spironolactone has been researched along with Breast Diseases in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Breast Diseases: Pathological processes of the BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of spironolactone in resistant hypertension management is unclear." | 9.14 | Efficacy of spironolactone therapy in patients with true resistant hypertension. ( de Souza, F; Fiszman, R; Muxfeldt, E; Salles, G, 2010) |
| "The role of spironolactone in resistant hypertension management is unclear." | 5.14 | Efficacy of spironolactone therapy in patients with true resistant hypertension. ( de Souza, F; Fiszman, R; Muxfeldt, E; Salles, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Souza, F | 1 |
| Muxfeldt, E | 1 |
| Fiszman, R | 1 |
| Salles, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| HYpertension Therapy With Valsartan Versus EpleRenone for Obese Patients: A Randomized Clinical Trial[NCT03476616] | Phase 4 | 330 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for spironolactone and Breast Diseases
| Article | Year |
|---|---|
Efficacy of spironolactone therapy in patients with true resistant hypertension.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Breast Diseases; Diuretics; Follow-Up Studies | 2010 |