spironolactone has been researched along with Encapsulating Peritoneal Sclerosis in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peritoneal fibrosis is a complication of patients with long-term continuous ambulatory peritoneal dialysis (CAPD)." | 1.40 | The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis. ( Ding, JL; Hao, JB; Hao, LR; Ren, LS; Zhang, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vazquez-Rangel, A | 1 |
| Soto, V | 1 |
| Escalona, M | 1 |
| Toledo, RG | 1 |
| Castillo, EA | 1 |
| Polanco Flores, NA | 1 |
| Falcon-Chavez, I | 1 |
| Madero, M | 1 |
| Zhang, L | 1 |
| Hao, JB | 1 |
| Ren, LS | 1 |
| Ding, JL | 1 |
| Hao, LR | 1 |
1 trial available for spironolactone and Encapsulating Peritoneal Sclerosis
| Article | Year |
|---|---|
Spironolactone to prevent peritoneal fibrosis in peritoneal dialysis patients: a randomized controlled trial.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Mineralocorticoid Receptor Anta | 2014 |
1 other study available for spironolactone and Encapsulating Peritoneal Sclerosis
| Article | Year |
|---|---|
The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Cilazapril | 2014 |