spironolactone has been researched along with Failure to Thrive in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Failure to Thrive: A condition of substandard growth or diminished capacity to maintain normal function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The lack of therapeutic response to spironolactone, with a good response to amiloride and recurrence of hypertension and metabolic alkalosis after amiloride cessation that was subsequently treated with amiloride, established the diagnosis of Liddle syndrome." | 3.71 | Liddle syndrome in a newborn infant. ( Assadi, FK; Kimura, RE; Patel, S; Subramanian, U, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Skalova, S | 1 |
| Neuman, D | 1 |
| Lnenicka, P | 1 |
| Stekrova, J | 1 |
| Assadi, FK | 1 |
| Kimura, RE | 1 |
| Subramanian, U | 1 |
| Patel, S | 1 |
| Müller-Berghaus, J | 1 |
| Homoki, J | 1 |
| Michalk, DV | 1 |
| Querfeld, U | 1 |
3 other studies available for spironolactone and Failure to Thrive
| Article | Year |
|---|---|
Gitelman syndrome as a cause of psychomotor retardation in a toddler.
Topics: Dietary Supplements; Diuretics; Failure to Thrive; Gitelman Syndrome; Humans; Infant; Male; Potassiu | 2013 |
Liddle syndrome in a newborn infant.
Topics: Alkalosis; Amiloride; Blood Pressure; Diuretics; Electrolytes; Failure to Thrive; Female; Humans; Hy | 2002 |
Diagnosis and treatment of a child with the syndrome of apparent mineralocorticoid excess type 1.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Failure to Thrive; Female; Fetal Growth Retardation; Humans; | 1996 |