO | 1 |
| WAAL, HJ | 1 |
| Bufalari, A | 1 |
| Meloni, G | 1 |
| Niemi, KM | 1 |
| Zweifler, AJ | 1 |
| Esler, M | 1 |
| Mertz, DP | 1 |
| Ravera, M | 1 |
| Spaziante, B | 1 |
| Rastogi, SP | 1 |
| Volans, G | 1 |
| Elliott, RW | 1 |
| Eccleston, DW | 1 |
| Ashcroft, R | 1 |
| Webster, D | 1 |
| Kerr, DN | 1 |
1 review available for spironolactone and Gout
| Article | Year |
|---|---|
Update in Hypertension Therapy.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2016 |
1 trial available for spironolactone and Gout
| Article | Year |
|---|---|
Galectin-3 in patients with atrial fibrillation and restored sinus rhythm.
Topics: Aged; Atrial Fibrillation; Biomarkers; Female; Fibrosis; Galectin 3; Gout; Humans; Kidney Diseases; | 2021 |
7 other studies available for spironolactone and Gout
| Article | Year |
|---|---|
CLINICAL TRIAL OF TRIAMTERENE IN HYPERTENSIVE PATIENTS.
Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure Determination; Diuretics; Gout; Hyperal | 1964 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Panniculitis of the legs with urate crystal deposition.
Topics: Aged; Arthritis; Diagnosis, Differential; Female; Furosemide; Gout; Heart Failure; Humans; Lipase; S | 1977 |
Factors influencing the choice of antihypertensive agents.
Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications; | 1976 |
[The effect of spironolactone and thiabutazide on serum-uric acid and lipid levels in patients with gout and in healthy persons].
Topics: Adult; Allopurinol; Benzothiadiazines; Cholesterol; Female; Follow-Up Studies; Gout; Humans; Lipids; | 1973 |
[Hyperuricemia due to diuretics].
Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; H | 1973 |
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure.
Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, R | 1971 |