Page last updated: 2024-11-07

spironolactone and Experimental Neoplasms

spironolactone has been researched along with Experimental Neoplasms in 4 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feldman, RD1
Ding, Q1
Hussain, Y1
Limbird, LE1
Pickering, JG1
Gros, R1
Somogyi, A1
Kovacs, K1
Clarkson, EM1
Luck, VA1

Reviews

1 review available for spironolactone and Experimental Neoplasms

ArticleYear
Spironolactone.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1980, Volume: 24

    Topics: Animals; Chemical Phenomena; Chemistry; Female; Humans; Male; Mice; Neoplasms, Experimental; Rabbits

1980

Other Studies

3 other studies available for spironolactone and Experimental Neoplasms

ArticleYear
Aldosterone mediates metastatic spread of renal cancer via the G protein-coupled estrogen receptor (GPER).
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:6

    Topics: Aldosterone; Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Kid

2016
Effect of stress on the adrenocorticolytic and carcinogenic action of 7,12-dimethylbenz(a)anthracene.
    Zeitschrift fur Krebsforschung, 1971, Volume: 75, Issue:4

    Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Necrosis; Neoplasms, Experimental; Physical Exertion; R

1971
The effect of spironolactone on sodium transport in the absence of aldosterone.
    Clinical science, 1970, Volume: 39, Issue:6

    Topics: Aldosterone; Animals; Ascites; Biological Transport; Carcinoma; Depression, Chemical; Erythrocytes;

1970