spironolactone has been researched along with Glomerulonephritis, Minimal Change in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 32-year-old female with a relapsing minimal-change nephrotic syndrome developed a massive pulmonary embolism during the treatment of prednisolone and diuretics." | 3.66 | Massive pulmonary embolism occurring with corticosteroid and diuretics therapy in a minimal-change nephrotic patient. ( Fujimi, S; Maeda, T; Ohryoji, F; Omae, T; Onoyama, K; Shimamatsu, K, 1982) |
| "Proteinuria was decreased in groups MR and AR compared with group P (on day 14 after PAN administration, respectively; group P vs AR, P < 0." | 1.36 | Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome. ( Fujimoto, S; Fukuda, A; Iwatsubo, S; Kawachi, H; Kitamura, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuda, A | 1 |
| Fujimoto, S | 1 |
| Iwatsubo, S | 1 |
| Kawachi, H | 1 |
| Kitamura, K | 1 |
| JEUNE, M | 1 |
| SALLE, B | 1 |
| PUGEAUT, R | 1 |
| BONNEFOY, S | 1 |
| POLIANTSEVA, LR | 1 |
| ERMOLENKO, VM | 1 |
| ANAGNOSTOPOULOS, T | 1 |
| Shimamatsu, K | 1 |
| Onoyama, K | 1 |
| Maeda, T | 1 |
| Ohryoji, F | 1 |
| Fujimi, S | 1 |
| Omae, T | 1 |
| Fornara, P | 1 |
6 other studies available for spironolactone and Glomerulonephritis, Minimal Change
| Article | Year |
|---|---|
Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Eplerenone | 2010 |
[Apropos of a pure lipoid nephrosis in a child treated with spirolactone].
Topics: Aldosterone; Child; Diuretics; Infant; Mineralocorticoid Receptor Antagonists; Nephrosis, Lipoid; Ne | 1961 |
[ALDOSTERONE AND SPIROLACTONES IN THE CLINICAL TREATMENT OF INTERNAL DISEASES (REVIEW OF THE LITERATURE AND ANALYSIS OF PERSONAL CASES)].
Topics: Albuminuria; Aldosterone; Blood; Cardiovascular Diseases; Drug Therapy; Humans; Hyperaldosteronism; | 1963 |
[TREATMENT OF THE IDIOPATHIC NEPHROTIC SYNDROME IN CHILDREN].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Child; Chlorothiazide; | 1964 |
Massive pulmonary embolism occurring with corticosteroid and diuretics therapy in a minimal-change nephrotic patient.
Topics: Adult; Disseminated Intravascular Coagulation; Dose-Response Relationship, Drug; Female; Furosemide; | 1982 |
[Considerations on therapy of genuine nephrotic syndrome in childhood].
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Diet Therapy; Dietary Proteins; Diuretics; Humans; | 1968 |