spironolactone has been researched along with Experimental Neoplasms in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Feldman, RD | 1 |
Ding, Q | 1 |
Hussain, Y | 1 |
Limbird, LE | 1 |
Pickering, JG | 1 |
Gros, R | 1 |
Somogyi, A | 1 |
Kovacs, K | 1 |
Clarkson, EM | 1 |
Luck, VA | 1 |
1 review available for spironolactone and Experimental Neoplasms
Article | Year |
---|---|
Spironolactone.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Humans; Male; Mice; Neoplasms, Experimental; Rabbits | 1980 |
3 other studies available for spironolactone and Experimental Neoplasms
Article | Year |
---|---|
Aldosterone mediates metastatic spread of renal cancer via the G protein-coupled estrogen receptor (GPER).
Topics: Aldosterone; Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Kid | 2016 |
Effect of stress on the adrenocorticolytic and carcinogenic action of 7,12-dimethylbenz(a)anthracene.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Necrosis; Neoplasms, Experimental; Physical Exertion; R | 1971 |
The effect of spironolactone on sodium transport in the absence of aldosterone.
Topics: Aldosterone; Animals; Ascites; Biological Transport; Carcinoma; Depression, Chemical; Erythrocytes; | 1970 |