spironolactone has been researched along with End Stage Liver Disease in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
End Stage Liver Disease: Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients without hyperkalemia were administrated 100 mg of spironolactone/day." | 9.22 | High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis. ( Demir, M; Dogan, O; Ozer, B; Parlakgumus, A; Serin, E; Yakar, T, 2016) |
| " Patients without hyperkalemia were administrated 100 mg of spironolactone/day." | 5.22 | High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis. ( Demir, M; Dogan, O; Ozer, B; Parlakgumus, A; Serin, E; Yakar, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perri, GA | 1 |
| Yakar, T | 1 |
| Demir, M | 1 |
| Dogan, O | 1 |
| Parlakgumus, A | 1 |
| Ozer, B | 1 |
| Serin, E | 1 |
1 trial available for spironolactone and End Stage Liver Disease
| Article | Year |
|---|---|
High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Albumins; Ascites; Bilirubin; Creatinine; End | 2016 |
1 other study available for spironolactone and End Stage Liver Disease
| Article | Year |
|---|---|
Ascites in patients with cirrhosis.
Topics: Abdominal Pain; Aged; Analgesics, Opioid; Ascites; Catheters, Indwelling; Diet, Sodium-Restricted; D | 2013 |