spironolactone has been researched along with Ectopic ACTH Syndrome in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The addition of spironolactone to her previous medications controlled and normalized hypertension, hypokalemia, and hormonal abnormalities within 4 months." | 7.76 | Resistant hypertension in an aged woman presenting with clinical features simulating ectopic ACTH syndrome--response to spironolactone--. ( Harada, E; Mizuno, Y; Morikawa, Y; Nakagawa, H; Saito, Y; Semba, F; Yasue, H; Yoshimura, M, 2010) |
| " The addition of spironolactone to her previous medications controlled and normalized hypertension, hypokalemia, and hormonal abnormalities within 4 months." | 3.76 | Resistant hypertension in an aged woman presenting with clinical features simulating ectopic ACTH syndrome--response to spironolactone--. ( Harada, E; Mizuno, Y; Morikawa, Y; Nakagawa, H; Saito, Y; Semba, F; Yasue, H; Yoshimura, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simó-Servat, A | 1 |
| Peiró, I | 1 |
| Villabona, C | 1 |
| Harada, E | 1 |
| Yasue, H | 1 |
| Mizuno, Y | 1 |
| Morikawa, Y | 1 |
| Nakagawa, H | 1 |
| Semba, F | 1 |
| Yoshimura, M | 1 |
| Saito, Y | 1 |
| Aron, DC | 1 |
| Tyrrell, JB | 1 |
| Fitzgerald, PA | 1 |
| Findling, JW | 1 |
| Forsham, PH | 1 |
3 other studies available for spironolactone and Ectopic ACTH Syndrome
| Article | Year |
|---|---|
Corticotropin secreting pancreatic neuroendocrine tumour, a therapeutic management challenge. A presentation of 2 cases.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Chromogranins; Combined Modality Therapy; Embol | 2019 |
Resistant hypertension in an aged woman presenting with clinical features simulating ectopic ACTH syndrome--response to spironolactone--.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Ag | 2010 |
Cushing's syndrome: problems in diagnosis.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adrenal Cortex Function Tests; Adrenocortical Hyperfunction; Adult; | 1981 |