spironolactone has been researched along with Cancer of Stomach in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bisphosphonate, tetracycline and spironolactone use has been shown to increase gastro-oesophageal inflammation, an accepted risk factor for cancer." | 3.85 | The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data. ( Busby, J; Cardwell, CR; Iversen, L; Lee, AJ; Murchie, P; Murray, L; Spence, A; Watson, MC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Busby, J | 1 |
| Murchie, P | 1 |
| Murray, L | 1 |
| Iversen, L | 1 |
| Lee, AJ | 1 |
| Spence, A | 1 |
| Watson, MC | 1 |
| Cardwell, CR | 1 |
| Davies, PG | 1 |
| Moertel, CG | 1 |
| Engstrom, P | 1 |
| Lavin, PT | 1 |
| Gelber, RD | 1 |
| Carbone, PP | 1 |
1 trial available for spironolactone and Cancer of Stomach
| Article | Year |
|---|---|
Chemotherapy of gastric and pancreatic carcinoma: a controlled evaluation of combinations of 5-fluorouracil with nitrosoureas and "lactones".
Topics: Adenocarcinoma; Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Lomustine; N | 1979 |
2 other studies available for spironolactone and Cancer of Stomach
| Article | Year |
|---|---|
The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data.
Topics: Adult; Aged; Aged, 80 and over; Diphosphonates; Esophageal Neoplasms; Female; Humans; Inflammation; | 2017 |
Spontaneous resolution of adenocarcinoma.
Topics: Adenocarcinoma; Aged; Female; Humans; Metoclopramide; Spironolactone; Stomach Neoplasms | 1984 |