spironolactone has been researched along with Diabetic Retinopathy in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of severe diabetic macular edema (DME) that developed after pioglitazone was used by a patient with proliferative diabetic retinopathy." | 7.74 | Severe macular edema induced by pioglitazone in a patient with diabetic retinopathy: a case study. ( Asaumi, N; Kumagai, K; Mitamura, Y; Oshitari, T; Watanabe, M, 2008) |
| "We report a case of severe diabetic macular edema (DME) that developed after pioglitazone was used by a patient with proliferative diabetic retinopathy." | 3.74 | Severe macular edema induced by pioglitazone in a patient with diabetic retinopathy: a case study. ( Asaumi, N; Kumagai, K; Mitamura, Y; Oshitari, T; Watanabe, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, M | 1 |
| Gelize, E | 1 |
| Levy, R | 1 |
| Moulin, A | 1 |
| Azan, F | 1 |
| Berdugo, M | 1 |
| Naud, MC | 1 |
| Guegan, J | 1 |
| Delaunay, K | 1 |
| Pussard, E | 1 |
| Lassiaz, P | 1 |
| Bravo-Osuna, I | 1 |
| Herrero-Vanrell, R | 1 |
| Behar-Cohen, F | 1 |
| Oshitari, T | 1 |
| Asaumi, N | 1 |
| Watanabe, M | 1 |
| Kumagai, K | 1 |
| Mitamura, Y | 1 |
2 other studies available for spironolactone and Diabetic Retinopathy
| Article | Year |
|---|---|
Mineralocorticoid Receptor Pathway and Its Antagonism in a Model of Diabetic Retinopathy.
Topics: Animals; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Gene | 2021 |
Severe macular edema induced by pioglitazone in a patient with diabetic retinopathy: a case study.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diuretics; Female; Fluorescein Angiography; | 2008 |