spironolactone has been researched along with Bulimia Nervosa in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Bulimia Nervosa: An eating disorder that is characterized by a cycle of binge eating (BULIMIA or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced VOMITING, use of LAXATIVES or DIURETICS, excessive exercise, and FASTING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some case reports mention that Spironolactone, a mineral corticoid antagonist and aldosterone antagonist, reduces binging in patients with bulimia nervosa." | 9.13 | [No effect of spironolactone on bulimia nervosa symptoms]. ( Bühler, G; Chrenko, K; Danner, B; Müller-Bock, V; Rauh, S; von Wietersheim, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| von Wietersheim, J | 2 |
| Müller-Bock, V | 1 |
| Rauh, S | 2 |
| Danner, B | 2 |
| Chrenko, K | 2 |
| Bühler, G | 2 |
| Müler-Bock, V | 1 |
1 trial available for spironolactone and Bulimia Nervosa
| Article | Year |
|---|---|
[No effect of spironolactone on bulimia nervosa symptoms].
Topics: Adult; Bulimia Nervosa; Double-Blind Method; Female; Humans; Mineralocorticoid Receptor Antagonists; | 2008 |
1 other study available for spironolactone and Bulimia Nervosa
| Article | Year |
|---|---|
No effect of spironolactone on bulimia nervosa symptoms.
Topics: Adult; Bulimia Nervosa; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; | 2008 |