spironolactone has been researched along with Colorectal Neoplasms in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leung, WH | 1 |
| Vong, QP | 1 |
| Lin, W | 1 |
| Janke, L | 1 |
| Chen, T | 1 |
| Leung, W | 1 |
1 other study available for spironolactone and Colorectal Neoplasms
| Article | Year |
|---|---|
Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Cytotoxicity, Immunologic; GPI-Linked Proteins; His | 2013 |