Page last updated: 2024-11-07

spironolactone and Cough

spironolactone has been researched along with Cough in 1 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"This study compared the efficacy and tolerability of eplerenone and enalapril in 499 patients with stage 1 or 2 hypertension who were randomized to receive eplerenone or enalapril for 6 months in a 3-step titration-to-effect study."9.11Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension. ( Burgess, E; Kipnes, MS; Kolloch, RE; Krause, SL; Niegowska, J; Patrick, JL; Roniker, B; Ruilope, LM; Williams, GH, 2004)
"This study compared the efficacy and tolerability of eplerenone and enalapril in 499 patients with stage 1 or 2 hypertension who were randomized to receive eplerenone or enalapril for 6 months in a 3-step titration-to-effect study."5.11Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension. ( Burgess, E; Kipnes, MS; Kolloch, RE; Krause, SL; Niegowska, J; Patrick, JL; Roniker, B; Ruilope, LM; Williams, GH, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williams, GH1
Burgess, E1
Kolloch, RE1
Ruilope, LM1
Niegowska, J1
Kipnes, MS1
Roniker, B1
Patrick, JL1
Krause, SL1

Trials

1 trial available for spironolactone and Cough

ArticleYear
Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension.
    The American journal of cardiology, 2004, Apr-15, Volume: 93, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Antihypertensive Agents; Blood Pressure; Cough; Drug To

2004