spironolactone has been researched along with Extrasystole, Ventricular in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We documented chronic ventricular arrhythmias in a first group of 58 rats after myocardial infarction (MI), then assessed the effects of spironolactone and fosinopril on morphological indexes and arrhythmias in a second group (n = 33)." | 7.71 | Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction. ( Beck, L; Blanc-Guillemaud, V; Cherif, OK; Davy, JM; Jover, B, 2001) |
| "Ventricular arrhythmia was recognized as the most common cause of death in this population." | 6.69 | Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. ( Coelho, O; Gruppi, CJ; Mady, C; Mansur, A; Maranhão, M; Ramires, FJ; Ramires, JA, 2000) |
| "We documented chronic ventricular arrhythmias in a first group of 58 rats after myocardial infarction (MI), then assessed the effects of spironolactone and fosinopril on morphological indexes and arrhythmias in a second group (n = 33)." | 3.71 | Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction. ( Beck, L; Blanc-Guillemaud, V; Cherif, OK; Davy, JM; Jover, B, 2001) |
| "Ivabradine is a safe and effective drug in reducing resting heart rate, improving NYHA functional class without undesirable effects on conduction parameters or ectopic activity." | 2.76 | Ivabradine, a novel heart rate slower: is it a sword of double blades in patients with idiopathic dilated cardiomyopathy? ( Alabd, A; Gamal, A; Rayan, M; Tawfik, M, 2011) |
| "Ventricular arrhythmia was recognized as the most common cause of death in this population." | 2.69 | Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy. ( Coelho, O; Gruppi, CJ; Mady, C; Mansur, A; Maranhão, M; Ramires, FJ; Ramires, JA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rayan, M | 1 |
| Tawfik, M | 1 |
| Alabd, A | 1 |
| Gamal, A | 1 |
| Ramires, FJ | 1 |
| Mansur, A | 1 |
| Coelho, O | 1 |
| Maranhão, M | 1 |
| Gruppi, CJ | 1 |
| Mady, C | 1 |
| Ramires, JA | 1 |
| Beck, L | 1 |
| Blanc-Guillemaud, V | 1 |
| Cherif, OK | 1 |
| Jover, B | 1 |
| Davy, JM | 1 |
2 trials available for spironolactone and Extrasystole, Ventricular
| Article | Year |
|---|---|
Ivabradine, a novel heart rate slower: is it a sword of double blades in patients with idiopathic dilated cardiomyopathy?
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzazepines; Carbazoles; C | 2011 |
Effect of spironolactone on ventricular arrhythmias in congestive heart failure secondary to idiopathic dilated or to ischemic cardiomyopathy.
Topics: Analysis of Variance; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Death, | 2000 |
1 other study available for spironolactone and Extrasystole, Ventricular
| Article | Year |
|---|---|
Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; Chronic Disease; Disease Mo | 2001 |