spironolactone has been researched along with Constriction, Pathological in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spironolactone was less effective, and aldosterone tended to exert opposite effects on coronary artery structure after angioplasty." | 1.31 | Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. ( Bobik, A; Funder, J; Kanellakis, P; Ramsey, D; Ward, MR, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mittal, SR | 1 |
| Kuster, GM | 1 |
| Kotlyar, E | 1 |
| Rude, MK | 1 |
| Siwik, DA | 1 |
| Liao, R | 1 |
| Colucci, WS | 1 |
| Sam, F | 1 |
| Ward, MR | 1 |
| Kanellakis, P | 1 |
| Ramsey, D | 1 |
| Funder, J | 1 |
| Bobik, A | 1 |
3 other studies available for spironolactone and Constriction, Pathological
| Article | Year |
|---|---|
Transient pericardial constriction.
Topics: Adult; Antitubercular Agents; Constriction, Pathologic; Diuretics; Echocardiography; Female; Furosem | 2013 |
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload.
Topics: Animals; Aorta; Apoptosis; Blood Pressure; Cell Size; Chronic Disease; Constriction, Pathologic; Dru | 2005 |
Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries.
Topics: Aldosterone; Angioplasty, Balloon; Animals; Collagen; Constriction, Pathologic; Coronary Disease; Co | 2001 |