spironolactone has been researched along with Feminization in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Feminization: Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liszewski, W | 1 |
| Boull, C | 1 |
| Adams, C | 1 |
| Kumar, R | 1 |
| Hecker, A | 1 |
| Hasan, SH | 1 |
| Neumann, F | 1 |
1 review available for spironolactone and Feminization
| Article | Year |
|---|---|
Lack of evidence for feminization of males exposed to spironolactone in utero: A systematic review.
Topics: Animals; Diuretics; Edema; Female; Feminization; Humans; Male; Pregnancy; Pregnancy Complications; P | 2019 |
2 other studies available for spironolactone and Feminization
| Article | Year |
|---|---|
The effect of estrogen in a man with Parkinson's disease and a review of its therapeutic potential.
Topics: Antiparkinson Agents; Drug Implants; Estrogens; Feminization; Gender Identity; Humans; Levodopa; Mal | 2013 |
Disturbances in sexual differentiation of rat foetuses following spironolactone treatment.
Topics: Animals; Female; Feminization; Fetus; Male; Penis; Pregnancy; Prostate; Rats; Sex Differentiation; S | 1980 |