spironolactone has been researched along with Glioma in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakatani, Y | 1 |
| Amano, T | 1 |
| Takeda, H | 1 |
| Pandia, MP | 1 |
| Bithal, PK | 1 |
| Gupta, M | 1 |
| Beaumont, K | 1 |
3 other studies available for spironolactone and Glioma
| Article | Year |
|---|---|
Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Corticosterone; Glioma; Hormone Antago | 2016 |
Life-threatening hyperkalemia in the intraoperative period.
Topics: Brain Neoplasms; Decompression, Surgical; Diabetes Complications; Diuretics; Glioma; Humans; Hyperka | 2004 |
Rat C6 glioma cells contain type I as well as type II corticosteroid receptors.
Topics: Adrenal Cortex Hormones; Aldosterone; Androstanols; Animals; Cell Line; Corticosterone; Desoxycortic | 1985 |